WordNet
- place at intervals; "Space the interviews so that you have some time between the different candidates"
- an empty area (usually bounded in some way between things); "the architect left space in front of the building"; "they stopped at an open space in the jungle"; "the space between his teeth"
- the unlimited expanse in which everything is located; "they tested his ability to locate objects in space"; "the boundless regions of the infinite" (同)infinite
- a blank character used to separate successive words in writing or printing; "he said the space is the most important character in the alphabet" (同)blank
- a blank area; "write your name in the space provided" (同)blank space, place
- an area reserved for some particular purpose; "the laboratorys floor space"
- one of the areas between or below or above the lines of a musical staff; "the spaces are the notes F-A-C-E"
- the time between occurrences of a repeating event; "some women do not control the spacing of their children"
- the property possessed by an array of things that have space between them (同)spatial_arrangement
- arranged with spaces between; often used as a combining form; "widely spaced eyes"
PrepTutorEJDIC
- 〈U〉『空間』,広がり / 〈U〉『宇宙』,地球の大気圏外(outer space) / 〈C〉〈U〉『間隔』,距離;《しばしば複数形で》空地 / 〈C〉(特定目的のための)『場所』 / 〈U〉《しばしばa~》時間 / 〈C〉〈U〉スペース,余白,余地 / 〈C〉線間(譜表において五線の間の部分) / …‘を'間隔をおいて配置する《+『out』+『名,』+『名』+『out』》
- スペースをあけること,間隔をとること / (印刷された行・語・文の)スペース,間隔
- 鉱泉,温泉 / 温泉場
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/06/30 16:47:46」(JST)
[Wiki en表示]
Perisinusoidal space |
Sinusoid of a rat liver with fenestrated endothelial cells. Fenestrae are approx 100 nm diameter, and the sinusoidal width 5 µm. Scanning electron micrograph by Robin Fraser, University of Otago.
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Basic liver structure
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Details |
Latin |
spatium perisinusoideum |
Identifiers |
Code |
TH H3.04.05.0.00012 |
Anatomical terminology |
The perisinusoidal space (or space of Disse) is a location in the liver between a hepatocyte and a sinusoid. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing proteins and other plasma components from the sinusoids to be absorbed by the hepatocytes. Fenestration and discontinuity of the endothelium, as well as its basement membrane,[1] facilitates this transport.[2] This space may be obliterated in liver disease, leading to decreased uptake by hepatocytes of nutrients and wastes (like bilirubin, for example).
The Space of Disse also contains Ito cells, also called hepatic stellate cells, which store fat or fat soluble vitamins (like vitamin A). A variety of insults that cause inflammation can result in Ito cells transforming to myofibroblasts, resulting in collagen production, fibrosis, and cirrhosis.
The Space of Disse was named after German anatomist Joseph Disse (1852–1912).[3]
References
- ^ Mescher, Anthony L. "The Circulatory System." Junquiera's Basic Histology. 12th Ed. New York: McGraw-Hill, 2010. Print. 197.
- ^ Robbins, Stanley L.; Cotran, Ramzi S.; Kumar, Vinay; Collins, Tucker (1999). Robbins pathologic basis of disease. Philadelphia: Saunders. ISBN 0-7216-7335-X.
- ^ Haubrich WS (2004). "Disse of the space of Disse". Gastroenterology 127 (6): 1684. doi:10.1053/j.gastro.2004.10.021. PMID 15578505.
