- 関
- wild type、wildtype、WT
WordNet
- write by means of a keyboard with types; "type the acceptance letter, please" (同)typewrite
- a small metal block bearing a raised character on one end; produces a printed character when inked and pressed on paper; "he dropped a case of type, so they made him pick them up"
- (biology) the taxonomic group whose characteristics are used to define the next higher taxon
- a subdivision of a particular kind of thing; "what type of sculpture do you prefer?"
- all of the tokens of the same symbol; "the word `element contains five different types of character"
- printed characters; "small type is hard to read"
- identify as belonging to a certain type; "Such people can practically be typed" (同)typecast
- marked by extreme lack of restraint or control; "wild talk"; "wild parties"
- a wild primitive state untouched by civilization; "he lived in the wild"; "they collected mushrooms in the wild" (同)natural state, state of nature
- in a natural state; not tamed or domesticated or cultivated; "wild geese"; "edible wild plants" (同)untamed
- deviating widely from an intended course; "a wild bullet"; "he threw a wild pitch"
- in a state of extreme emotion; "wild with anger"; "wild with grief"
- in a wild or undomesticated manner; "growing wild"; "roaming wild"
- a wild uncultivated plant (especially a wild apple or crabapple tree)
- an outrageous rampage usually involving sexual attacks by men on women
- writing done with a typewriter (同)typewriting
PrepTutorEJDIC
- 〈C〉(…の)『型』,タイプ,類型,種類(kind)《+of+名》 / 〈C〉(その種類の特質を最もよく表している)『典型』,手本,模範《+of+名》 / 〈U〉《集合的に》活字;〈C〉(1個の)活字 / 〈U〉(印刷された)字体,活字 / 〈C〉(貨幣・メダルなどの)模様,図柄 / 〈C〉血液型(blood group) / …‘を'タイプに打つ / (…として)…‘を'分類する《+名+as+名(doing)》 / …‘の'型を決める / タイプライターを打つ
- (植物・果実・はちみつなどが)『野生の』 / (鳥獣などが)『野生の』,飼い慣らされていない / (人・気性などが)『乱暴な』,無法な,手に負えない / 《おもに補語に用いて》『気違いじみた』,熱狂的な,ひどく興奮した / 《補語にのみ用いて》『熱望して』;夢中になって / (天候・海・時勢などが)『荒れた』,激しい / (人・種族などが)『未開の』 / (土地などが)『自然のままの』,荒涼とした / (計画などが)『とっぴな』,でたらめな / 的はずれの,見当違いの / 乱れた,だらしない / 《話》よい,愉快な / 『乱暴に』,やたらに;でたらめに / 荒野,荒れ地,大自然のままの状態
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2014/02/06 19:26:50」(JST)
[Wiki en表示]
Unlike culinary bananas, wild-type bananas have numerous large, hard seeds.
Wild type or wildtype (abbreviation wt) refers to the phenotype of the typical form of a species as it occurs in nature. Originally, the wild type was conceptualized as a product of the standard, "normal" allele at a locus, in contrast to that produced by a non-standard, "mutant" allele. It is now appreciated that most or all gene loci exist in a variety of allelic forms, which vary in frequency throughout the geographic range of a species, and that a uniform wild type does not exist. In general, however, the most prevalent allele[clarification needed] – e.g., the one with the highest gene frequency - is the one deemed as wild type.[1]
The concept of wild type is useful in some experimental organisms such as fruit flies Drosophila melanogaster, in which the standard phenotypes for features such as eye color or shape and wing form are known to be altered by particular gene mutations that produce distinctive phenotypes, such as "apricot" "bar eyes" or "vestigial wings". Wild-type alleles are indicated with a "+" superscript, for example B+ and vg+ for round eyes and full-size wings, respectively.
See also[edit]
- Genotype
- Phenotype
- Crop wild relative
References[edit]
- ^ Jones, Elizabeth; Hartl, Daniel L. (1998). Genetics: principles and analysis. Boston: Jones and Bartlett Publishers. ISBN 0-7637-0489-X.
