acute B-cell leukemia

急性B細胞白血病

関

B-ALL、B-cell acute lymphoblastic leukemia、B-cell acute lymphocytic leukemia、Burkitt lymphoma、Burkitt tumor、Burkitt's leukemia、Burkitt's lymphoma、Burkitt's tumor

WordNet

1. of critical importance and consequence; "an acute (or critical) lack of research funds"
2. having or demonstrating ability to recognize or draw fine distinctions; "an acute observer of politics and politicians"; "incisive comments"; "icy knifelike reasoning"; "as sharp and incisive as the stroke of a fang"; "penetrating insight"; "frequent penetrative observations" (同)discriminating, incisive, keen, knifelike, penetrating, penetrative, piercing, sharp
3. extremely sharp or intense; "acute pain"; "felt acute annoyance"; "intense itching and burning" (同)intense
4. having or experiencing a rapid onset and short but severe course; "acute appendicitis"; "the acute phase of the illness"; "acute patients"
5. of an angle; less than 90 degrees
6. small room in which a monk or nun lives (同)cubicle
7. a device that delivers an electric current as the result of a chemical reaction (同)electric cell
8. a room where a prisoner is kept (同)jail cell, prison cell
9. (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
10. any small compartment; "the cells of a honeycomb"
11. a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
12. the 2nd letter of the Roman alphabet (同)b
13. the blood group whose red cells carry the B antigen (同)type_B, group B
14. malignant neoplasm of blood-forming tissues; characterized by abnormal proliferation of leukocytes; one of the four major types of cancer (同)leukaemia, leucaemia, cancer of the blood

PrepTutorEJDIC

1. (先の)『鋭い』,とがった / (痛み・感情などが)『激しい』,強い / (知力・感覚などが)『鋭い』,鋭敏な / (事態が)重大な / (病気が)急性の / (音が)高い,鋭い / 鋭角の
2. (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
3. 白血病

UpToDate Contents

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• 1. 急性骨髄性白血病の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of acute myeloid leukemia
• 2. 小児および思春期における急性リンパ芽球性白血病の症状および診断の概要 overview of the presentation and diagnosis of acute lymphoblastic leukemia in children and adolescents
• 3. 家族性急性白血病および骨髄異形成症候群 familial acute leukemia and myelodysplastic syndromes
• 4. 急性骨髄性白血病の合併症の概要 overview of the complications of acute myeloid leukemia
• 5. 小児および思春期における急性リンパ芽球性白血病の治療の概要 overview of the treatment of acute lymphoblastic leukemia in children and adolescents

English Journal

• The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation.

• de Laurentiis A1, Hiscott J2, Alcalay M1,3.
• Oncogene.Oncogene.2015 Dec 3;34(49):6018-28. doi: 10.1038/onc.2015.50. Epub 2015 Apr 20.
• The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene. Many studies on TEL-AML1 describe specific properties of the fusion protein, but a thorough understanding of its function is lacking. We exp
• PMID 25893288

• Infection Exposure Is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.

• Martín-Lorenzo A1, Hauer J2, Vicente-Dueñas C1, Auer F2, González-Herrero I1, García-Ramírez I1, Ginzel S3, Thiele R4, Constantinescu SN5, Bartenhagen C6, Dugas M6, Gombert M2, Schäfer D2, Blanco O7, Mayado A8, Orfao A8, Alonso-López D9, Rivas Jde L10, Cobaleda C11, García-Cenador MB12, García-Criado FJ12, Sánchez-García I13, Borkhardt A14.
• Cancer discovery.Cancer Discov.2015 Dec;5(12):1328-43. doi: 10.1158/2159-8290.CD-15-0892. Epub 2015 Sep 25.
• Earlier in the past century, infections were regarded as the most likely cause of childhood B-cell precursor acute lymphoblastic leukemia (pB-ALL). However, there is a lack of relevant biologic evidence supporting this hypothesis. We present in vivo genetic evidence mechanistically connecting inheri
• PMID 26408659

• Hypereosinophilia in Acute Lymphoblastic Leukemia: Two Cases with Review of Literature.

