WordNet
- permission to proceed; "the plane was given clearance to land"
- the distance by which one thing clears another; the space between them
- the bodily process of discharging waste matter (同)evacuation, excretion, excreting, voiding
- the murder of a competitor (同)liquidation
- the act of removing or getting rid of something (同)riddance
- the act of removing an unknown mathematical quantity by combining equations
- analysis of a problem into alternative possibilities followed by the systematic rejection of unacceptable alternatives (同)reasoning by elimination
- lack or fail to include; "The cost for the trip excludes food and beverages"
- prevent from being included or considered or accepted; "The bad results were excluded from the report"; "Leave off the top piece" (同)except, leave out, leave_off, omit, take_out
- prevent from entering; shut out; "The trees were shutting out all sunlight"; "This policy excludes people who have a criminal record from entering the country" (同)keep_out, shut out, shut
- remove from a contest or race; "The cyclist has eliminated all the competitors in the race"
- kill in large numbers; "the plague wiped out an entire population" (同)annihilate, extinguish, eradicate, wipe_out, decimate, carry off
- remove (an unknown variable) from two or more equations
- move people from their homes or country
- excrete or discharge from the body (同)void, empty
- create a vacuum in (a bulb, flask, reaction vessel)
- empty completely; "evacuate the bottle"
- move out of an unsafe location into safety; "After the earthquake, residents were evacuated"
PrepTutorEJDIC
- 〈U〉〈C〉(…の)取り片付け,除去,掃除《+『of』+『名』》 / 〈U〉〈C〉(積荷の)通関手続き,(船の)出港免状 / (またclearance sale)〈C〉大棚ざらいの売出し / 〈U〉〈C〉(手形の)決済,(小切手の)現金化 / 〈U〉〈C〉(二つの物の間の)あき,余裕;(特に)道路面・川の面から橋げたまでの高さ / 〈U〉〈C〉秘密情報の使用許可;(秘密情報を扱う人の)信頼性調査;公安調査
- (…の)除去,削除《+『of』+『名』》 / (競技の)予選
- (…から)…‘を'『除外する』,除く《+『名』+『from』+『名』》 / 〈見込み・可能性・疑いの余地など〉‘を'全く許さない
- (…から)…‘を'『取り除く』,削除する(get rid of)《+『名』+『from』+『名』》 / …‘を'考慮に入れない,無視する(disregard)
- …‘を'明け渡す,‘から'撤退する / (危険な所から安全な所へ)…‘を'移動させる,疎開させる《+『名』+『from』+『名』+『to』+『名』》 / 《文》…‘を'からにする / 《文》(…から)〈排出物〉‘を'出す,排出する,《+『名』+『from』+『名』》
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/11/06 01:13:28」(JST)
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- 1. クレアチニンクリアランスの計算 calculation of the creatinine clearance
- 2. 腎機能の評価 assessment of kidney function
- 3. Dosing of anticancer agents in adults
- 4. 持続的腹膜透析における溶質クリアランスの測定：Kt/Vとクレアチニンクリアランス measurement of solute clearance in continuous peritoneal dialysis kt v and creatinine clearance
- 5. Nummular eczema
English Journal
- Altered regulation of renal nitric oxide and atrial natriuretic peptide systems in angiotensin II-induced hypertension.
- Bae EH, Ma SK, Lee J, Kim SW.SourceDepartment of Internal Medicine, Chonnam National University Medical School, Gwangju, Republic of Korea.
- Regulatory peptides.Regul Pept.2011 Oct 10;170(1-3):31-7. Epub 2011 May 25.
- The present study was aimed to determine whether there is an altered role of local nitric oxide (NO) and atrial natriuretic peptide (ANP) systems in the kidney in association with the angiotensin (Ang) II-induced hypertension. Male Sprague-Dawley rats were used. Ang II (100ng・min(-1)・kg(-1)) was i
- PMID 21616096
- ATRA-induced upregulation of Beclin 1 prolongs the life span of differentiated acute promyelocytic leukemia cells.
- Trocoli A, Mathieu J, Priault M, Reiffers J, Souquere S, Pierron G, Besancon F, Djavaheri-Mergny M.SourceINSERM U916 VINCO; Institut Bergonie; Bordeaux, France; Universite Victor Segalen Bordeaux; Bordeaux, France.
- Autophagy.Autophagy.2011 Oct 1;7(10). [Epub ahead of print]
- Acute promyelocytic leukemia (APL) results from a blockade of granulocyte differentiation at the promyelocytic stage. All-trans retinoic acid (ATRA) has been shown to induce clinical remission in APL patients by enhancing the rapid differentiation of APL cells and the clearance of PML-RAR alpha, APL
- PMID 21691148
- Evaluating the effect of vehicle modification in reducing injuries from landmine blasts. An analysis of 2212 incidents and its application for humanitarian purposes.
- Ramasamy A, Hill AM, Masouros SD, Gordon F, Clasper JC, Bull AM.SourceImperial Blast Biomechanics and Biophysics Group Dept of Bioengineering, Rm. 4.28, Royal School of Mines, Imperial College London, London SW7 2AZ, UK.
- Accident; analysis and prevention.Accid Anal Prev.2011 Sep;43(5):1878-86. Epub 2011 May 24.
