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- the 6th letter of the Roman alphabet (同)f
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出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/08/14 19:58:03」(JST)
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English Journal
- Biocompatibility of functionalized designer self-assembling nanofiber scaffolds containing FRM motif for neural stem cells.
- Zou Z1, Liu T, Li J, Li P, Ding Q, Peng G, Zheng Q, Zeng X, Wu Y, Guo X.Author information 1Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.AbstractPeptide self-assembling scaffolds have been widely used in tissue engineering. Much work has been focused on modifying the self-assembling scaffolds with functional motifs for desired biological activities. We report here the development of a biological material designed specifically for neural tissue engineering (NTE). Using RADA-16 (AcN-RADARADARADARADA-CONH2) as a base scaffold, we synthesized a 31 amino acid peptide RADA-FRM (AcN-RADARADARADARADAGGSIDRVEPYSSTAQ-CONH2) containing the neural cell adhesion molecule (NCAM)-derived mimetic peptide FRM (SIDRVEPYSSTAQ), which could undergo self-assembly into a nanofiber scaffold. We tested the characterization of the nanofiber scaffold using atomic force microscopy (AFM) and accessed the rheological properties of FRM-containing nanofiber scaffold (FRM-NS). Then we examined its biocompatibility on neural stem cells (NSCs) from neonatal rats. Regrettably, we found that FRM-NS had no effect on differentiation of NSCs. However, we tested that FRM-NS was noncytotoxic. Furthermore, compared to pure RADA-16 scaffold, we found that the designer self-assembling peptide scaffold containing FRM motif could significantly promote NSCs proliferation and stimulate NSCs migration into the three-dimensional scaffold. Our results indicate that the novel designer peptide scaffold containing FRM had excellent biocompatibility with NSCs and may be useful for central nervous tissue repair. © 2013 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 102A: 1286-1293, 2014.
- Journal of biomedical materials research. Part A.J Biomed Mater Res A.2014 May;102(5):1286-93. doi: 10.1002/jbm.a.34804. Epub 2013 Jun 4.
- Peptide self-assembling scaffolds have been widely used in tissue engineering. Much work has been focused on modifying the self-assembling scaffolds with functional motifs for desired biological activities. We report here the development of a biological material designed specifically for neural tiss
- PMID 23703883
- Causal inference for Mann-Whitney-Wilcoxon rank sum and other nonparametric statistics.
- Wu P1, Han Y, Chen T, Tu XM.Author information 1Department of Biostatistics and Computational Biology, University of Rochester, Rochester, NY 14623, U.S.A.AbstractThe nonparametric Mann-Whitney-Wilcoxon (MWW) rank sum test is widely used to test treatment effect by comparing the outcome distributions between two groups, especially when there are outliers in the data. However, such statistics generally yield invalid conclusions when applied to nonrandomized studies, particularly those in epidemiologic research. Although one may control for selection bias by using available approaches of covariates adjustment such as matching, regression analysis, propensity score matching, and marginal structural models, such analyses yield results that are not only subjective based on how the outliers are handled but also often difficult to interpret. A popular alternative is a conditional permutation test based on randomization inference [Rosenbaum PR. Covariance adjustment in randomized experiments and observational studies. Statistical Science 2002; 17(3):286-327]. Because it requires strong and implausible assumptions that may not be met in most applications, this approach has limited applications in practice. In this paper, we address this gap in the literature by extending MWW and other nonparametric statistics to provide causal inference for nonrandomized study data by integrating the potential outcome paradigm with the functional response models (FRM). FRM is uniquely positioned to model dynamic relationships between subjects, rather than attributes of a single subject as in most regression models, such as the MWW test within our context. The proposed approach is illustrated with data from both real and simulated studies.
- Statistics in medicine.Stat Med.2014 Apr 15;33(8):1261-71. doi: 10.1002/sim.6026. Epub 2013 Oct 16.
- The nonparametric Mann-Whitney-Wilcoxon (MWW) rank sum test is widely used to test treatment effect by comparing the outcome distributions between two groups, especially when there are outliers in the data. However, such statistics generally yield invalid conclusions when applied to nonrandomized st
- PMID 24132928
- Toll-interacting protein modulates colitis susceptibility in mice.
