WordNet
- place at intervals; "Space the interviews so that you have some time between the different candidates"
- an empty area (usually bounded in some way between things); "the architect left space in front of the building"; "they stopped at an open space in the jungle"; "the space between his teeth"
- the unlimited expanse in which everything is located; "they tested his ability to locate objects in space"; "the boundless regions of the infinite" (同)infinite
- a blank character used to separate successive words in writing or printing; "he said the space is the most important character in the alphabet" (同)blank
- a blank area; "write your name in the space provided" (同)blank space, place
- an area reserved for some particular purpose; "the laboratorys floor space"
- one of the areas between or below or above the lines of a musical staff; "the spaces are the notes F-A-C-E"
- the time between occurrences of a repeating event; "some women do not control the spacing of their children"
- the property possessed by an array of things that have space between them (同)spatial_arrangement
- arranged with spaces between; often used as a combining form; "widely spaced eyes"
PrepTutorEJDIC
- 〈U〉『空間』,広がり / 〈U〉『宇宙』,地球の大気圏外(outer space) / 〈C〉〈U〉『間隔』,距離;《しばしば複数形で》空地 / 〈C〉(特定目的のための)『場所』 / 〈U〉《しばしばa~》時間 / 〈C〉〈U〉スペース,余白,余地 / 〈C〉線間(譜表において五線の間の部分) / …‘を'間隔をおいて配置する《+『out』+『名,』+『名』+『out』》
- 《所有・所属》…『の』,…のものである,…に属する・《材料・要素》…『でできた』,から成る・《部分》…『の』[『中の』] ・《数量・単位・種類を表す名詞に付いて》…の・《原因・動機》…『で』,のために(because of) ・《主格関係》…『の』,による,によって・《目的格関係》…『を』,の・《同格関係》…『という』・《関係・関連》…『についての』[『の』],の点で・《抽象名詞などと共に》…の[性質をもつ] ・《『It is』+『形』+『of』+『名』+『to』 doの形で,ofの後の名詞を意味上の主語として》・《分離》…『から』・《起原・出所》…『から』[『の』](out of) ・《『名』+『of』+『a』(『an』)+『名』の形で》…のような・《『名』+『of』+『mine』(『yours, his』など独立所有格)の形で》…の…・《時》(1)《副詞句を作って》…に《形容詞句を作って》…の・《時刻》《米》…前(to,《米》before)
- スペースをあけること,間隔をとること / (印刷された行・語・文の)スペース,間隔
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2017/10/11 10:44:15」(JST)
[Wiki en表示]
Perisinusoidal space |
Sinusoid of a rat liver with fenestrated endothelial cells. Fenestrae are approx 100 nm diameter, and the sinusoidal width 5 µm. Scanning electron micrograph by Robin Fraser, University of Otago.
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Basic liver structure
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Details |
Identifiers |
Latin |
spatium perisinusoideum |
Code |
TH H3.04.05.0.00012 |
TH |
H3.04.05.0.00012 |
Anatomical terminology
[edit on Wikidata]
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The perisinusoidal space (or space of Disse) is a location in the liver between a hepatocyte and a sinusoid. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing proteins and other plasma components from the sinusoids to be absorbed by the hepatocytes. Fenestration and discontinuity of the endothelium, as well as its basement membrane,[1] facilitates this transport.[2] This space may be obliterated in liver disease, leading to decreased uptake by hepatocytes of nutrients and wastes such as bilirubin.
The perisinusoidal space also contains hepatic stellate cells (also known as cells of Ito), which store fat or fat soluble vitamins including vitamin A). A variety of insults that cause inflammation can result in the cells transforming into myofibroblasts, resulting in collagen production, fibrosis, and cirrhosis.
The Space of Disse was named after German anatomist Joseph Disse (1852–1912).[3]
References
- ^ Mescher, Anthony L. "The Circulatory System." Junquiera's Basic Histology. 12th Ed. New York: McGraw-Hill, 2010. Print. 197.