- INTRODUCTION: Anti-vehicle (AV) mines have been laid indiscriminately in conflict areas for the past 100 years. With an indeterminate life-span they continue to pose a significant threat to the civilian population, as well as restrict the movement of people, aid and goods to vulnerable populations.
- PMID 21658517
Japanese Journal
- Characterization of plasma triiodophenol binding proteins in vertebrates and tissue distribution of triiodophenol in Rana catesbeiana tadpoles
- Yamauchi Kiyoshi,Sai Gobun
- Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology 153(3), 328-335, 2011-04
- … The differences in the molecular and binding properties of TIP binding proteins among vertebrates would affect in part the cellular availability, tissue distribution and clearance of TIP. …
- NAID 120002954721
- 取水槽内の空気吸込の発生について
- 平田 勝哉,舟木 治郎,久保田 義啓,稲垣 勝久,田岡 未樹
- 同志社大学理工学研究報告 52(1), 1-17, 2011-04
- … As the geometric parameters, we consider back clearance X, sump breadth B and bottom clearance Z. …
- NAID 110008441225
- In vivo relationship between thalamic nicotinic acetylcholine receptor occupancy rates and antiallodynic effects in a rat model of neuropathic pain: persistent agonist binding inhibits the expression of antiallodynic effects.
- Ueda Masashi,Iida Yasuhiko,Yoneyama Tomoki,Kawai Tomoki,Ogawa Mikako,Magata Yasuhiro,Saji Hideo
- Synapse 65(1), 77-83, 2011-01
- … These findings suggest that not clearance of 5IA but desensitization of nAChRs caused by persistent binding of 5IA is responsible for the disappearance of antiallodynic effects. …
- NAID 120002949727
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- 辞書 eプログレッシブ英和中辞典 (英和辞書) clearance [名] 1 (1)[U][C]取りかたづけ ，除去，撤去，排除 slum clearanceスラム街の一掃.(2)棚ざらえ，蔵払い，見切り売り ，在庫一掃セール(clearance sale) hold.
Related Pictures
★リンクテーブル★
| リンク元 | 「クリアランス」「elimination」「eliminate」「exclude」「evacuation」 |
「クリアランス」
定義
- 1. ある物質について、単位時間あたりどれだけの量の血液をきれいにできるか。
- 2. ある物質が排泄されるために必要な単位時間あたりの血漿量
- 3. ある物質が単位時間に腎によって完全に除去(清掃)される血漿の量 (生理学実習1 実習テキスト p.4,SP.777-778)
- 4. it is defined as the rate of elimination of the drug from the body relative to the concentration of the drug in plasma
(PPC.42) [(amount/time)/(amount/volume)]
- 5. clearance is the rate at which plasma would have to be cleared of the drug to account for the observed kinetics of change of the total amount of drug in the body, assuming that all the drug in the body is present at the same concentration as that in the plasma.(PPC.42)
意味
- クリアランス↑→物質の排出能が高い、排出されやすい、再吸収されにくい
- クリアランス↓→物質の排出能が低い、排出されにくい、再吸収されやすい
式
- 定義1～3に基づくと
- UX: Xの尿中濃度
- V : 尿量~
- PX: Xの血漿濃度~
- CX: クリアランス(前述の定義参照)
- UX･V = PX･CX
- CX= V･UX/PX
- 定義4に基づくと
- Clearance = (amount/time)/(amount/volume) = 血漿からの薬物の除去速度 / 血中薬物濃度 = 単位時間あたり尿量 x 尿中薬物濃度 / 血中薬物濃度
- 上記の式は定常状態(単位時間あたりの薬物濃度が変化しなくなった状態)における血中薬物濃度を規定する式に変形できる。定常状態では単位時間に排泄される薬物量と単位時間に取り込まれる薬物量が等しくなった状態であるから、以下の通りとなる。(PPC.44)
- 血中薬物濃度 = 血漿からの薬物の除去速度 / クリアランス = 薬物の血漿への投与速度 / クリアランス = bioavility x dose / (dosing interval x clearance)
- これによれば、同一の投与間隔でdoseを2倍量にすれば、血中濃度が2倍になるということが分かる。
備考
「elimination」
- n.
- 関
- ablation、abscission、abstract、abstraction、clearance、delete、deletion、desorption、detach、detachment、disappear、disappearance、dislodge、drain、draining、egest、egestion、eject、eliminate、emission、emit、evacuate、evacuation、exclude、exclusion、excrete、excretion、expel、export、obliteration、obviate、regress、removal、remove、scavenge
「eliminate」
- v.
- 除去する、除く、排出する、排除する、(化学)脱離する
- 関
- abscission、abstract、abstraction、clearance、delete、deletion、desorption、detach、detachment、dislodge、drain、draining、egest、egestion、eject、elimination、emission、emit、evacuate、evacuation、except、exclude、exclusion、excrete、excretion、expel、export、obliteration、obviate、removal、remove、scavenge
「exclude」
- vt.
- 締め出す、除外する、排除する(⇔include)。追放する
- 除く、落とす、抜かす
- 考慮しない、無視する。(証拠などを)取り上げない、退ける
- (可能性・見込み・疑いを)全く許さない、～の余地を与えない
「evacuation」
- n.
- 排除、除去
- 関
- abstract、abstraction、clearance、delete、deletion、dislodge、eliminate、elimination、evacuate、exclude、exclusion、obliteration、obviate、removal、remove、scavenge