IGF-binding protein

• IGF結合タンパク質

関

IGFBP、insulin-like growth factor binding protein

WordNet

1. executed with proper legal authority; "a binding contract"
2. the protective covering on the front, back, and spine of a book; "the book had a leather binding" (同)book binding, cover, back
3. strip sewn over or along an edge for reinforcement or decoration
4. the capacity to attract and hold something
5. any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
6. the 9th letter of the Roman alphabet (同)i

PrepTutorEJDIC

1. 義務的な,拘束力ある / 〈U〉しばること;〈C〉しばる物 / 〈C〉製本,装丁 / 〈U〉縁(‘ふち')取り材料
2. 蛋白(たんばく)質
3. 『私は』私が
4. iodineの化学記号

UpToDate Contents

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• 1. インスリン様成長因子 Iの生理学 physiology of insulin like growth factor i
• 2. 低身長に対する診断的アプローチ diagnostic approach to short stature
• 3. 成長ホルモン不感受性症候群 growth hormone insensitivity syndromes
• 4. 前期破水による早産 preterm premature rupture of membranes
• 5. 先端巨大症の診断 diagnosis of acromegaly

English Journal

• HIV-1 Tat binds to SH3 domains: Cellular and viral outcome of Tat/Grb2 interaction.

• Rom S, Pacifici M, Passiatore G, Aprea S, Waligorska A, Del Valle L, Peruzzi F.SourceTemple University School of Medicine, Department of Pathology and Laboratory Medicine, Philadelphia, PA, USA.
• Biochimica et biophysica acta.Biochim Biophys Acta.2011 Oct;1813(10):1836-44. Epub 2011 Jul 1.
• The Src-homology 3 (SH3) domain is one of the most frequent protein recognition modules (PRMs), being represented in signal transduction pathways and in several pathologies such as cancer and AIDS. Grb2 (growth factor receptor-bound protein 2) is an adaptor protein that contains two SH3 domains and
• PMID 21745501

• Annexin VI is a mannose-6-phosphate-independent endocytic receptor for bovine β-glucuronidase.

• Ramirez-Mata A, Michalak C, Mendoza-Hernandez G, Leon-Del-Rio A, Gonzalez-Noriega A.SourceDepartment of Cell Biology and Physiology, Instituto de Investigaciones Biomedicas, Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, D.F. 04510, Mexico.
• Experimental cell research.Exp Cell Res.2011 Oct 1;317(16):2364-73. Epub 2011 Jun 6.
• Endocytosis and transport of bovine liver β-glucuronidase to lysosomes in human fibroblasts are mediated by two receptors: the well-characterized cation-independent mannose 6-phosphate receptor (IGF-II/Man6PR) and an IGF-II/Man6PR-independent receptor, which recognizes a Ser-Trp*-Ser sequence prese
• PMID 21672540

Japanese Journal

• Circulating salmon 41-kDa insulin-like growth factor binding protein (IGFBP) is not IGFBP-3 but an IGFBP-2 subtype

• Shimizu Munetaka,Suzuki Seira,Horikoshi Moeri,Hara Akihiko,Dickhoff Walton W.
• General and Comparative Endocrinology 171(3), 326-331, 2011-05-01
• … In vertebrates, most circulating insulin-like growth factor (IGF) is bound to multiple forms of IGF-binding proteins (IGFBPs) that differ both structurally and functionally. … In mammals, the largest reservoir of IGF in the circulation comes from a large (150kDa) ternary complex comprised of IGF bound to IGFBP-3, which is bound to an acid label subunit (ALS), and this variant of IGFBP is regulated by growth hormone (GH) and feed intake. …
• NAID 120002973854

• 低酸素による心筋細胞Insulin-like growth factor-1遺伝子発現亢進の役割--心保護作用の機序について

• Katoh Chisato,Osanai Tomohiro,Shibutani Shuji,Hanada Kenji,Okumura Ken
• 弘前醫學 60(1/2/3/4), 36-44, 2009
• … Insulin-like growth factor （IGF）-1 is known to exert benefi cial eff ects on the heart, but its source andfunction under hypoxia are unknown. … We investigated the eff ect of hypoxia on IGF-1 expression and its role in theregeneration in the heart. … mRNA of IGF-1, IGF-binding protein 3 （IGFBP3）, and vascular endothelial growth factor-A（VEGF-A） was measured by real-time PCR. …
• NAID 110007079178

Related Links

• Insulin-like growth factor-binding protein - Wikipedia, the free ...

Approximately 98% of IGF-1 is always bound to one of 6 binding proteins (IGF-BP ). IGFBP-3, the most abundant protein, accounts for 80% of all IGF binding. IGF-1 binds to IGFBP-3 in a 1:1 molar ratio. IGF-BP also binds to IGF-1 inside the liver ...

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★リンクテーブル★

リンク元	「IGFBP」
関連記事	「binding」「I」「binding protein」「IGF」

「IGFBP」

　　[★]

• インスリン様増殖因子結合タンパク質、インスリン様成長因子結合タンパク質

関

IGF-binding protein、insulin-like growth factor binding protein

関

IGF binding protein

「binding」

　　[★]

• n.

• 結合、バインディング

• adj.

• 結合性の

関

affinity、associate、bind、bond、bonding、combine、conjoin、conjugate、conjugation、conjunction、connect、connection、connective、connectivity、couple、dock、engage、engagement、join、ligate、linkage、symphysial、symphysic、union

　 　 　 　 　

「I」

　　[★]

• イソロイシン isoleucine
• イノシン inosine
• 阻害剤 inhibitor
• iodine
• ヨード iodide
• I因子 factor I

　 　 　

「binding protein」

　　[★]

• 結合タンパク質、結合タンパク、結合蛋白質、結合蛋白

関

BP、carrier protein、transport protein

「IGF」

　　[★]

• インスリン様増殖因子 インスリン様成長因子 insulin-like growth factor