ヒト免疫不全症ウイルス1型逆転写酵素
WordNet
- of the transmission gear causing backward movement in a motor vehicle; "in reverse gear"
- a relation of direct opposition; "we thought Sue was older than Bill but just the reverse was true" (同)contrary, opposite
- the gears by which the motion of a machine can be reversed (同)reverse gear
- the side of a coin or medal that does not bear the principal design (同)verso
- (American football) a running play in which a back running in one direction hands the ball to a back running in the opposite direction
- an unfortunate happening that hinders or impedes; something that is thwarting or frustrating (同)reversal, setback, blow, black_eye
- the 8th letter of the Roman alphabet (同)h
- a lapel on a womans garment; turned back to show the reverse side (同)revere
- turned inside out and resewn; "the reversed collar looked as good as new"
- the enzyme that copies DNA into RNA (同)RNA_polymerase
PrepTutorEJDIC
- (位置・方向・順序などにおいて)『逆の』;裏側の』 / 逆に動かす(動く),バックの / 〈U〉《the reverse》(…の)『反対』,『逆』《+『of』+『名』(『wh』‐節)》》 / 〈U〉《the reverse》(貨幣・メダルなどの)『裏側』,(一般に)(…の)裏面《+『of』+『名』》 / 〈C〉(運命などの)逆転,不運 / 〈U〉後退[装置],逆転[装置] / …‘を'『逆にする』,反対にする;…‘を'裏返す / 〈機械など〉‘を'逆転させる,逆方向に動かす / 〈判決など〉‘を'取り消す,破棄する / (ダンスで)逆に回る / 〈機械などが〉逆方向に動く
- hydrogenの化学記号
- 鉛筆の硬度 / 《俗》heroin
- （フランス語）(えりの)裏出し,折り返し
- 逆にした,反対の,裏返のし;取り消された
UpToDate Contents
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English Journal
- Structures of HIV-1 RT-RNA/DNA ternary complexes with dATP and nevirapine reveal conformational flexibility of RNA/DNA: insights into requirements for RNase H cleavage.
- Das K1, Martinez SE1, Bandwar RP1, Arnold E2.
- Nucleic acids research.Nucleic Acids Res.2014 Aug 1;42(12):8125-37. doi: 10.1093/nar/gku487. Epub 2014 May 31.
- In synthesizing a double-stranded DNA from viral RNA, HIV-1 reverse transcriptase (RT) generates an RNA/DNA intermediate. RT also degrades the RNA strand and synthesizes the second DNA strand. The RNase H active site of RT functions as a nuclease to cleave the RNA strand; however, the structural bas
- PMID 24880687
- Structure of a Dihydroxycoumarin Active-Site Inhibitor in Complex with the RNase H Domain of HIV-1 Reverse Transcriptase and Structure-Activity Analysis of Inhibitor Analogs.
- Himmel DM1, Myshakina NS2, Ilina T3, Van Ry A4, Ho WC5, Parniak MA6, Arnold E7.
- Journal of molecular biology.J Mol Biol.2014 Jul 15;426(14):2617-31. doi: 10.1016/j.jmb.2014.05.006. Epub 2014 May 17.
- Human immunodeficiency virus (HIV) encodes four essential enzymes: protease, integrase, reverse transcriptase (RT)-associated DNA polymerase, and RT-associated ribonuclease H (RNase H). Current clinically approved anti-AIDS drugs target all HIV enzymatic activities except RNase H, which has proven t
- PMID 24840303
- Enhanced Antiretroviral Therapy in Rhesus Macaques Improves RT-SHIV Viral Decay Kinetics.
- North TW1, Villalobos A2, Hurwitz SJ3, Deere JD4, Higgins J4, Chatterjee P3, Tao S3, Kauffman RC4, Luciw PA4, Kohler JJ3, Schinazi RF5.
- Antimicrobial agents and chemotherapy.Antimicrob Agents Chemother.2014 Jul;58(7):3927-3933. Epub 2014 Apr 28.
- Using an established nonhuman primate model, rhesus macaques were infected intravenously with a chimeric simian immunodeficiency virus (SIV) consisting of SIVmac239 with the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase from clone HXBc2 (RT-SHIV). The impacts of two enhanced (fou
- PMID 24777106
Japanese Journal
- Differential responses of human hepatocytes to the non-nucleoside HIV-1 reverse transcriptase inhibitor nevirapine
- Fang Jia-Long,Beland Frederick A.
- The Journal of toxicological sciences : an official journal of the Japanese Society of Toxicology 38(5), 741-752, 2013-10
- NAID 40019829046
- Development and application of a simple LC-MS method for the determination of plasma rilpivirine (TMC-278) concentrations
- Shibata Masaaki,Takahashi Masaaki,Yoshino Munehiro,Kuwahara Takeshi,Nomura Toshiharu,Yokomaku Yoshiyuki,Sugiura Wataru
- The journal of medical investigation : JMI 60(1-2), 35-40, 2013-02
- … Rilpivirine (TMC-278) is a second-generation non-nucleoside reverse transcriptase inhibitor that is high potent against both wild-type and drug-resistant HIV-1 strains. … Therefore, rilpivirine is expected to treat therapy-experienced patients who failed to use current drugs due to the emergence of drug-resistant HIV mutants. …
- NAID 120005380899
- Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase for use in cDNA synthesis.
- Konishi Atsushi,Shinomura Mayu,Yasukawa Kiyoshi
- Applied biochemistry and biotechnology 169(1), 77-87, 2013-01
- … The aim of this study is to explore the advantages of using human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) in cDNA synthesis. …
- NAID 120005241449
Related Links
- I. Introduction The retrovirus HIV, and its subsequent progression to AIDS, is a rapidly growing worldwide epidemic. HIV-1 reverse transcriptase is one of the key players in the mechanism of infection by this retrovirus. The ...
- reverse transcriptase /re·verse tran·scrip·tase/ (re-vers´ tran-skrip´tās) an enzyme that catalyzes the template-directed, step-by-step addition of deoxyribonucleotides to the end of a DNA or RNA primer or growing DNA chain, using a ...
★リンクテーブル★
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- 英
- human immunodeficiency virus type 1 reverse transcriptase, human immunodeficiency virus 1 reverse transcriptase, HIV-1 reverse transcriptase
- 同
- HIV-1逆転写酵素
- 関
- ヒト免疫不全症ウイルス1型
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- 英
- HIV-1 reverse transcriptase、human immunodeficiency virus type 1 reverse transcriptase
- 関
- ヒト免疫不全症ウイルス1型逆転写酵素
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- 関
- adversely、backward、converse、conversely、inverse、inversely、opposite、oppositely、retro、reversal
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- 関
- DNA-dependent RNA polymerase、DNA-directed RNA polymerase、RNA polymerase
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human immunodeficiency virus HIVウイルス ヒト免疫不全ウイルス
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