- 英
- origin recognition complex、ORC
-ORC
- 関
- See Origin replication complex
UpToDate Contents
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- 1. 複合形質の遺伝の原則principles of complex trait genetics [show details]
… identify complex trait genes include linkage analyses, candidate gene testing, genome-wide association studies (GWAS), and next generation sequencing (NGS) or the entire exome or genome. Replication of findings… stability of a single protein by altering its three-dimensional structure. These mutations include point mutations (eg, changes in single nucleotides that alter the amino acid sequence), insertions, or deletions …
- 2. ミトコンドリアの構造、機能、および遺伝学mitochondrial structure function and genetics [show details]
… replication and segregation of mitochondrial chromosomes are not coupled to the cell cycle and can occur at any time. Mitochondrial DNA is found within DNA-protein complexes called nucleoids… and small subunits of the ribosome (comprised of 48 and 29 proteins, respectively) Translation initiation, elongation and release factors; Ribosomal protein assembly factors; mRNA polyadenylation factors; … a high mutation rate due to the lack of histones and to damage from oxygen radical species. Many point mutations as well as insertions, deletions, duplications and rearrangements of varying size and complexity…
- 3. 危篤状態の成人における鎮静鎮痛剤:選択、開始、維持、および離脱sedative analgesic medications in critically ill adults selection initiation maintenance and withdrawal [show details]
… zero to ten point scale on which ten represents the worst pain. Patients choose the number that best describes their pain. The multidimensional scales are more complex and take longer… outcomes. The management of agitation in critically ill adults is reviewed here, including the initiation, maintenance, and withdrawal of pharmacological sedation. Common sedative-analgesic medications …
- 4. HIV薬剤耐性検査結果の解釈についてinterpretation of hiv drug resistance testing [show details]
… Drug-resistant mutations can predate the initiation of a specific drug regimen or can develop when viral replication continues in the face of ongoing drug pressure.… drug-resistant variants, which can challenge an HIV clinician. While resistance mutation patterns can be complex, there are basic principles that underlie effective utilization of resistance data. This topic will … significant cross-resistance between those two agents . As a result, selection of one of these single point mutations (eg, Y181C or K103N) confers loss of activity to both drugs . K103N is selected by efavirenz …
- 5. 青年および成人におけるHIV感染の自然経過および臨床的特徴the natural history and clinical features of hiv infection in adults and adolescents [show details]
… Early symptomatic HIV infection (previously known as AIDS-related complex [ARC] or Class B).… recognizing early and acute HIV infection is that it allows early antiretroviral therapy (ART) initiation, which has several known and potential benefits. Symptomatic acute HIV infection is characterized … which is a period of rapid viral replication and infection of CD4 cells,…
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★リンクテーブル★
[★]
- 関
- origin recognition complex
- 関
- See Origin replication complex
[★]
- 関
- ORC
[★]
- 英
- initiation、start、onset、commencement、start、initiate、mount、institute、commence
- 関
- イニシエーション、イニシエート、オンセット、研究所、設立、着手、発症、発生、始める、惹起、起動、発病、始動、乗せる、高まる、スタート、マウント
-initiation
[★]
- 英
- complex、complexes、composite
- 関
- 合成物、錯体、多層、複合性、複合物、複雑、コンプレックス、複合
[★]
- 英
- origin of replication、replication origin、replicator
- 関
- 複製起点、自己複製装置、レプリケーター、複製オリジン
[★]
- 英
- body
- ラ
- corpus、corpora
- 関
- 肉体、身体、本体、コーパス、ボディー
[★]
- 英
- complex
- 関
- 合成物、錯体、複合体、複合物、複雑、コンプレックス