• Sahu KK1, Malhotra P1, Khadwal A1, Sachdeva MS2, Sharma P2, Varma N2, Varma SC1.
• Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion.Indian J Hematol Blood Transfus.2015 Dec;31(4):460-5. doi: 10.1007/s12288-014-0436-7. Epub 2014 Jul 30.
• Eosinophilia is rare in acute leukemia at presentation. Discrete reports and case studies in recent years have created significant interest in the field of "Acute leukemia with eosinophilia". We herein present two cases of eosinophilia in association with acute lymphoblastic leukemia with brief revi
• PMID 26306071

Japanese Journal

• 新規抗体/薬物複合体によるリンパ系腫瘍の治療 : イノツズマブ・オゾガマイシンとブレンツキシマブ・ベドチン (特集 新規ターゲットおよび医薬品による血液がん治療の新たな展開)

• 薄井 紀子
• 血液内科 70(2), 186-191, 2015-02
• NAID 40020385039

• 小児Ph-like急性リンパ芽球性白血病の臨床的および細胞遺伝学的特徴

• 清河 信敬
• 血液内科 69(2), 274-278, 2014-08
• NAID 40020181861

• A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation.

• Nagai Yuya,Kawahara Masahiro,Sugino Noriko,Shimazu Yayoi,Hishizawa Masakatsu,Yamashita Kouhei,Kadowaki Norimitsu,Takaori-Kondo Akifumi
• Experimental hematology & oncology 3(1), 2014-02-17
• … Here we report on a case of Philadelphia chromosome positive B lymphoblastic leukemia (Ph+ALL), which developed following a long duration of essential thrombocythemia (ET). … The minor BCR-ABL1 fusion was detected not only in the CD34+CD19+ population but also in HSPCs and granulocytes, indicating that the Philadelphia chromosome was acquired in an early hematopoietic stage at least prior to the commitment to B cell development. …
• NAID 120005411358

Related Links

• Acute Lymphoblastic Leukemia: Survival, Treatments, and More

WebMD explains acute lymphoblastic leukemia (ALL) including its symptoms, risk factors, and treatments. ... Acute lymphoblastic leukemia (ALL) is a type of blood cancer. Also known as acute lymphocytic leukemia or acute ...

• B-Cell Acute Lymphoblastic Leukemia for Adults: Symptoms ...

WebMD explains the causes, symptoms, and treatment of B-cell acute lymphoblastic leukemia, a cancer that affects your ... B-Cell Acute Lymphoblastic Leukemia for Adults What Is B-Cell Acute Lymphoblastic ...

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★リンクテーブル★

リンク元	「B-ALL」「B-cell acute lymphoblastic leukemia」「Burkitt's leukemia」「B-cell acute lymphocytic leukemia」「急性B細胞白血病」
関連記事	「B」「acute」「cell」

「B-ALL」

　　[★]

B細胞性急性リンパ性白血病、B細胞急性リンパ球性白血病

関

acute B-cell leukemia、B-cell acute lymphoblastic leukemia、B-cell acute lymphocytic leukemia、Burkitt lymphoma、Burkitt tumor、Burkitt's leukemia、Burkitt's lymphoma、Burkitt's tumor

「B-cell acute lymphoblastic leukemia」

　　[★]

B細胞性急性リンパ性白血病、B細胞急性リンパ球性白血病

関

acute B-cell leukemia、B-ALL、B-cell acute lymphocytic leukemia、Burkitt lymphoma、Burkitt tumor、Burkitt's leukemia、Burkitt's lymphoma、Burkitt's tumor

「Burkitt's leukemia」

　　[★]

バーキット白血病、Burkitt白血病

関

acute B-cell leukemia、B-ALL、B-cell acute lymphoblastic leukemia、B-cell acute lymphocytic leukemia、Burkitt lymphoma、Burkitt tumor、Burkitt's lymphoma、Burkitt's tumor

「B-cell acute lymphocytic leukemia」

　　[★]

B細胞性急性リンパ性白血病

関

acute B-cell leukemia、B-ALL、B-cell acute lymphoblastic leukemia、Burkitt lymphoma、Burkitt tumor、Burkitt's leukemia、Burkitt's lymphoma、Burkitt's tumor

「急性B細胞白血病」

　　[★]

英

acute B-cell leukemia

関

B細胞急性リンパ球性白血病、バーキットリンパ腫、バーキット腫瘍、B細胞性急性リンパ性白血病、バーキット白血病

「B」

　　[★]

• 気管分岐部下緑
• 補体のalternative pathwayに関わる蛋白質

• Mg2+存在下でC3, B, Dが反応してC3bBbとなり、これがC3転換酵素(C3bBb)あるいはC5転換酵素(C3bBb3b)を形成する。これらはP(properdin)と結合して活性化し、それぞれC3、C5を活性化する

　 　

「acute」

　　[★]

• adj.

• (疾患)急性の、急性型の、急性的な。(形状が)鋭い、鋭角の。(感覚、才知などが)鋭い。明敏な、鋭い眼識のある。

関

acutely、quick、sharp

　 　 　 　 　 　

「cell」

　　[★] 細胞