External links
- UIUC Histology Subject 1317
- Histology image: 22103loa – Histology Learning System at Boston University - "Ultrastructure of the Cell: hepatocytes and sinusoids, sinusoid and space of Disse"
- Histology image: 15204loa – Histology Learning System at Boston University - "Liver, Gall Bladder, and Pancreas: liver; sinusoids and Kupffer cells"
- Anatomy photo: digestive/mammal/liver5/liver7 - Comparative Organology at University of California, Davis - "Mammal, liver (EM, Low)"
Accessory digestive glands
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Liver |
- Bare area of the liver
- Ligamentum venosum
- Porta hepatis
- Round ligament of liver
- Lobes
- Left
- Right (Caudate lobe
- Quadrate)
- Fibrous capsule of Glisson
- Perisinusoidal space
- Liver sinusoid
- Periportal space
- Portal triad
- Lobules of liver
- Microanatomy
- Hepatocyte
- Hepatic stellate cell
- Kupffer cell
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Biliary tract |
Bile ducts |
- Intrahepatic bile ducts
- Bile canaliculus
- Canals of Hering
- Interlobular bile ducts
- Left hepatic duct
- Right hepatic duct
- Common hepatic duct
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Gallbladder |
- Cystic duct
- Common bile duct
- Ampulla of Vater
- Cells
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Pancreas |
- Gross
- Tail
- Body
- Neck
- Head (Uncinate process)
- Ducts
- Microanatomy
- Islets of Langerhans
- Centroacinar cell
- stellate cell
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Index of digestion
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Description |
- Anatomy
- Physiology
- Development
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Disease |
- Congenital
- Neoplasms and cancer
- Inflammatory bowel disease
- Gluten sensitivity
- Other
- Symptoms and signs
- Blood tests
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Treatment |
- Procedures
- Drugs
- anabolic steroids
- antacids
- diarrhoea and infection
- bile and liver
- functional gastrointestinal disorders
- laxatives
- peptic ulcer and reflux
- nausea and vomiting
- other
- Surgery
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UpToDate Contents
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English Journal
- Morphometric alterations, steatosis, fibrosis and active caspase-3 detection in carbamate bendiocarb treated rabbit liver.
- Petrovova E, Purzyc H, Mazensky D, Luptakova L, Torma N, Sopoliga I, Sedmera D.SourceDepartment of Anatomy, Histology and Physiology, University of Veterinary Medicine and Pharmacy, Komenskeho 73, 04011, Kosice, Slovakia.
- Environmental toxicology.Environ Toxicol.2013 Jul 9. doi: 10.1002/tox.21887. [Epub ahead of print]
- Increasing use of pesticides all over the world makes it necessary to reveal the toxic risk in populations of nontargeted organisms. Bendiocarb is one of the 12 insecticides recommended by the World Health Organization for use in malaria control in Africa, and is used against a variety of insects. T
- PMID 23836410
- Oxaliplatin-related sinusoidal obstruction syndrome mimicking metastatic liver tumors.
- Arakawa Y, Shimada M, Utsunomya T, Imura S, Morine Y, Ikemoto T, Hanaoka J, Sugimoto K, Bando Y.SourceDepartment of Surgery, Institute of Health Biosciences, University of Tokushima.
- Hepatology research : the official journal of the Japan Society of Hepatology.Hepatol Res.2013 Jun;43(6):685-9. doi: 10.1111/j.1872-034X.2012.01114.x.
- A 40-year-old woman who had undergone a curative low anterior resection for advanced rectal cancer was admitted to our hospital. She had been administrated oxaliplatin-based chemotherapy as postoperative adjuvant chemotherapy. The contrast-enhanced computed tomography revealed three hypovascular tum
- PMID 23730707
Japanese Journal
- Epigenetic Modifications in Hepatic Stellate Cells Contribute to Liver Fibrosis
- 腎不全,肝不全が急速に進行したLight Chain Deposition Disease(LCDD)の1症例
- Tubulovesicle Network in the Intercellular Space between Hepatocytes of Laboratory Animals : A Freeze-Fracture Study
Related Links
- The space of Disse (or perisinusoidal space) is a location in the liver between a hepatocyte and a sinusoid. It contains the blood plasma. Microvilli of hepatocytes extend into this space, allowing proteins and other plasma components from the ...
Related Pictures
★リンクテーブル★
[★]
- 英
- perisinusoidal space
- ラ
- spatium perisinusoideum
- 同
- ディッセ腔, Disse腔, Disse space, space of Disse
- 関
- 類洞周囲腔
[★]
n.
vt.
- ex. oral doses should be spaced wqually to maintein a continuous high concentraction of iron in plasma.
- 関
- alveus、cavity、cosmic、room、universe、ventriculi、ventriculus
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