… Further processing steps (post-translational modifications of the polypeptide chain) provide another layer of regulation: Cleavage of an upstream leader… Transcription occurs from the antisense DNA strand, in the 5' to 3' direction. Transcription requires that cellular machinery unfold the DNA to allow transcriptional regulators (transcription factors)…
…are 18 to 25 nucleotide non-protein encoding RNAs that play important roles in the regulation of posttranscriptional gene expression by incorporation into an RNA-induced silencing complex (RISC) that …
…has been identified in duodenal mucosa. It appears to function to evade iron-mediated post-transcriptional regulation in conditions of iron deficiency . The same isoform is expressed in erythroid cells and …
… investigators relied heavily upon in vitro progenitor assays to study the regulation of myelopoiesis. Both transcription factors and growth factors play an important… Metamyelocyte – Metamyelocytes are post-mitotic cells that are slightly smaller than myelocytes…
…interleukin 6 (IL-6), as illustrated in the examples below. There is no evidence for post-transcriptional regulation . Once TPO is produced, circulating TPO levels are regulated by the volume of the total …