コア結合因子α3サブユニット

WordNet

remove the core or center from; "core an apple"
(computer science) a tiny ferrite toroid formerly used in a random access memory to store one bit of data; now superseded by semiconductor memories; "each core has three wires passing through it, providing the means to select and detect the contents of each bit" (同)magnetic core
a bar of magnetic material (as soft iron) that passes through a coil and serves to increase the inductance of the coil
the chamber of a nuclear reactor containing the fissile material where the reaction takes place
a small group of indispensable persons or things; "five periodicals make up the core of their publishing program" (同)nucleus, core group
a cylindrical sample of soil or rock obtained with a hollow drill
the center of an object; "the ball has a titanium core"
the central part of the Earth
be a contributing factor; "make things factor into a companys profitability"
any of the numbers (or symbols) that form a product when multiplied together
an independent variable in statistics
anything that contributes causally to a result; "a number of factors determined the outcome"
consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
executed with proper legal authority; "a binding contract"
the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
strip sewn over or along an edge for reinforcement or decoration
the capacity to attract and hold something
an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
a concept whose truth can be proved; "scientific hypotheses are not facts"
a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
first in order of importance; "the alpha male in the group of chimpanzees"; "the alpha star in a constellation is the brightest or main star"
the 1st letter of the Greek alphabet
the beginning of a series or sequence; "the Alpha and Omega, the first and the last, the beginning and the end"--Revelations
early testing stage of a software or hardware product; "alpha version"

PrepTutorEJDIC

〈C〉(果物の)『しん』 / 〈U〉(物事の)核心 / 〈C〉(電気の)磁心,磁極鉄心 / …‘の'しんを抜く
(…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
アルファ(ギリシア語アルファベットの第1字A,α;英語のA,aに相当) / アルファ星(星座の主星)

UpToDate Contents

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1. 急性骨髄性白血病の分子遺伝学 molecular genetics of acute myeloid leukemia
2. 急性骨髄性白血病における細胞遺伝学 cytogenetics in acute myeloid leukemia
3. 骨髄造血の制御 regulation of myelopoiesis
4. 骨格の正常な発達および骨形成ならびに骨吸収の調節 normal skeletal development and regulation of bone formation and resorption
5. 急性リンパ芽球性白血病における細胞遺伝学および分子遺伝学 cytogenetics and molecular genetics in acute lymphoblastic leukemia

English Journal

RUNX3 facilitates growth of Ewing sarcoma cells.

Bledsoe KL1, McGee-Lawrence ME, Camilleri ET, Wang X, Riester SM, van Wijnen AJ, Oliveira AM, Westendorf JJ.
Journal of cellular physiology.J Cell Physiol.2014 Dec;229(12):2049-56. doi: 10.1002/jcp.24663.
Ewing sarcoma is an aggressive pediatric small round cell tumor that predominantly occurs in bone. Approximately 85% of Ewing sarcomas harbor the EWS/FLI fusion protein, which arises from a chromosomal translocation, t(11:22)(q24:q12). EWS/FLI interacts with numerous lineage-essential transcription
PMID 24812032

Transcription factor T-bet regulates intraepithelial lymphocyte functional maturation.

Reis BS1, Hoytema van Konijnenburg DP1, Grivennikov SI2, Mucida D3.
Immunity.Immunity.2014 Aug 21;41(2):244-56. doi: 10.1016/j.immuni.2014.06.017.
The intestinal epithelium harbors large populations of activated and memory lymphocytes, yet these cells do not cause tissue damage in the steady state. We investigated how intestinal T cell effector differentiation is regulated upon migration to the intestinal epithelium. Using gene loss- and gain-
PMID 25148025

T-bet orchestrates CD8αα IEL differentiation.

Kwong B1, Lazarevic V2.
Immunity.Immunity.2014 Aug 21;41(2):169-71. doi: 10.1016/j.immuni.2014.08.003.
Very little is known about the transcription factor network that regulates the development of intestinal intraepithelial lymphocytes (IELs). In this issue of Immunity, Klose et al. (2014b) and Reis et al. (2014) demonstrate an essential role for T-bet in regulating the CD8αα IEL differentiation
PMID 25148017

Japanese Journal

Intrinsic transcriptional activation-inhibition domains of the polyomavirus enhancer binding protein 2/core binding factor alpha subunit revealed in the presence of the beta subunit.