カーリー線
WordNet
- mark with lines; "sorrow had lined his face"
- a length (straight or curved) without breadth or thickness; the trace of a moving point
- a single frequency (or very narrow band) of radiation in a spectrum
- reinforce with fabric; "lined books are more enduring"
- a particular kind of product or merchandise; "a nice line of shoes" (同)product line, line of products, line of merchandise, business line, line of business
- the road consisting of railroad track and roadbed (同)railway line, rail line
- a commercial organization serving as a common carrier
- acting in conformity; "in line with"; "he got out of line"; "toe the line"
- something (as a cord or rope) that is long and thin and flexible; "a washing line"
- a conceptual separation or distinction; "there is a narrow line between sanity and insanity" (同)dividing_line, demarcation, contrast
- a formation of people or things one behind another; "the line stretched clear around the corner"; "you must wait in a long line at the checkout counter"
- a formation of people or things one beside another; "the line of soldiers advanced with their bayonets fixed"; "they were arrayed in line of battle"; "the cast stood in line for the curtain call"
- a fortified position (especially one marking the most forward position of troops); "they attacked the enemys line"
- a mark that is long relative to its width; "He drew a line on the chart"
- a spatial location defined by a real or imaginary unidimensional extent
- in games or sports; a mark indicating positions or bounds of the playing area
- persuasive but insincere talk that is usually intended to deceive or impress; "`let me show you my etchings is a rather worn line"; "he has a smooth line but I didnt fall for it"; "that salesman must have practiced his fast line of talk"
- text consisting of a row of words written across a page or computer screen; "the letter consisted of three short lines"; "there are six lines in every stanza"
- be in line with; form a line along; "trees line the riverbank" (同)run along
- cover the interior of; "line the gloves"; "line a chimney"
- fill plentifully; "line ones pockets"
- providing something with a surface of a different material (同)facing
- a protective covering that protects an inside surface (同)liner
- the act of attaching an inside lining (to a garment or curtain etc.)
- having a lining or a liner; often used in combination; "a lined skirt"; "a silk-lined jacket"
- (used especially of skin) marked by lines or seams; "their lined faces were immeasurably sad"; "a seamed face" (同)seamed
- bordered by a line of things; "tree lined streets"
- Chinese distance measure; approximately 0.5 kilometers
PrepTutorEJDIC
- 『線』,筋,けい / (色・縫い目などの)『線』,しま;(顔・手などの)しわ(wrinkle) / (物・人の)『列』,行列(row) / 『綱』,糸,針金 / 電線,電話線,電信線 / (文章の)『行』;(詩の)『行』 / 《しばしばa~》《話》『短い手紙』(note) / 《複数形で》輪郭,外形(outline) / 境界線(boundary);限界,限度(limit) / (鉄道・バスなどの)路線;航路,空路 / 《複数形で》せりふ / 進路,道順(course);(考えなどの)筋道,方針 / 《しばしばone's~》(活動の)分野,方面;特意 / 家系,血統,血筋 / 在庫商品,仕入れ品 / 導管,パイプライン / 《しばしば複数形で》戦線,防御線 / …‘に'『線を引く』,筋(しま,しわ)をつける / …‘に'『沿って並ぶ;』(…を)…‘に'沿って並べる《+『名』+『with』+『名』》
- (材料で)〈着物など〉‘に'裏を付ける《+『名』『with』+『名』》 / (…で)…‘を'満たす,(…を)…‘に'詰め込む《+『名』+『with』+『名』》
- 〈U〉(服などの)裏張り,裏塗り / 〈U〉裏地,裏材
UpToDate Contents
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English Journal
- Differential Genetic and Epigenetic Regulation of catechol-O-methyltransferase is Associated with Impaired Fear Inhibition in Posttraumatic Stress Disorder.
