- 関
- mitogen-activated protein kinase kinase 6
WordNet
- make a map of; show or establish the features of details of; "map the surface of Venus"
- to establish a mapping (of mathematical elements or sets) (同)represent
- a diagrammatic representation of the earths surface (or part of it)
- plan, delineate, or arrange in detail; "map ones future" (同)map out
- depict as if on a map; "sorrow was mapped on the mothers face"
- explore or survey for the purpose of making a map; "We havent even begun to map the many galaxies that we know exist"
- locate within a specific region of a chromosome in relation to known DNA or gene sequences; "map the genes"
- the 13th letter of the Roman alphabet (同)m
- an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
PrepTutorEJDIC
- (1枚1枚の)『地図』;天体図 / …‘の'地図を作る;…‘を'地図にかく
- Mach number / mark[s] / Monsieur
- Massachusetts / mental age
UpToDate Contents
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English Journal
- Fragment-based drug discovery of potent and selective MKK3/6 inhibitors.
- Adams M1, Kobayashi T2, Lawson JD3, Saitoh M2, Shimokawa K2, Bigi SV1, Hixon MS4, Smith CR1, Tatamiya T2, Goto M2, Russo J5, Grimshaw CE3, Swann S1.
- Bioorganic & medicinal chemistry letters.Bioorg Med Chem Lett.2016 Feb 1;26(3):1086-9. doi: 10.1016/j.bmcl.2015.11.054. Epub 2015 Nov 17.
- The MAPK signaling cascade, comprised of several linear and intersecting pathways, propagates signaling into the nucleus resulting in cytokine and chemokine release. The Map Kinase Kinase isoforms 3 and 6 (MKK3 and MKK6) are responsible for the phosphorylation and activation of p38, and are hypothes
- PMID 26704264
- Two hydrophobic residues can determine the specificity of mitogen-activated protein kinase docking interactions.
- Bardwell AJ1, Bardwell L2.
- The Journal of biological chemistry.J Biol Chem.2015 Oct 30;290(44):26661-74. doi: 10.1074/jbc.M115.691436. Epub 2015 Sep 14.
- MAPKs bind to many of their upstream regulators and downstream substrates via a short docking motif (the D-site) on their binding partner. MAPKs that are in different families (e.g. ERK, JNK, and p38) can bind selectively to D-sites in their authentic substrates and regulators while discriminating a
- PMID 26370088
- Overexpression of prohibitin-1 inhibits RANKL-induced activation of p38-Elk-1-SRE signaling axis blocking MKK6 activity.
- Lee CH1, Choi SW2, Kim JY3, Kim SH2, Yoon KH4, Oh J5, Lee MS6.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Aug 7;463(4):1028-33. doi: 10.1016/j.bbrc.2015.06.053. Epub 2015 Jun 12.
- Prohibitin-1 (PHB) regulates diverse cellular processes by controlling several signaling pathways. In this study, we investigated the functional involvement of PHB in osteoclast differentiation. PHB expression was time-dependently increased by RANKL in BMMs. However, the retroviral over-expression o
- PMID 26079882
Japanese Journal
- Macrophage-stimulating activities of newly isolated complex polysaccharides from Parachlorella kessleri strain KNK-A001
- International Journal of Biological Macromolecules 104, 400-406, 2017-11
- NAID 120006318835
- BMP7 dose‐dependently stimulates proliferation and cadherin‐11 expression via ERK and p38 in a murine metanephric mesenchymal cell line
- Antagonistic Interactions between Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase and Retinoic Acid Receptor Signaling in Colorectal Cancer Cells
Related Links
- Negative feedback regulation of MKK6 mRNA stability by p38alpha mitogen- activated protein kinase [4]. ... Moreover, we show that the MKK6 mRNA is more stable in p38alpha(-/-) cells and that the 3'untranslated region of this mRNA can ...
★リンクテーブル★
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- 英
- MAP kinase kinase 6
- 関
- マイトジェン活性化プロテインキナーゼキナーゼ6
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マイトジェン活性化プロテインキナーゼキナーゼ6
- 関
- MAP kinase kinase 6
[★]
- 地図で表す、(遺伝子などを)位置づける、(遺伝子などが)位置する
- 関
- lie、locate、location、loci、locus、mapping、position、rank、sit、situated、situation、stand、topo
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キナーゼ カイネース リン酸化酵素 phosphoenzyme phosphotransferase
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メチオニン methionine