- 関
- LD50、lethal dose 50、median lethal dose
WordNet
- travel or traverse (a distance); "This car does 150 miles per hour"; "We did 6 miles on our hike every day"
- the syllable naming the first (tonic) note of any major scale in solmization (同)doh, ut
- proceed or get along; "How is she doing in her new job?"; "How are you making out in graduate school?"; "Hes come a long way" (同)fare, make_out, come, get along
- create or design, often in a certain way; "Do my room in blue"; "I did this piece in wood to express my love for the forest" (同)make
- carry on or function; "We could do with a little more help around here" (同)manage
- get (something) done; "I did my job" (同)perform
- treat with an agent; add (an agent) to; "The ray dosed the paint"
- the quantity of an active agent (substance or radiation) taken in or absorbed at any one time (同)dosage
- a measured portion of medicine taken at any one time (同)dosage
- treated with some kind of application; "a mustache dosed with bear grease"
PrepTutorEJDIC
- 《疑問文・否定文を作る》 / 《否定命令文を作る》 / 《助動詞とbe動詞のどちらも含まない文に用いて付加疑問を作る》 / 《強意語として》 / 《文》《助動詞とbe動詞のどちらも含まない文に用いて倒置文を作る》 / 《あいづちを打つ場合に》 / 《先行する動詞またはそれを含む述部の代用》 / 《so,nor,neitherで始まる簡略文で》 / …‘を'『する』,行う,果たす / 《通例have done,時にbe doneの形で》…‘を'『終える』,済ませる / …‘を'作る,作り出す / …‘を'『処理する』,整える,片付ける / 〈学課〉‘を'『勉強する』,専攻する / 〈利益・害など〉‘を'与える,もたらす / 〈人〉‘に'『役立つ』,用が足りる(serve) / …の速度で進む,距離を行く / …‘を'見物する / 〈劇〉‘を'上演する;…‘の'役を演じる / …の役目(仕事)をする / 《おもに英》…‘を'だます,かつぐ / 《話》…をへとへとにさせる / 『する』;活動する / 《通例have done,時にbe doneの形で》(…を)『終える』,済ます《+『with』+『名』》 / 〈事が〉『運ぶ』;〈人が〉暮らしていく,健康である / 〈物が〉(…に)『間に合う』,十分である;〈人が〉(…に)役に立つ,向く《+『for』+『名』》 / 《複数形で》すべきこと / 〈C〉《おもに英》大宴会,大パーティー / 〈C〉《英話》詐欺,ぺてん
- ド(全音階の第1音)
- (おもに飲み薬1回分の)『服用量』 / (痛いこと・いやなことの)1回分,一定量 / (人などが受ける放射線の)線量 / 性病 / (…を)…‘に'投薬する,服用させる《+『名』+『with』+『名』》
- 死をもたらす,致死の;死をもたらす目的の
UpToDate Contents
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English Journal
- Diospyros perigrena bark extract induced apoptosis in filarial parasite Setaria cervi through generation of reactive oxygen species.
- Saini P1, Mukherjee N, Mukherjee S, Roy P, Gayen P, Kumar D, Pal BC, Sinha Babu SP.
- Pharmaceutical biology.Pharm Biol.2015 Jun;53(6):813-23. doi: 10.3109/13880209.2014.943244. Epub 2015 Feb 27.
- CONTEXT: Lymphatic filariasis is a major neglected tropical disease. Diospyros perigrena Gurke (Ebenaceae) was selected for antifilarial chemotherapy because of unavailability of proper medicine. In India, different parts of this plant were used for the treatment of diabetes, diarrhea, dysentery, ch
- PMID 25720973
- Improved bioassays using a local effect, such as muscle paralysis, as an endpoint.
- Cevc G1.
- Toxicon : official journal of the International Society on Toxinology.Toxicon.2015 Jun 1;99:89-94. doi: 10.1016/j.toxicon.2015.03.012. Epub 2015 Mar 21.
- Drug potency testing consumes many animals, botulinum neurotoxin (BoNT) testing being perhaps the most notorious example. To avoid 50% lethal dose determination, the so-called digital abduction score (DAS) and other BoNT induced local paralysis assays were developed. This paper reveals that a simple
- PMID 25804992
- The M949_1556 gene plays a role on the bacterial antigenicity and pathogenicity of Riemerella anatipestifer.
- Zou J1, Wang X1, Tian M1, Cao S1, Hou W1, Wang S1, Han X1, Ding C1, Yu S2.
- Veterinary microbiology.Vet Microbiol.2015 May 15;177(1-2):193-200. doi: 10.1016/j.vetmic.2015.03.003. Epub 2015 Mar 14.
- Riemerella anatipestifer is one of the most economically important pathogens of farm ducks worldwide. However, the molecular mechanisms regarding its antigenicity and pathogenicity are poorly understood. We previously constructed a library of random Tn4351 transposon mutants using R. anatipestifer s
- PMID 25804836
Japanese Journal
- Chick embryo chorioallantoic membrane (CAM): an alternative predictive model in acute toxicological studies for anti-cancer drugs
- , , ,
- Experimental Animals advpub(0), 2015
- … Suitable formulations for intravenous administration were determined before the average of median lethal dose (LD50) and median survival dose (SD50) in the CAM were measured and calculated for these drugs. … The resultant ideal LD50 values were correlated to those reported in the literature using Pearson's correlation test for both intravenous and intraperitoneal routes of injection in rodents. …
- NAID 130004921814
- Long-lasting Radioprotective Effects of a Combination of Pharmaceutical Drugs on the Survival of Mice Exposed to Lethal Ionizing Radiation
- Yamaguchi Masaru,Hirouchi Tokuhisa,Nakano Manabu [他]
- Radiation emergency medicine 3(1), 50
- NAID 40019977626
- Acute and Subacute Toxicity of the Extract of Aristolochiae Fructus and Honey-Fried Aristolochiae Fructus in Rodents
- , , [他], , , , , , , ,
- Biological and Pharmaceutical Bulletin 37(3), 387-393, 2014
- … The median lethal dose (LD50) of AF and HAF are 34.1±7.2 g/kg/d and 62.6±8.0 g/kg/d with a 95% average trustable probability (p=0.95), respectively. … The subacute results showed a dose-dependant relationship of the toxicity of AF and HAF. … Even in the high dose groups, only moderate toxicity was observed. …
- NAID 130003382130
Related Links
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- carry out、conduct、execute、make、perform、practice、undertake
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- deadly、fatal、fatally、lethally、mortal、vital
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- administration、medicate、prescription
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