…binding to other nucleic acid chains. Other functions include protection from exonucleases, initiation of translation through ribosomal binding, and mRNA translocation from nucleus to cytoplasm. A long tail …
…large and small subunits of the ribosome (comprised of 48 and 29 proteins, respectively) Translation initiation, elongation and release factors; Ribosomal protein assembly factors; mRNA polyadenylation …
…disruption of the interactions between 3' UTR stabilizer sequences and their binding proteins. Translation initiation is the process by which the ribosome attaches itself near the 5' end of the mRNA molecule …
…autosomal recessive. Mutations in any of the five genes that encode subunits of the eukaryotic translation initiation factor eIF2B are the cause of CACH/VWM and its phenotypic variants . The eIF2B protein complex …
…and out-of-frame deletions involving exons 3 to 7, it is hypothesized that an alternative translation initiation site within exon 8 becomes activated . Some data suggest that genes other than dystrophin …