- Norrholm SD1, Jovanovic T, Smith AK, Binder E, Klengel T, Conneely K, Mercer KB, Davis JS, Kerley K, Winkler J, Gillespie CF, Bradley B, Ressler KJ.Author information 1Mental Health Service Line, Atlanta VA Medical Center Decatur, GA, USA ; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine Atlanta, GA, USA.AbstractThe catechol-O-methyltransferase (COMT) enzyme is critical for the catabolic regulation of synaptic dopamine, resulting in altered cortical functioning. The COMT Val(158)Met polymorphism has been implicated in human mental illness, with Met/Met homozygotes associated with increased susceptibility to posttraumatic stress disorder (PTSD). Our primary objective was to examine the intermediate phenotype of fear inhibition in PTSD stratified by COMT genotype (Met/Met, Val/Met, and Val/Val) and differential gene regulation via methylation status at CpG sites in the COMT promoter region. More specifically, we examined the potential interaction of COMT genotype and PTSD diagnosis on fear-potentiated startle during fear conditioning and extinction and COMT DNA methylation levels (as determined using genomic DNA isolated from whole blood). Participants were recruited from medical and gynecological clinics of an urban hospital in Atlanta, GA, USA. We found that individuals with the Met/Met genotype demonstrated higher fear-potentiated startle to the CS- (safety signal) and during extinction of the CS+ (danger signal) compared to Val/Met and Val/Val genotypes. The PTSD+ Met/Met genotype group had the greatest impairment in fear inhibition to the CS- (p = 0.006), compared to Val carriers. In addition, the Met/Met genotype was associated with DNA methylation at four CpG sites, two of which were associated with impaired fear inhibition to the safety signal. These results suggest that multiple differential mechanisms for regulating COMT function - at the level of protein structure via the Val(158)Met genotype and at the level of gene regulation via differential methylation - are associated with impaired fear inhibition in PTSD.
- Frontiers in behavioral neuroscience.Front Behav Neurosci.2013 Apr 10;7:30. doi: 10.3389/fnbeh.2013.00030. eCollection 2013.
- The catechol-O-methyltransferase (COMT) enzyme is critical for the catabolic regulation of synaptic dopamine, resulting in altered cortical functioning. The COMT Val(158)Met polymorphism has been implicated in human mental illness, with Met/Met homozygotes associated with increased susceptibility to
- PMID 23596403
- Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice.
- Michaud EJ1, Culiat CT, Klebig ML, Barker PE, Cain KT, Carpenter DJ, Easter LL, Foster CM, Gardner AW, Guo ZY, Houser KJ, Hughes LA, Kerley MK, Liu Z, Olszewski RE, Pinn I, Shaw GD, Shinpock SG, Wymore AM, Rinchik EM, Johnson DK.Author information 1Life Sciences Division, Oak Ridge National Laboratory, P,O, Box 2008, Oak Ridge, TN 37831, USA. michaudejiii@ornl.govAbstractBACKGROUND: Analysis of an allelic series of point mutations in a gene, generated by N-ethyl-N-nitrosourea (ENU) mutagenesis, is a valuable method for discovering the full scope of its biological function. Here we present an efficient gene-driven approach for identifying ENU-induced point mutations in any gene in C57BL/6J mice. The advantage of such an approach is that it allows one to select any gene of interest in the mouse genome and to go directly from DNA sequence to mutant mice.
- BMC genomics.BMC Genomics.2005 Nov 21;6:164.
- BACKGROUND: Analysis of an allelic series of point mutations in a gene, generated by N-ethyl-N-nitrosourea (ENU) mutagenesis, is a valuable method for discovering the full scope of its biological function. Here we present an efficient gene-driven approach for identifying ENU-induced point mutations
- PMID 16300676
- Participation in operation starting line, experience of negative emotions, and incidence of negative behavior.
