WordNet

of critical importance and consequence; "an acute (or critical) lack of research funds"
having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
of an angle; less than 90 degrees
of or relating to the medulla of any body part
containing or consisting of or resembling bone marrow
of or relating to the medulla oblongata
the inner part of an organ or structure in plant or animal
the localized death of living cells (as from infection or the interruption of blood supply) (同)mortification, gangrene, sphacelus

PrepTutorEJDIC

(先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
〈U〉骨髄 / =medulla oblongata
壊疽(えそ)
腎臓の

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1. 急性尿細管壊死後の腎臓および患者の転帰 renal and patient outcomes after acute tubular necrosis
2. 妊娠における急性腎障害（急性腎不全） acute kidney injury acute renal failure in pregnancy
3. 虚血後（虚血性）の急性尿細管壊死の発症および病因 pathogenesis and etiology of postischemic ischemic acute tubular necrosis
4. 急性腎同種移植片拒絶反応の臨床症状および診断 clinical manifestations and diagnosis of acute renal allograft rejection
5. 鎌状赤血球症の腎症状 renal manifestations of sickle cell disease

Alhwiesh A.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.Saudi J Kidney Dis Transpl.2014 Mar;25(2):249-65.
Sickle cell disease (SCD) is a major health problem in many countries. Sickle cell nephropathy (SCN) is now a well-characterized entity with specific manifestations, risk factors and prognosis. The presence of sickled erythrocytes in the renal medullary vessels is the hallmark of the disease with a
PMID 24625990

Nephroprotective effects of TVP1022, a non-MAO inhibitor S-isomer of rasagiline, in an experimental model of diabetic renal ischemic injury.

Abu-Saleh N1, Awad H, Khamaisi M, Armaly Z, Karram T, Heyman SN, Kaballa A, Ichimura T, Holman J, Abassi Z.
American journal of physiology. Renal physiology.Am J Physiol Renal Physiol.2014 Jan 1;306(1):F24-33. doi: 10.1152/ajprenal.00379.2013. Epub 2013 Nov 6.
Ischemic acute kidney injury (iAKI) in diabetes mellitus is associated with a rapid deterioration of kidney function, more than in nondiabetic subjects. TVP1022, a non-MAO inhibitor S-isomer of rasagiline, possesses antioxidative and antiapoptotic activities. The current study examines the effects o
PMID 24197064

Losartan improved antioxidant defense, renal function and structure of postischemic hypertensive kidney.

Ivanov M1, Mihailović-Stanojević N1, Grujić Milanović J1, Jovović D1, Marković-Lipkovski J2, Cirović S2, Miloradović Z1.
PloS one.PLoS One.2014 May 5;9(5):e96353. doi: 10.1371/journal.pone.0096353. eCollection 2014.
Ischemic acute renal failure (ARF) is a highly complex disorder involving renal vasoconstriction, filtration failure, tubular obstruction, tubular backleak and generation of reactive oxygen species. Due to this complexity, the aim of our study was to explore effects of Angiotensin II type 1 receptor
PMID 24796787

Atrial natriuretic peptide enhances recovery from ischemia/reperfusion-induced renal injury in rats(GENETICS, MOLECULAR BIOLOGY, AND GENE ENGINEERING)

Chujo Kousuke,Ueno Masaki,Asaga Takehiko [他],Sakamoto Haruhiko,Shirakami Gotaro,Ueki Masaaki
Journal of bioscience and bioengineering 109(6), 526-530, 2010-06
… Recovery from ischemic acute kidney injury requires the replacement of damaged tubular cells. … This repair process involves epidermal growth factor (EGF) synthesized in medullary the thick ascending limbs (mTAL) of Henle. … Atrial natriuretic peptide (ANP), a hormone synthesized by the cardiac atria, increases glomerular filtration rate and renal medullary blood flow. …
NAID 110007641895

Tempol Protects against Ischemic Acute Renal Failure by Inhibiting Renal Noradrenaline Overflow and Endothelin-1 Overproduction(Pharmacology)

Fujii Toshihide,Takaoka Masanori,Ohkita Mamoru [他],MATSUMURA Yasuo
Biological & pharmaceutical bulletin 28(4), 641-645, 2005-04-01
… The effects of tempol, a superoxide dismutase mimetic, on ischemia/reperfusion-induced acute renal failure (ARF), noradrenaline (NA) overflow and endothelin-1 (ET-1) overproduction in rats were examined. … Ischemic ARF was induced by occlusion of the left renal artery and vein for 45 min followed by reperfusion, 2 weeks after contralateral nephrectomy. …
NAID 10016662131

Dietary Supplementation of L-Carnosine Prevents Ischemia/Reperfusion-Induced Renal Injury in Rats(Pharmacology)

Fujii Toshihide,Takaoka Masanori,Tsuruoka Nobuo [他],KISO Yoshinobu,TANAKA Takaharu,MATSUMURA Yasuo
Biological & pharmaceutical bulletin 28(2), 361-363, 2005-02-01
… The effects of dietary supplementation of L-carnosine (β-alanyl-_L -histidine) on ischemia/reperfusion-induced acute renal failure (ARF) in rats were examined. … Ischemic ARF was induced by occlusion of the left renal artery and vein for 45 min followed by reperfusion, 2 weeks after contralateral nephrectomy. …
NAID 10016660405