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1. 全人工股関節置換術total hip arthroplasty [show details]
… which has been shown to help prevent access of wear particles from the articulating surface down along the implant-bone interface.… developed the fundamental principles of the artificial hip and is credited as the father of THA.… performed each year in the United States alone . The normal hip functions as a "ball-and-socket" joint. The femoral head (ball) articulates with the acetabulum (socket), allowing smooth range of motion …
2. 肩鎖関節障害acromioclavicular joint disorders [show details]
… cases, remains asymptomatic. The joint gradually narrows as the articular disc and chondral cartilage wear away. This degeneration is often more rapid than in other joints, with the articular disc beginning …
3. 関節保護の概要overview of joint protection [show details]
… unstable or painful joints may have a limited understanding of activities that increase the risk of further joint damage or that promote inflammation. This topic will review the concept of joint protection and …
4. 下肢の関節保護プログラムjoint protection program for the lower limb [show details]
… placing excessive stress on the joints and soft tissues, which could contribute to injury and long-term problems, especially in arthritic joints. The history of past shoe wear may be important for women with …
5. 上肢の関節保護プログラムjoint protection program for the upper limb [show details]
… instructions from a physical and/or occupational therapist. Respect pain; Wear an appropriate splint for rest and activity if joints are painful Consult an occupational therapist about work-induced problems …

English Journal

MiR-377 inhibits wear particle-induced osteolysis via targeting RANKL.

Li W, Wang X, Chang L, Wang F.
Cell biology international. 2019 Apr;().
Periprosthetic osteolysis caused by wear particles is the main factor that affects the long-term efficacy of artificial joint replacement, and macrophages play a vital role in the pathogenesis of periprosthetic osteolysis, while the potential mechanism underlying this is still unclear. To invest
PMID 30958621

Preclinical Bench Testing on a Novel Posterior Dynamic Deformity Correction Device for Scoliosis.

Arnin U, El-Hawary R, Betz RR, Lonner BS, Floman Y.
Spine deformity. 2019 03;7(2)203-212.
Biomechanical test. To summarize the preclinical tests performed to assess the durability of a novel fusionless dynamic device for the treatment of adolescent idiopathic scoliosis (AIS). The minimal invasive deformity correction (MID-C) system is a distractible posterior dynamic deformity correction
PMID 30660213

Icariin inhibits RANKL-induced osteoclastogenesis via modulation of the NF-κB and MAPK signaling pathways.

Xu Q, Chen G, Liu X, Dai M, Zhang B.
Biochemical and biophysical research communications. 2019 Jan;508(3)902-906.
The receptor activator of nuclear factor-κB (NF-κB) ligand (RANKL)-RANK regulatory axis is a major regulator of osteoclast differentiation and activation. Icariin, a flavonol glycoside isolated from the Epimedium herb, has been reported to prevents bone loss in ovariectomized mice and inhibits wea
PMID 30538045

Japanese Journal

人工関節用樹脂材料のバイオトライボロジー

澤江義則
トライボロジスト 62(7), 435-441, 2017
NAID 130005767494

H-08 人工関節軸受面への表面テクスチャリングが超高分子量ポリエチレンの摩耗に与える影響

西真生,近浦裕斗,吉岡陸,桜庭新,中島雄太,中西義孝
日本機械学会九州支部講演論文集 2016.69(0), 317-318, 2016
NAID 110010054781

2G36 人工関節摺動面から生じる超高分子量ポリエチレン摩耗粉の形態および生体反応に関する研究

吉岡陸,日垣秀彦,中西義孝,政岡晴行,近浦裕斗,西真生,中島雄太,藤原章雄,菰原義弘,竹屋元裕,水田博志
バイオエンジニアリング講演会講演論文集 2016.28(0), _2G36-1_-_2G36-5_, 2016
… Researchers have reported that there are some correlations between the morphological aspects of wear debris generated from an ultra-high molecular weight polyethylene (UHMWPE) in an artificial joint and the biological response induced by the debris. … The wear particles stimulate macrophages, and production of inflammatory cytokine may induce osteolysis, that leads to joint loosening. …
NAID 110010052249