- Kerley KR1, Matthews TL, Schulz JT.Author information 1Department of Sociology, Mississippi State University, P.O. Box C, Mississippi State, MS 39762, USA. kerley@soc.msstate.eduAbstractThe prison industry in the United States has experienced an unprecedented period of growth during the past three decades. Growing dissatisfaction with the monetary investment in the criminal justice system, state-level budget constraints, and high recidivism rates have led many criminal justice professionals to rethink issues of offender resocialization and rehabilitation. Faith-based prison programs are increasingly being used as inexpensive methods for potentially improving the institutional behavior of inmates and reducing their likelihood of postrelease arrest. Unfortunately, however, there is little systematic research on this issue. Using data from Mississippi's largest state prison, the authors explore the relationship between participation in the faith-based prison event, Operation Starting Line, and subsequent experience of negative emotions and incidence of negative behaviors. Descriptive results suggest modest, yet positive, effects of attendance at the event. The article concludes with comments about the potential efficacy of faith-based prison programs and suggestions for future research.
- International journal of offender therapy and comparative criminology.Int J Offender Ther Comp Criminol.2005 Aug;49(4):410-26.
- The prison industry in the United States has experienced an unprecedented period of growth during the past three decades. Growing dissatisfaction with the monetary investment in the criminal justice system, state-level budget constraints, and high recidivism rates have led many criminal justice prof
- PMID 15983055
Japanese Journal
- 薬剤師が知っておくべき臓器別画像解析の基礎知識(5)1.呼吸器分野(5)間質性肺疾患の画像診断--Radiologic-Anatomic-Pathologic Correlation
- X線写真で読みとる胸部の異常(9)肺水腫と似て非なり--好酸球性肺炎
- アセチレンガス吸入により発症したと考えられる急性好酸球性肺炎の1例
- 高見澤 明美,甘利 俊哉,久保 惠嗣
- 日本呼吸器学会雑誌 = The journal of the Japanese Respiratory Society 38(12), 947-951, 2000-12-10
- NAID 10006830074
Related Links
- 心不全の胸部CTですが肺の最外層のラインは 矢印された部分だけでなく、他にも結構な数 ありそうですね。全部矢印して頂けると、 理解しやすいです。そうでないと、他の ラインは違うのかなと思い。頭が混乱してきます。
- ①Kerley line Kerley line は肥厚した小葉間隔壁を表し、肺野に見られる線状影でその部位・長さ・走行によってA・B・Cの3つのラインがある。 急性・一過性では肺水腫 が、慢性では僧帽弁狭窄症・癌性リンパ管症などのリンパ流路の障害 ...
Related Pictures
★リンクテーブル★
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- 英
- Kerley's line, Kerley line, Kerley lines
- 同
- Kerley線
- 下肺野の胸側部に胸膜面に接して存在し、1cm程度の水平に走る影
- 小葉間隔壁の肥厚 ← 間質性肺水腫など
[★]
- 日
- 長い散在反復配列、長散在型反復配列、長い散在性反復配列、ライン、広範囲散在反復配列
- 英
- long interspersed nuclear element, long interspersed nucleotide element, long interspersed element, long interspersed repetitive elements, LINEs, long interspersed repeat sequences
- 関
- レトロトランスポゾン
- quoted from http://en.wikipedia.org/wiki/Long_interspersed_nucleotide_elements#LINEs
- Long interspersed nuclear elements[8] are a group of genetic elements that are found in large numbers in eukaryotic genomes. They are transcribed (or are the evolutionary remains of what was once transcribed) to an RNA using an RNA polymerase II promoter that resides inside the LINE. LINEs code for the enzyme reverse transcriptase, and many LINEs also code for an endonuclease (e.g. RNase H). The reverse transcriptase has a higher specificity for the LINE RNA than other RNA, and makes a DNA copy of the RNA that can be integrated into the genome at a new site.
- The 5' UTR contains the promoter sequence, while the 3' UTR contains a polyadenylation signal (AATAAA) and a poly-A tail.[10] Because LINEs move by copying themselves (instead of moving, like transposons do), they enlarge the genome. The human genome, for example, contains about 20,000-40,000 LINEs, which is roughly 21% of the genome.
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- 関
- lineage、lining、pedigree、stock、strain、string、undercoat
[★]
- 関
- line、undercoat