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1. 成人におけるうつ病治療としてのモノアミン酸化酵素阻害剤（MAOI）monoamine oxidase inhibitors maois for treating depressed adults [show details]
… Although some MAO activity is restored three to five days after discontinuing the medication, it is prudent to allow two weeks for full restoration of MAO activity after stopping tranylcypromine. Tranylcypromine …
2. 成人における抗うつ薬の切り替えswitching antidepressant medications in adults [show details]
…immediately or after a washout period. As an example, when patients are switched to a monoamine oxidase inhibitor (MAOI), the current antidepressant must first be tapered and then discontinued; the next …
3. パーキンソン病の初期薬物療法initial pharmacologic treatment of parkinson disease [show details]
… effects of MAO B inhibitors. Selegiline may cause confusion in older adults, more so than the other MAO B inhibitors, thereby limiting its use in patients with late-onset disease. Selegiline enhances the …
4. 成人における社会不安障害に対する薬物療法pharmacotherapy for social anxiety disorder in adults [show details]
…sufficiently tested: Moclobemide – Moclobemide, a reversible MAOI selective for inhibition of MAO-A, has shown, at best, mixed results in randomized controlled trials of SAD . Moclobemide is not marketed in …
5. 妊娠中の抗うつ薬の服用および催奇形性やそのほかの悪影響が生じる危険性について：選択的セロトニン再取り込み阻害薬以外の医薬品antenatal use of antidepressants and risks of teratogenicity and adverse pregnancy outcomes drugs other than selective serotonin reuptake inhibitors [show details]
…disorder or autism . Monoamine oxidase inhibitors include phenelzine, selegiline, and tranylcypromine. Animal studies have shown that exposure to monoamine oxidase inhibitors in pregnancy is associated …

Japanese Journal

法科学分野における毛髪中薬物の分析

志摩典明
日本毒性学会学術年会 47.1(0), S11-1, 2020
… 毛根（頭皮内に隠れている部位、約4 mm）の底部に在る毛母細胞から発生し、 1ヶ月に平均1.0～1.5 cmの速度で伸長する．一方、体内に摂取された薬物は、主に毛根から毛髪中へと取り込まれ、毛髪組織あるいは色素などと結合して定着し、毛髪の伸長と共に毛幹（頭皮外に露出した部位）側へと移行していくと考えられている．しかしながら、このような薬物の取り込みやその後の挙動に関しては、その詳細が十 …
NAID 130007898466