WordNet
- (genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity; "genes were formerly called factors" (同)cistron, factor
- informal term for information; "give me the gen on your new line of computers"
PrepTutorEJDIC
- 遺伝子
UpToDate Contents
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- 1. 嚢胞性線維症：遺伝学と病因 cystic fibrosis genetics and pathogenesis
- 2. 嚢胞性線維症：臨床症状および診断 cystic fibrosis clinical manifestations and diagnosis
- 3. 成人における慢性膵炎の病因および発症機序 etiology and pathogenesis of chronic pancreatitis in adults
- 4. 嚢胞性線維症：出生前の遺伝学的スクリーニング cystic fibrosis prenatal genetic screening
- 5. 男性不妊症の評価 evaluation of male infertility
English Journal
- Isolated liver disease in a patient with a CFTR genotype F508del/12TG-5T and 470MV: A new face of an old disease.
- Praticò AD1, Praticò ER1, Rotolo N1, Salafia S1, Franzonello C1, Leonardi S1.
- Annals of hepatology.Ann Hepatol.2015 Nov-Dec;14(6):933-6. doi: 10.5604/16652681.1171787.
- Today the knowledge of genotype-phenotype correlation in cystic fibrosis is enriched by the growing discoveries of new mutations of the CFTR gene. Although the combination of two severe mutations usually leads to the classic disease (pulmonary and pancreatic insufficiency, sterility, nasal polyposis
- PMID 26436368
- Novel mutations and polymorphisms in the CFTR gene associated with three subtypes of congenital absence of vas deferens.
- Yang X1, Sun Q2, Yuan P3, Liang H4, Wu X1, Lai L4, Zhang Y5.
- Fertility and sterility.Fertil Steril.2015 Nov;104(5):1268-1275.e2. doi: 10.1016/j.fertnstert.2015.07.1143. Epub 2015 Aug 12.
- OBJECTIVE: To study the new genotypes in congenital absence of vas deferens (CAVD) and the correlation with different phenotypes, and to investigate the pathogenesis of the disease based on bioinformatics analysis.DESIGN: Case-control study.SETTING: University-affiliated tertiary teaching hospital.
- PMID 26277102
- Transcriptome meta-analysis reveals common differential and global gene expression profiles in cystic fibrosis and other respiratory disorders and identifies CFTR regulators.
- Clarke LA1, Botelho HM1, Sousa L2, Falcao AO3, Amaral MD1.
- Genomics.Genomics.2015 Nov;106(5):268-77. doi: 10.1016/j.ygeno.2015.07.005. Epub 2015 Jul 29.
- A meta-analysis of 13 independent microarray data sets was performed and gene expression profiles from cystic fibrosis (CF), similar disorders (COPD: chronic obstructive pulmonary disease, IPF: idiopathic pulmonary fibrosis, asthma), environmental conditions (smoking, epithelial injury), related cel
- PMID 26225835
Japanese Journal
- のう胞性線維症におけるトランスレーショナルリサーチ
- 吉村 邦彦,江島 美保
- 呼吸器内科 21(6), 565-574, 2012-06
- NAID 40019361476
- Synergism Between Interleukin (IL)-17 and Toll-like Receptor 2 and 4 Signals to Induce IL-8 Expression in Cystic Fibrosis Airway Epithelial Cells
- MIZUNOE Shota,SHUTO Tsuyoshi,SUZUKI Shingo,MATSUMOTO Chizuru,WATANABE Kenji,UENO SHUTO Keiko,SUICO Mary Ann,ONUKI Kouhei,GRUENERT Dieter C.,KAI Hirofumi
- Journal of pharmacological sciences 118(4), 512-520, 2012-04-20
- … Cystic fibrosis (CF) is the most common lethal inherited disorder and is caused by mutations in the gene encoding the CF transmembrane regulator (CFTR). …
- NAID 10030572169
- Distal intestinal obstruction syndromeを認めた嚢胞性線維症の1例
- 向井 基,松藤 凡,加治 建,池江 隆正,川野 孝文,松久保 眞,右田 美里
- 日本小児外科学会雑誌 47(5), 848-851, 2011-08-20
- … transmembrane conductance regulator(CFTR)遺伝子のdeletion解析で,エクソン16,17a,17bにまたがる完全欠失のホモ接合が判明し,嚢胞性線維症の診断が確定した.イレウス症状は嚢胞性線維症の一症状であるdistal intestinal obstruction syndromeに該当すると思われた.嚢胞性線維症は本邦において現在考えられているより罹患率の高い疾患である可能性があり,本症が疑われる場合汗電解質測定やCFTR遺伝子解析を考慮する必要 …
- NAID 110008711758
Related Links
- The CFTR gene provides instructions for making a protein called the cystic fibrosis transmembrane conductance regulator. This protein functions as a channel across the membrane of cells that produce mucus, sweat ...
- Complete information for CFTR gene (protein-coding), cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7), including: function, proteins, disorders, pathways, orthologs, and expression.
Related Pictures
★リンクテーブル★
| 関連記事 | 「CF」「CFTR」「CFT」 |
「CF」
- 冠状動脈血流 冠動脈血流 coronary flow
- 補体結合反応試験 complement fixation test
- 嚢胞性線維症 cystic fibrosis
- ロイコボリン leucovorin calcium
- 登上線維 climbing fiber climbing fibre
- 楔状束 cuneate fasciculus
- 冠血流 coronary flow
- 大腸ファイバースコープ colon fiberscope、大腸内視鏡、下部消化管内視鏡
「CFTR」
[★] 嚢胞性線維症膜貫通調節蛋白質 cystic fibrosis transmembrane regulator