- ^ Robbins, Stanley L.; Cotran, Ramzi S.; Kumar, Vinay; Collins, Tucker (1999). Robbins pathologic basis of disease. Philadelphia: Saunders. ISBN 0-7216-7335-X.
- ^ Haubrich WS (2004). "Disse of the space of Disse". Gastroenterology. 127 (6): 1684. PMID 15578505. doi:10.1053/j.gastro.2004.10.021.
External links
- UIUC Histology Subject 1317
- Histology image: 22103loa – Histology Learning System at Boston University - "Ultrastructure of the Cell: hepatocytes and sinusoids, sinusoid and space of Disse"
- Histology image: 15204loa – Histology Learning System at Boston University - "Liver, Gall Bladder, and Pancreas: liver; sinusoids and Kupffer cells"
- Anatomy photo: digestive/mammal/liver5/liver7 - Comparative Organology at University of California, Davis - "Mammal, liver (EM, Low)"
Anatomy of the liver, pancreas and biliary tree
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Liver |
- Bare area
- Cantlie line
- Ligamentum venosum
- Porta hepatis
- Round ligament
- Lobes
- Left
- Right (Caudate
- Quadrate)
- Fibrous capsule of Glisson
- Perisinusoidal space
- Liver sinusoid
- Portal triad
- Lobules of liver
- Liver segment
- Microanatomy
- Hepatocyte
- Hepatic stellate cell
- Kupffer cell
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Biliary tract |
Bile ducts |
- Intrahepatic bile ducts
- Bile canaliculus
- Canals of Hering
- Interlobular
- Left hepatic duct
- Right hepatic duct
- Common hepatic duct
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Gallbladder |
- Cystic duct
- Common bile duct
- Ampulla of Vater
- Cells
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Pancreas |
- Gross
- Tail
- Body
- Neck
- Head (Uncinate process)
- Ducts
- Microanatomy
- Pancreatic islets
- Centroacinar cell
- Stellate cell
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UpToDate Contents
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English Journal
- A multiscale modelling approach to assess the impact of metabolic zonation and microperfusion on the hepatic carbohydrate metabolism.
- Berndt N1, Horger MS2, Bulik S1,3, Holzhütter HG1.
- PLoS computational biology.PLoS Comput Biol.2018 Feb 15;14(2):e1006005. doi: 10.1371/journal.pcbi.1006005. eCollection 2018 Feb.
- PMID 29447152
- Effect of shear stress on the migration of hepatic stellate cells.
- Sera T1, Sumii T2, Fujita R3, Kudo S4.
- In vitro cellular & developmental biology. Animal.In Vitro Cell Dev Biol Anim.2018 Jan;54(1):11-22. doi: 10.1007/s11626-017-0202-x. Epub 2017 Nov 9.
- PMID 29124511
- Human hepatic stellate cell isolation and characterization.
- Shang L1, Hosseini M2, Liu X3, Kisseleva T3, Brenner DA4,5.
- Journal of gastroenterology.J Gastroenterol.2018 Jan;53(1):6-17. doi: 10.1007/s00535-017-1404-4. Epub 2017 Nov 1.
- PMID 29094206
Japanese Journal
- Extravasated platelet aggregation in the livers of rats with drug-induced hepatic sinusoidal obstruction syndrome
- Silica nanoparticle-induced toxicity in mouse lung and liver imaged by electron microscopy
- Extravasated platelet aggregation in liver zone 3 may correlate with the progression of sinusoidal obstruction syndrome following living donor liver transplantation: A case report
Related Pictures
★リンクテーブル★
[★]
- 英
- perisinusoidal space
- ラ
- spatium perisinusoideum
- 同
- ディッセ腔, Disse腔, Disse space, space of Disse
- 関
- 類洞周囲腔
[★]
n.
vt.
- ex. oral doses should be spaced wqually to maintein a continuous high concentraction of iron in plasma.
- 関
- alveus、cavity、cosmic、room、universe、ventriculi、ventriculus
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