心臓再同期療法ペースメーカー、両室ペースメーカー

WordNet

the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system
the 16th letter of the Roman alphabet (同)p
a river in western Thailand; a major tributary of the Chao Phraya (同)Ping River

PrepTutorEJDIC

carbonの化学記号
parking
phosphorusの化学記号
palladiumの化学記号

UpToDate Contents

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1. 心不全における心臓再同期療法：適応 cardiac resynchronization therapy in heart failure indications
2. 心臓再同期療法の利益の理論的根拠および機序 rationale for and mechanisms of benefit of cardiac resynchronization therapy
3. 心不全における心臓再同期療法：植込みおよびその他の考慮事項 cardiac resynchronization therapy in heart failure implantation and other considerations
4. 心房細動における心臓再同期療法 cardiac resynchronization therapy in atrial fibrillation
5. 心不全および心筋症における心臓突然死の一次予防 primary prevention of sudden cardiac death in heart failure and cardiomyopathy

English Journal

Relationship of serum levels of VEGF and TGF-β1 with radiosensitivity of elderly patients with unresectable non-small cell lung cancer.

Fu ZZ1, Gu T, Fu BH, Hua HX, Yang S, Zhang YQ, Gao LM, Li P.Author information 1Department of Oncology, The First Hospital of Qinhuangdao, Wenhua Road No.2, Haigang District, Qinhuangdao, 066000, People's Republic of China, qhdfh_gt@126.com.AbstractThis study aimed to evaluate the relationship of serum levels of vascular endothelial growth factor (VEGF) and transforming growth factor-β1 (TGF-β1) with radiosensitivity of elderly patients with unresectable non-small cell lung cancer (NSCLC) receiving three-dimensional conformal radiation therapy (3D-CRT). Fifty-eight elderly patients with unresectable NSCLC and 40 healthy controls were enrolled in this study. Serum levels of VEGF and TGF-β1 were detected by the enzyme-linked immunosorbent assay (ELISA) method before and after 3D-CRT. Clinical performances of serum VEGF and TGF-β1 levels in predicting radiosensitivity of NSCLC patients with 3D-CRT were evaluated. Serum VEGF and TGF-β1 levels of NSCLC patients were higher than those of health controls (all p < 0.05). After 3D-CRT treatment, 41 patients achieved effective clinical response (complete response (CR) + partial response (PR)) and 17 patients were ineffective clinical response (stable disease (SD) + progressive disease (PD)). There was no significant difference in the VEGF and TGF-β1 levels between the effective and ineffective groups before 3D-CRT (all p > 0.05). Serum levels of VEGF and TGF-β1 after 3D-CRT in the effective group were lower compared with the levels before 3D-CRT treatment (p < 0.001 and 0.027, respectively). However, no significant differences in serum VEGF and TGF-β1 levels between before and after 3D-CRT in the ineffective group were observed (p = 0.196 and 0.517, respectively). We observed significant differences in serum VEGF and TGF-β1 levels between the effective and ineffective groups after 3D-CRT (p < 0.001 and 0.013, respectively). Sensitivity and specificity of VEGF combined with TGF-β1 in predicting radiosensitivity of NSCLC patients with 3D-CRT were 87.8 and 94.1 %, respectively. In conclusion, our results indicate that serum VEGF and TGF-β1 levels may accurately predict radiosensitivity of elderly patients with unresectable NSCLC receiving 3D-CRT.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.Tumour Biol.2014 Feb 21. [Epub ahead of print]
This study aimed to evaluate the relationship of serum levels of vascular endothelial growth factor (VEGF) and transforming growth factor-β1 (TGF-β1) with radiosensitivity of elderly patients with unresectable non-small cell lung cancer (NSCLC) receiving three-dimensional conformal radiation thera
PMID 24557540

[Influence of the cardiac resynchronisation therapy on the coronary blood flow in patients with non-ischaemic dilated cardiomyopathy.]

Kaźmierczak J1, Peregud-Pogorzelska M, Gorący J, Wojtarowicz A, Kiedrowicz R, Kornacewicz-Jach Z.Author information 1Klinika Kardiologii Pomorski Uniwersytet Medyczny Szczecin, Polska. jar.kazmierczak@o2.pl.AbstractBACKGROUND: Cardiac resynchronisation therapy (CRT) has beneficial effects on cardiac function, exercise tolerance, symptoms and prognosis. Coronary blood flow impairment has been observed in patients with non-ischemic dilated cardiomyopathy (DCM) despite angiographically normal coronary arteries. No data are available on the relation of coronary blood flow and coronary flow reserve (CFR) measured by intracoronary Doppler in different coronary arteries in patients with DCM and LBBB before and during treatment with CRT.
Kardiologia polska.Kardiol Pol.2014 Feb 14. doi: 10.5603/KP.a2014.0019. [Epub ahead of print]
BACKGROUND: Cardiac resynchronisation therapy (CRT) has beneficial effects on cardiac function, exercise tolerance, symptoms and prognosis. Coronary blood flow impairment has been observed in patients with non-ischemic dilated cardiomyopathy (DCM) despite angiographically normal coronary arteries. N
PMID 24526554

A comparison of left ventricular endocardial, multisite, and multipolar epicardial cardiac resynchronization: an acute haemodynamic and electroanatomical study.

