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1. 分子遺伝学の原理principles of molecular genetics [show details]
…binding to other nucleic acid chains. Other functions include protection from exonucleases, initiation of translation through ribosomal binding, and mRNA translocation from nucleus to cytoplasm. A long tail …
2. サラセミア症候群の分子遺伝学的特性molecular genetics of the thalassemia syndromes [show details]
…condition in which alpha chains are made in excess . Heme-regulated alpha-subunit of eukaryotic translational initiation factor 2 (eIF2alpha) kinase (HRI) prevents the accumulation of excess alpha- and beta-globin …
3. ミトコンドリアの構造、機能、および遺伝学mitochondrial structure function and genetics [show details]
… large and small subunits of the ribosome (comprised of 48 and 29 proteins, respectively) Translation initiation, elongation and release factors; Ribosomal protein assembly factors; mRNA polyadenylation …
4. 成人のHIV感染者の肺結核治療：治療開始後のフォローアップtreatment of pulmonary tuberculosis in hiv infected adults follow up after initiation of therapy [show details]
… clinical response depends in part on the timing relative to initiation of antituberculous therapy: Drug hypersensitivity (usually… but did not translate to a high proportion of patients with treatment failure .…
5. 消失性白質疾患（Vanishing white matter disease）vanishing white matter disease [show details]
… autosomal recessive. Mutations in any of the five genes that encode subunits of the eukaryotic translation initiation factor eIF2B are the cause of CACH/VWM and its phenotypic variants . The eIF2B protein complex …

English Journal

Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer.

Liu Q, Wang G, Li Q, Jiang W, Kim JS, Wang R, Zhu S, Wang X, Yan L, Yi Y, Zhang L, Meng Q, Li C, Zhao D, Qiao Y, Li Y, Gursel DB, Chinnaiyan AM, Chen K, Cao Q.
International journal of cancer. 2019 Jul;145(2)415-426.
Polycomb group proteins are important epigenetic regulators for cell proliferation and differentiation, organ development, as well as initiation and progression of lethal diseases, including cancer. Upregulated Polycomb group proteins, including Enhancer of zeste homolog 2 (EZH2), promote proliferat
PMID 30628724

The role of personalized atrial modeling in understanding atrial fibrillation mechanisms and improving treatment.

Aronis KN, Ali R, Trayanova NA.
International journal of cardiology. 2019 Jul;287()139-147.
Atrial fibrillation is the most common arrhythmia in humans and is associated with high morbidity, mortality and health-related expenses. Computational approaches have been increasingly utilized in atrial electrophysiology. In this review we summarize the recent advancements in atrial fibrillation m
PMID 30755334

RGS2 promotes the translation of stress-associated proteins ATF4 and CHOP via its eIF2B-inhibitory domain.

Wang CJ, Chidiac P.
Cellular signalling. 2019 Jul;59()163-170.
Regulator of G protein signaling 2 (RGS2) is upregulated by multiple forms of stress and can augment translational attenuation associated with the phosphorylation of the initiation factor eIF2, a hallmark of several stress-induced coping mechanisms. Under stress-induced translational inhibition, key
PMID 30826455

Japanese Journal

Coexistence of Mixed Connective Tissue Disease and Familial Mediterranean Fever in a Japanese Patient: A Case Report

Fujita Yuya,Koga Tomohiro,Endo Yushiro,Kawakami Atsushi,Migita Kiyoshi,Asano Tomoyuki,Sato Shuzo,Furuya Makiko Yashiro,Temmoku Jumpei,Matsuoka Naoki,Kobayashi Hiroko,Watanabe Hiroshi,Suzuki Eiji
Internal Medicine, 2019
… Four months after the initiation of colchicine treatment, she presented with MCTD-related pulmonary artery hypertension. …
NAID 130007633657

Geotechnical and Mineralogical Properties of Granite Regolith Related to Nucleation Mechanisms of Debris Flows in Tropical Areas

PICANÇO Jefferson,MESQUITA Maria José,MELO Leonardo L.
砂防学会英文誌 11(3), 54-62, 2019
… Debris flows are generated by landslide nucleation in steep initiation zones. … The understanding of these phenomena will help in defining the initiation zones of landslides with the potential to set off debris flows generated by translational landslides.</p> …
NAID 130007610663

Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle

Yokokawa Takumi,Kido Kohei,Suga Tadashi,Isaka Tadao,Hayashi Tatsuya,Fujita Satoshi
Physiological reports 6(20), 2018-10
… Two mitochondrial initiation factors (mtIF2 and mtIF3), three mitochondrial elongation factors (mtEFTu, mtEFTs, and mtEFG1), one mitochondrial release factor (mtRF1L), and two mitochondrial recycling factors (mtRRF1 and mtRRF2) are mitochondrial translation factors that coordinate each translational phase. …
NAID 120006534601