tumor necrosis factor ligand superfamily member 15

腫瘍壊死因子リガンドスーパーファミリーメンバー15

WordNet

1. be a contributing factor; "make things factor into a companys profitability"
2. any of the numbers (or symbols) that form a product when multiplied together
3. an independent variable in statistics
4. anything that contributes causally to a result; "a number of factors determined the outcome"
5. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
6. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
7. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
8. a concept whose truth can be proved; "scientific hypotheses are not facts"
9. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
10. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
11. anything that belongs to a set or class; "snakes are members of the class Reptilia"; "members of the opposite sex"
12. one of the persons who compose a social group (especially individuals who have joined and participate in a group organization); "only members will be admitted"; "a member of the faculty"; "she was introduced to all the members of his family" (同)fellow member
13. an organization that is a member of another organization (especially a state that belongs to a group of nations); "the library was a member of the interlibrary loan association"; "Canada is a member of the United Nations"
14. (biology) a taxonomic group ranking below an order but above a family
15. the localized death of living cells (as from infection or the interruption of blood supply) (同)mortification, gangrene, sphacelus

PrepTutorEJDIC

1. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
2. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
3. (集団の)『一員』,会員,メンバー《+『of』+『名』》 / 《またM-》国会議員 / (数式の)項,辺 / 《文》身体の一部;(特に)手,足 / 《遠回しに》男根
4. 壊疽(えそ)

UpToDate Contents

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• 1. 炎症性腸疾患における遺伝的要因 genetic factors in inflammatory bowel disease
• 2. 腫瘍壊死因子α阻害剤および抗酸菌感染 tumor necrosis factor alpha inhibitors and mycobacterial infections
• 3. 腫瘍壊死因子α阻害剤：細菌、ウイルス、および真菌感染のリスク tumor necrosis factor alpha inhibitors risk of bacterial viral and fungal infections
• 4. 腫瘍壊死因子α（TNF-α）阻害剤：悪性腫瘍のリスク tumor necrosis factor alpha inhibitors risk of malignancy
• 5. 腫瘍壊死因子α（TNF-α）阻害剤：抗体、自己抗体、および自己免疫疾患の誘導 tumor necrosis factor alpha inhibitors induction of antibodies autoantibodies and autoimmune diseases

English Journal

• Secretion, blood levels and cutaneous expression of TL1A in psoriasis patients.

• Pedersen AE1, Schmidt EG1, Sørensen JF1, Faber C1, Nielsen BS2, Holmstrøm K2, Omland SH3, Tougaard P1, Skov S4, Bang B3.
• APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.APMIS.2015 Jul;123(7):547-55. doi: 10.1111/apm.12385. Epub 2015 Apr 24.
• TL1A is a TNF-like cytokine which has been shown to co-stimulate TH1 and TH17 responses during chronic inflammation. The expression of this novel cytokine has been investigated in inflammatory disorders like rheumatoid arthritis and inflammatory bowel disease, but little is known about expression an
• PMID 25908025

• Human primary biliary cirrhosis-susceptible allele of rs4979462 enhances TNFSF15 expression by binding NF-1.

• Hitomi Y1, Kawashima M, Aiba Y, Nishida N, Matsuhashi M, Okazaki H, Nakamura M, Tokunaga K.
• Human genetics.Hum Genet.2015 Jul;134(7):737-47. doi: 10.1007/s00439-015-1556-3. Epub 2015 Apr 22.
• A genome-wide association study (GWAS) identified tumor necrosis factor superfamily member 15 (TNFSF15) as the strongest associated gene with susceptibility to primary biliary cirrhosis (PBC) outside the HLA loci in the Japanese population. However, causal functional variants of the TNFSF15 locus an
• PMID 25899471

• The TNF-family ligand TL1A and its receptor DR3 promote T cell-mediated allergic immunopathology by enhancing differentiation and pathogenicity of IL-9-producing T cells.

• Richard AC1, Tan C2, Hawley ET1, Gomez-Rodriguez J3, Goswami R4, Yang XP5, Cruz AC1, Penumetcha P1, Hayes ET1, Pelletier M1, Gabay O1, Walsh M6, Ferdinand JR7, Keane-Myers A8, Choi Y6, O'Shea JJ5, Al-Shamkhani A9, Kaplan MH4, Gery I2, Siegel RM10, Meylan F1.
• Journal of immunology (Baltimore, Md. : 1950).J Immunol.2015 Apr 15;194(8):3567-82. doi: 10.4049/jimmunol.1401220. Epub 2015 Mar 18.
• The TNF family cytokine TL1A (Tnfsf15) costimulates T cells and type 2 innate lymphocytes (ILC2) through its receptor DR3 (Tnfrsf25). DR3-deficient mice have reduced T cell accumulation at the site of inflammation and reduced ILC2-dependent immune responses in a number of models of autoimmune and al
• PMID 25786692

Japanese Journal

• Blockade of the 4-1BB Pathway Attenuates Graft Arterial Disease in Cardiac Allografts

• International Heart Journal 49(1), 105-118, 2008
• NAID 130000068976

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★リンクテーブル★

リンク元	「腫瘍壊死因子リガンドスーパーファミリーメンバー15」
関連記事	「superfamily」「fact」「factor」「tumor」「member」

「腫瘍壊死因子リガンドスーパーファミリーメンバー15」

　　[★]

英

tumor necrosis factor ligand superfamily member 15

「superfamily」

　　[★] (機能は異なるが構造や配列が似た遺伝子の集団)スーパーファミリー、(分類学;動物の)上科

関

family group、supergene family

　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「tumor」

　　[★]

• n.

• 腫瘍、腫瘤、腫脹

　

「member」

　　[★]

• メンバー