Shetty AK1, Sohal M, Chen Z, Ginks MR, Bostock J, Amraoui S, Ryu K, Rosenberg SP, Niederer SA, Gill J, Carr-White G, Razavi R, Rinaldi CA.Author information 1Department of Imaging Sciences, Rayne Institute, Kings College London, London SE1 7EH, UK.AbstractAIMS: Alternative forms of cardiac resynchronization therapy (CRT), including biventricular endocardial (BV-Endo) and multisite epicardial pacing (MSP), have been developed to improve response. It is unclear which form of stimulation is optimal. We aimed to compare the acute haemodynamic response (AHR) and electrophysiological effects of BV-Endo with MSP via two separate coronary sinus (CS) leads or a single-quadripolar CS lead.METHODS AND RESULTS: Fifteen patients with a previously implanted CRT system received a second temporary CS lead and left ventricular (LV) endocardial catheter. A pressure wire and non-contact mapping array were placed into the LV cavity to measure LVdP/dtmax and perform electroanatomical mapping. Conventional CRT, BV-Endo, and MSP were then performed (MSP-1 via two epicardial leads and MSP-2 via a single-quadripolar lead). The best overall AHR was found using BV-Endo pacing with a 19.6 ± 13.6% increase in AHR at the optimal endocardial site over baseline (P < 0.001). There was an increase in LVdP/dtmax with MSP-1 and MSP-2 compared with conventional CRT, but this was not statistically significant. Biventricular endocardial pacing from the optimal site was significantly superior to conventional CRT (P = 0.039). The AHR achieved when BV-Endo pacing was highly site specific. Within individuals, the best pacing modality varied and was affected by the underlying substrate. Left ventricular activation times did not predict the optimal haemodynamic configuration.CONCLUSION: Biventricular endocardial pacing and not MSP was superior to conventional CRT, but was highly site specific. Within individuals, however, different methods of stimulation are optimal and may need to be tailored to the underlying substrate.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.Europace.2014 Feb 12. [Epub ahead of print]
AIMS: Alternative forms of cardiac resynchronization therapy (CRT), including biventricular endocardial (BV-Endo) and multisite epicardial pacing (MSP), have been developed to improve response. It is unclear which form of stimulation is optimal. We aimed to compare the acute haemodynamic response (A
PMID 24525553

Japanese Journal

CRT-Dの植込み手技 (Up-to-Date Art&Technique CRT-P/Dの手技)

菅原養厚,三橋武司,百村伸一
Circulation up-to-date 8(5), 517-521, 2013-10
NAID 40019820695

適応 (Up-to-Date Art&Technique CRT-P/Dの手技)

三橋武司,百村伸一
Circulation up-to-date 8(5), 509-516, 2013-10
NAID 40019820690

原理 (Up-to-Date Art&Technique CRT-P/Dの手技)

三橋武司,百村伸一
Circulation up-to-date 8(5), 504-508, 2013-10
NAID 40019820678

Related Pictures

inlivenᵀᴹ crt p cardiac Cardiac Resynchronization (CRT-D) 追求した crt p syncra crt p 誕生 resynchronization therapy pacemaker crt p therapy pacemaker crt p a a resize print Therapy Pacemaker (CRT-P manchon-110-texture-crt-p-10-outilp

★リンクテーブル★

リンク元	「心臓再同期療法ペースメーカー」
関連記事	「C」「CRT」「CR」「P」「p」

「心臓再同期療法ペースメーカー」

　　[★]

英: CRT-P
関: 除細動器付き心臓再同期療法ペースメーカー, CRT-D

適応

慢性心不全治療ガイドライン

Class I

最適の薬物治療でもNYHA III度または一時的にIV度の慢性心不全を呈し，LVEF 35％以下，QRS幅120 msec 以上で，洞調律を有する場合（エビデンスレベルA）

Class IIa

最適の薬物治療でもNYHAClass IIIまたは一時的にClass IVの慢性心不全を呈し，LVEF 35 ％以下，QRS幅120 msec以上で，心房細動を有する場合（エビデンスレベルB）
最適の薬物治療でもNYHA III度または一時的にIV度の慢性心不全を呈し，LVEF 35％以下で，ペースメーカが植込まれ，または予定され，高頻度に心室ペーシングに依存する場合（エビデンスレベル

C）