- 関
- See DNA-dependent protein kinase
WordNet
- the 4th letter of the Roman alphabet (同)d
- the 16th letter of the Roman alphabet (同)p
- a river in western Thailand; a major tributary of the Chao Phraya (同)Ping River
PrepTutorEJDIC
- deuteriumの化学記号
- parking
- phosphorusの化学記号
- deoxyribonucleic acidディオキシリボ核酸
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. スケドスポリウム感染の診断および治療 diagnosis and treatment of scedosporium infection
- 2. トラコーマの概要 overview of trachoma
- 3. 瘢痕性眼類天疱瘡 ocular cicatricial pemphigoid
- 4. 不育症の定義および病因 definition and etiology of recurrent pregnancy loss
- 5. DNAによる親子鑑定 parentage testing using dna
English Journal
- Emerging roles of DNA-PK besides DNA repair.
- Kong X, Shen Y, Jiang N, Fei X, Mi J.SourceRenji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
- Cellular signalling.Cell Signal.2011 Aug;23(8):1273-80. Epub 2011 Apr 15.
- The DNA-dependent protein kinase (DNA-PK) is a DNA-activated serine/threonine protein kinase, and abundantly expressed in almost all mammalian cells. The roles of DNA-PK in DNA-damage repair pathways, including non-homologous end-joining (NHEJ) repair and homologous recombinant (HR) repair, have bee
- PMID 21514376
- Suppression of DNA-PKcs and Ku80 individually and in combination: Different effects of radiobiology in HeLa cells.
- Zhuang L, Cao Y, Xiong H, Gao Q, Cao Z, Liu F, Qiu H, Yu S, Huang X.SourceCancer Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan Hubei 430030, P.R. China.
- International journal of oncology.Int J Oncol.2011 Aug;39(2):443-51. doi: 10.3892/ijo.2011.1041. Epub 2011 May 13.
- DNA-dependent protein kinase (DNA-PK), including Ku80, Ku70 and DNA-PK catalytic subunit (DNA-PKcs), is the key protein in non-homologous end-joining (NHEJ) after DNA double-strand breaks (DSBs) appear. In this study, small hairpin interfering RNAs (siRNAs) targeting Ku80 and DNA- PKcs were used bot
- PMID 21573502
Japanese Journal
- Involvement of DNA-PK and ATM in Radiation- and Heat-induced DNA Damage Recognition and Apoptotic Cell Death
- TOMITA Masanori
- Journal of radiation research 51(5), 493-501, 2010-09-16
- … Exposure to ionizing radiation and hyperthermia results in important biological consequences, e.g. cell death, chromosomal aberrations, mutations, and DNA strand breaks. … There is good evidence that the nucleus, specifically cellular DNA, is the principal target for radiation-induced cell lethality. … DNA double-strand breaks (DSBs) are considered to be the most serious type of DNA damage induced by ionizing radiation. …
- NAID 10026644057
- ATM is the Predominant Kinase Involved in the Phosphorylation of Histone H2AX after Heating
- TAKAHASHI Akihisa,MORI Eiichiro,SU Xiaoming,NAKAGAWA Yosuke,OKAMOTO Noritomo,UEMURA Hirokazu,KONDO Natsuko,NODA Taichi,TOKI Atsushi,EJIMA Yosuke,CHEN David J.,OHNISHI Ken,OHNISHI Takeo
- Journal of radiation research 51(4), 417-422, 2010-07-16
- … The cell lines used were DNA-PKcs knockout cells, ATM knockout cells, and their parental cell lines. … To elucidate mechanisms of induction of phosphorylation of H2AX after heating, ATM/ATR inhibitor (CGK733) and DNA-PK inhibitor (NU7026) were used. … The thermal dose-response curve for the fluorescence intensity of γH2AX appearance in DNA-PKcs–/– … cells during the heating period was similar to that observed in DNA-PKcs+/+ cells. …
- NAID 10026563899
Related Links
- DNA-PKはDNA二重鎖切断修復において中心的な役割を担うタンパク質リン酸化酵素である が、生体内での基質についてはほとんど明らかになっていない。一方、Protein kinase B (PKB/Akt)は細胞生存において重要な役割を担う。今回、Bozulicらは、DNA二重鎖切断 ...
Related Pictures
★リンクテーブル★
| リンク元 | 「カスパーゼ」 |
| 関連記事 | 「D」「DNA」「P」「PK」 |
「カスパーゼ」
- 英
- caspase
- 同
- ICEファミリープロテアーゼ ICE family protease
ヒトICEプロテアーゼスーパーファミリー
| Family | Caspase | Other Name | Recognition | Target (Truncation site) |
| caspase-1 | caspase-1 | ICE | WEHD | pro IL-1β (FEAD/G, YVHD/A), procaspase-3, procaspase-4 |
| caspase-4 | ICErel-II, TX, ICH-2 | |||
| caspase-5 | ICErel-III, TY | |||
| caspase-2 | caspase-2 | ICH-1 | DEHD | PARP (DEVD/G) |
| caspase-9 | ICE-LAP6, Mch6 | LEHD | PARP, procaspase-3 | |
| caspase-3 | caspase-3 | CPP32, Yama | DEVD | PARP, SREBP (DEPD/S), U1snRNP (DGPD/G), lamin B, D4-GDI (DELD/S), DNA-PK (DEVD/N), DFF (DETD/S, DAVD/T), actin (ELPD/G) ?, PKCδ (DMQD/N) ?]] |
| caspase-7 | Mch3, ICE-LAP3, CMH-1 | DEVD | PARP, procaspase-6 | |
| caspase-6 | Mch2 | VEHD | lamin A (VEID/N)]] | |
| caspase-8 | FLICE, MACH, Mch5 | LETD | procaspase-3, Bid | |
| caspase-10 | Mch4 | LEXD | ||
| caspase-11 | Ich3 |
「D」
- アスパラギン酸
- ジヒドロウリジン
- 遠位の distal,
- うつ病 depression
- 下行結腸 descending colon(大腸内視鏡検査の結果を記載するときに用いる)
「DNA」
- 英
- deoxyribonucleic acid
- 同
- デオキシリボ核酸
- 関
- リボ核酸 RNA
「P」