External links[edit]
- "Absence of the wild-type allele" - Pediatrics
- "Genetically-spliced bacteria may benefit agriculture" - Sarasota Herald-Tribune
- "Reading of DNA allows creation of synthetic vaccines" - Star News
- "A Curious Clue in Cats" - Newsday
- "A Genetically Engineered Agriculture Revolution?" - The Telegraph
UpToDate Contents
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English Journal
- Combination of Rapamycin and Resveratrol for Treatment of Bladder Cancer.
- Alayev A1, Salamon RS1, Schwartz NS1, Berman AY1, Wiener SL1, Holz MK2,3.
- Journal of cellular physiology.J Cell Physiol.2017 Feb;232(2):436-446. doi: 10.1002/jcp.25443. Epub 2016 Jun 10.
- Loss of TSC1 function, a crucial negative regulator of mTOR signaling, is a common alteration in bladder cancer. Mutations in other members of the PI3K pathway, leading to mTOR activation, are also found in bladder cancer. This provides rationale for targeting mTOR for treatment of bladder cancer ch
- PMID 27225870
- Endocannabinoid dysregulation in cognitive and stress-related brain regions in the Nrg1 mouse model of schizophrenia.
- Clarke DJ1, Stuart J2, McGregor IS2, Arnold JC3.
- Progress in neuro-psychopharmacology & biological psychiatry.Prog Neuropsychopharmacol Biol Psychiatry.2017 Jan 4;72:9-15. doi: 10.1016/j.pnpbp.2016.08.006. Epub 2016 Aug 10.
- The endocannabinoid system is dysregulated in schizophrenia. Mice with heterozygous deletion of neuregulin 1 (Nrg1 HET mice) provide a well-characterised animal model of schizophrenia, and display enhanced sensitivity to stress and cannabinoids during adolescence. However, no study has yet determine
- PMID 27521758
- Inhibition of Allergic Response by Intranasal Selective NF-κB Decoy Oligodeoxynucleotides in a Murine Model of Allergic Rhinitis.
- Wee JH1, Zhang YL1, Rhee CS1, Kim DY2.
- Allergy, asthma & immunology research.Allergy Asthma Immunol Res.2017 Jan;9(1):61-69. doi: 10.4168/aair.2017.9.1.61.
- PURPOSE: It remains unknown whether local inhibition of Nuclear factor-kappa B (NF-κB) could have therapeutic value in the treatment of allergic rhinitis (AR). This study aimed to evaluate the effect of selective NF-κB inhibition using NF-κB decoy oligodeoxynucleotides (ODNs) for the local treatm
- PMID 27826963
Japanese Journal
- Isolation and characterization of novel high-CO2-requiring mutants of Chlamydomonas reinhardtii.
- Wang Lianyong,Yamano Takashi,Kajikawa Masataka,Hirono Masafumi,Fukuzawa Hideya
- Photosynthesis research, 2014-02-19
- … The photosynthetic CO2-exchange activities of these mutants were significantly decreased compared with that of wild-type cells, and accumulation of HLA3 and both LCIA and HLA3 were absent in mutants H24 and H82, respectively. …
- NAID 120005385881
- Differential Apoptotic and Proliferative Activities of Wild-type FOXL2 and Blepharophimosis-ptosis-epicanthus Inversus Syndrome (BPES)-associated Mutant FOXL2 Proteins
- KIM Jae-Hong,BAE Jeehyeon
- The journal of reproduction and development 60(1), 14-20, 2014-02
- NAID 40019997003
- Involvement of Val 315 located in the C-terminal region of thermolysin in its expression in Escherichia coli and its thermal stability.
- Kojima Kenji,Nakata Hiroki,Inouye Kuniyo
- Biochimica et biophysica acta -Proteins and Proteomics 1844(2), 330-338, 2014-02
- … The variants substituted with hydrophobic amino acids such as Leu and Ile were almost the same as wild-type thermolysin (WT) in the expression amount, α-helix content, and stability. …
- NAID 120005359199
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