- Maillard MH1, Bega H, Uhlig HH, Barnich N, Grandjean T, Chamaillard M, Michetti P, Velin D.Author information 1*Service of Gastroenterology and Hepatology, Department of Medicine, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland; †Translational Gastroenterology Unit, Division of Experimental Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom; ‡M2iSH, UMR1071 Inserm, Université d'Auvergne, USC-INRA 2018, Clermont-Ferrand, France; §Institut Universitaire de Technologie en Génie Biologique, Aubière, France; ‖Univ Lille Nord de France, Lille, France; ¶Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France; **Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8204, Lille, France; ††Institut National de la Santé et de la Recherche Médicale, U1019, Team 7, Equipe FRM, Lille, France; and ‡‡La Source-Beaulieu, Lausanne, Switzerland.AbstractBACKGROUND: The intestinal epithelium accommodates with a myriad of commensals to maintain immunological homeostasis, but the underlying mechanisms regulating epithelial responsiveness to flora-derived signals remain poorly understood. Herein, we sought to determine the role of the Toll/interleukin (IL)-1 receptor regulator Toll-interacting protein (Tollip) in intestinal homeostasis.
- Inflammatory bowel diseases.Inflamm Bowel Dis.2014 Apr;20(4):660-70. doi: 10.1097/MIB.0000000000000006.
- BACKGROUND: The intestinal epithelium accommodates with a myriad of commensals to maintain immunological homeostasis, but the underlying mechanisms regulating epithelial responsiveness to flora-derived signals remain poorly understood. Herein, we sought to determine the role of the Toll/interleukin
- PMID 24572204
Japanese Journal
- FC店支援の現場 住宅販売には不慣れなFC店でも経験あるFRMが知識とスキルを伝授 (フランチャイズ本部徹底解剖シリーズ(第17回)ユニバーサルホーム)
- Franja 85, 62-64, 2015-03
- NAID 40020360604
- PM₂.₅質量濃度測定データを用いた自動測定機による時間値の測定精度評価の試み
- 板野 泰之,日置 正,菅田 誠治 [他]
- 大気環境学会誌 = Journal of Japan Society for Atmospheric Environment 50(2), 123-129, 2015
- NAID 40020389241
- The influences of position and forced respiratory maneuvers on spinal stability muscles
- , ,
- Journal of Physical Therapy Science 27(2), 491-493, 2015
- … [Subjects and Methods] Thirty-three healthy subjects performed quiet breathing and four different forced respiratory maneuvers (FRM); … %MVIC changes of muscle activities induced by FRM were independent of position with a few exceptions. … [Conclusion] The increased respiratory demands of FRM induced greater activation of spinal stability muscles than QB. …
- NAID 130004835133
Related Links
- 不動産を通じて｢未来価値」を創造する企業FRM.
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★リンクテーブル★
| リンク元 | 「ネオマイシン」 |
| 関連記事 | 「FR」「F」 |
「ネオマイシン」
- 英
- neomycin NM
- 同
- 硫酸フラジオマイシン fradiomycin sulfate フラジオマイシン fradiomycin fradiomycinum FRM、フラマイセチン framycetin
- 商
- フラジオ、(軟膏)ソフラチュール、(軟膏)(フラジオマイシン・フルオシノロン)フルコート、デルモラン、(軟膏)(フラジオマイシン・クロラムフェニコール)クロマイ、ハイセチン、(軟膏)(フラジオマイシン・メチルプレドニゾロン)ネオメドロール、(軟膏)(フラジオマイシン・バシトラシン)バラマイシン、(軟膏)(フラジオマイシン・ヒドロコルチゾン)プロクトセディル、(軟膏)(フラジオマイシン・ヒドロコルチゾン・ジフェンヒドラミン)レスタミンコーチゾン、(軟膏)(フラジオマイシン・ベタメタゾン)ベトネベート、(含嗽)デンターグル、(点眼・点鼻)(ベタメタゾン・フラジオマイシン)ベルベゾロン、リンデロン、(噴霧液)(プレドニゾロン・フラジオマイシン)エアゾリン、(噴霧液)(コリスチン・フラジオマイシン)コリマイフォーム、(その他)フランセチン、ヘモレックス
- 抗菌薬
- 蛋白合成阻害
- アミノグリコシド系抗菌薬