WordNet

the 3rd letter of the Roman alphabet (同)c
(music) the keynote of the scale of C major
a general-purpose programing language closely associated with the UNIX operating system

PrepTutorEJDIC

carbonの化学記号

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1. 補体経路 complement pathways
2. リウマチ性血管炎の疫学および病因 epidemiology and pathogenesis of rheumatoid vasculitis
3. 自然免疫系の概要 an overview of the innate immune system
4. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
5. 補体系の制御因子および受容体 regulators and receptors of the complement system

English Journal

Human Tamm-Horsfall protein, a renal specific protein, serves as a cofactor in complement 3b degradation.

Rhodes DCJ1.
PloS one.PLoS One.2017 Jul 24;12(7):e0181857. doi: 10.1371/journal.pone.0181857. eCollection 2017.
PMID 28742158

Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration.

Yaspan BL1, Williams DF2, Holz FG3, Regillo CD4, Li Z1, Dressen A1, van Lookeren Campagne M1, Le KN1, Graham RR1, Beres T1, Bhangale TR1, Honigberg LA1, Smith A1, Henry EC1, Ho C1, Strauss EC5; MAHALO Study Investigators.
Science translational medicine.Sci Transl Med.2017 Jun 21;9(395). pii: eaaf1443. doi: 10.1126/scitranslmed.aaf1443.
PMID 28637922

An extremely rare splice site mutation in the gene encoding complement factor I in a patient with atypical hemolytic uremic syndrome.

Ipe TS1, Lim J2, Reyes MA3, Ero M2, Leveque C1, Lewis B2, Kain J2.
Journal of clinical apheresis.J Clin Apher.2017 Apr 28. doi: 10.1002/jca.21549. [Epub ahead of print]
PMID 28455885

Related Links

C3b inactivator deficiency with immune complex manifestations.

We report a complete C3b inactivator deficiency in a 28-year-old patient referred for bronchiectasis and recurrent pneumonia. In addition to these recurrent infections, previously described with this deficiency, he also had several ...

Title ヒト factor I (C3b inactivator) の遺伝的多型 URL

Twinkle:Tokyo Women's Medical University - Information & Knowledge Database. http://ir.twmu.ac.jp/dspace/ Title ヒト factor I (C3b inactivator) の遺伝的多型 Author(s) 中村, 茂基 Journal 東京女子医科大学雑誌, 57(8):970-971, 1987

★リンクテーブル★

リンク元	「I因子」「C3b不活性化因子」
拡張検索	「complement C3b inactivator protein」「C3b inactivator deficiency」
関連記事	「C3b」「C3」「C」「inactivator」

「I因子」

　　[★]

英: factor I
同: C3b不活性化因子 C3b inactivator C3b INA, I

「C3b不活性化因子」

　　[★]

英: C3b inactivator, C3b INA
関: I因子

「complement C3b inactivator protein」

　　[★]

補体C3b不活性化因子、補体C3bインアクチベータ

「C3b inactivator deficiency」

　　[★] C3b不活性化因子欠損症

「C3b」

　　[★]

関: 補体

古典的経路：C3からC4b2aのもつC3 convatase活性により生成し、C4b2a3bはC5 convertase活性を持つ (2008前期免疫学プリント 68)
別経路：C3からC3bBbPのもつC3 convertase活性により生成し、n(C3bBb)はC5 convertase活性を持つ (2008前期免疫学プリント 68)
別経路では細菌の表面でC3bが安定的に存在→オプソニン作用を有する