thymic carcinoma

WordNet

1. any malignant tumor derived from epithelial tissue; one of the four major types of cancer

PrepTutorEJDIC

1. がん,がん腫

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2016/06/02 03:10:54」(JST)

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Thymic carcinoma
Thymic carcinoma seen on CT.
Classification and external resources
Specialty	Oncology
ICD-10	C37
ICD-9-CM	164.0
MeSH	D013945

Thymic carcinoma is a rare type of thymus gland cancer. It usually spreads, has a high risk of recurrence, and has a poor survival rate. Thymic carcinoma is divided into subtypes, depending on the types of cells in which the cancer began. Also called type C thymoma.

Pathology

Digital slides

• JRC:3079 Thymic carcinoma (NOS)
• JRC:3191 Thymic carcinoma (NOS)
• JRC:19002 Thymic carcinoma (NOS)
• JRC:14579 Thymic carcinoma with basaloid features
• JRC:14602 Thymic carcinoma with clear cell changes

External links

• Foundation for Thymic Cancer Research -Fostering Awareness and Research, Dedicated to Helping Patients with Thymic Cancers
• Thymic carcinoma entry in the public domain NCI Dictionary of Cancer Terms

 This article incorporates public domain material from the U.S. National Cancer Institute document "Dictionary of Cancer Terms".

UpToDate Contents

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• 1. 胸腺腫および胸腺癌の臨床症状およびマネージメント clinical presentation and management of thymoma and thymic carcinoma
• 2. 胸腺神経内分泌（カルチノイド）腫瘍 thymic neuroendocrine carcinoid tumors
• 3. 縦隔腫瘍の病理 pathology of mediastinal tumors
• 4. 重症筋無力症の診断 diagnosis of myasthenia gravis
• 5. 前部縦隔の腫瘤性病変 anterior mediastinal mass lesions

English Journal

• Mediastinal seminoma associated with multilocular thymic cyst.

• Inui M1,2, Nitadori JI3, Tajima S4, Yoshioka T3, Hiyama N3, Watadani T5, Shinozaki-Ushiku A4, Nagayama K3, Anraku M3, Sato M3, Fukayama M4, Nakajima J3.
• Surgical case reports.Surg Case Rep.2017 Dec;3(1):7. doi: 10.1186/s40792-016-0278-7. Epub 2017 Jan 5.
• PMID 28054283

• Volume-based quantification using dual-energy computed tomography in the differentiation of thymic epithelial tumours: an initial experience.

• Chang S1, Hur J2, Im DJ1, Suh YJ1, Hong YJ1, Lee HJ1, Kim YJ1, Han K3, Kim DJ4, Lee CY4, Shin HY5, Choi BW1.
• European radiology.Eur Radiol.2017 May;27(5):1992-2001. doi: 10.1007/s00330-016-4542-9. Epub 2016 Aug 23.
• PMID 27553938

• Clinical, imaging, and follow-up observations of patients with anti-GABAB receptor encephalitis.

• Qiao S1, Zhang YX2, Zhang BJ2, Lu RY2, Lai QL1,2, Chen LH1, Wu J1.
• The International journal of neuroscience.Int J Neurosci.2017 May;127(5):379-385. doi: 10.1080/00207454.2016.1176922. Epub 2016 May 1.
• PMID 27066808

Japanese Journal

• Combination Chemotherapy with Doxorubicin, Vincristine, Cyclophosphamide, and Platinum Compounds for Advanced Thymic Carcinoma

• Agatsuma Toshihiko,Koizumi Tomonobu,Kanda Shintaro,Ito Michiko,Urushihata Kazuhisa,Yamamoto Hiroshi,Hanaoka Masayuki,Kubo Keishi
• JOURNAL OF THORACIC ONCOLOGY 6(12), 2130-2134, 2012-10-01
• … Introduction: Thymic carcinoma is a rare epithelial neoplasm that tends to be aggressive and metastasize widely. … The optimal chemotherapy for unresectable advanced thymic carcinoma has not yet been established because of its rare occurrence. …
• NAID 120004724756

• 臨床経験 血管合併切除により完全切除した胸腺癌

• 山木 実,則行 敏生,濱本 正樹 他
• 胸部外科 65(6), 489-492, 2012-06-00
• NAID 40019333996

Related Links

• Thymoma and Thymic Carcinoma Treatment (PDQ ...

Expert-reviewed information summary about the treatment of thymoma and thymic carcinoma. ... Physical exam and history: An exam of the body to check general signs of health, including checking for signs of disease, such as ...

• Thymic

Our Mission To support patients with thymic cancer by fostering research and awareness of this aggressive, difficult-to-treat, and little-understood ... What is Thymic Cancer? Thymic cancer is a cancer of the thymus gland or thymic ...

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★リンクテーブル★

リンク元	「胸腺腫」「胸腺癌」
関連記事	「thymic」「thymi」

「胸腺腫」

　　[★]

英

thymoma, thymomas

関

胸腺、縦隔腫瘍

概念

• 上縦隔の前部、前縦隔の前部に発生
• 胸腺固有の上皮細胞が腫瘍化したもの。precursor T cell(thymocytes)も存在することがあるが、悪性ではない。

分類

• begign or encapsulated thymoma

• malignant thymoma
• type I: cytologically benign but biologically aggressive and capable of local invasion and, rarely, distant spread
• type II: also called thymic carcinoma: cytologically malignant with all of the features of cancer and comparable behavior

HIM. e89

型	組織型	割合,%	予後(10-year disease-free survival), %
A	medullary thymoma	8	100
AB	mixed thymoma	17	100
B1	predominantly cortical thymoma	27	83
B2	cortical thymoma	8	83
B3	well-differentiated thymic carcinoma	12	36
C	thymic carcinoma	28	28

病因

• 不明なことが多い。EBウイルスが関わっているかもしれない

疫学

• 胸腺腫は希であって、悪性のものはさらに希
• 全縦隔腫瘍の20-30%を占める。
• どの年齢にも起こりうるが、とりわけ中年に後発する。平均50歳代。

症状

• 30%：無症状。
• 30-40%：CTでとらえられ、咳嗽、胸痛、呼吸困難、上大静脈症候群などの周胸臓器圧迫症状
• 残り：全身病の合併

• 左反回神経を圧迫して嗄声もありうる、と思う

合併症

• 重症筋無力症(重症筋無力症の15-20%で、胸腺腫が見つかる)
• 赤芽球癆 pure red cell aplasia PRCA
• 低γグロブリン血症/無γグロブリン血症
• 全身性エリテマトーデス
• 多発性筋炎 (IMD.752)
• クッシング症候群 (IMD.752)
• 非胸腺腫様

症例

• 40歳の女性。夕方になると、ものが二重に見える(複視)ことを主訴に来院した。眼瞼下垂を認める。血液検査では網赤血球の減少を認める。

参考

• 1. 15-year-old boy with noninvasive cystic thymoma

http://www.ajronline.org/cgi/content-nw/full/186/4/1176/FIG5

• 2.

http://telomelysin.com/article/52766550.html

• 3. Imaging of Cystic Masses of the Mediastinum1

http://radiographics.rsna.org/content/22/suppl_1/S79.full

「胸腺癌」

　　[★]

英

thymic carcinoma

関

胸腺腫

「thymic」

　　[★]

• adj.

• 胸腺の

関

thymi、thymus、thymus gland

「thymi」

　　[★]

胸腺

関

thymic、thymus、thymus gland