WordNet

divide into parts, pieces, or sections; "The Arab peninsula was partitioned by the British" (同)partition off
separate or apportion into sections; "partition a room off" (同)zone
(computer science) the part of a hard disk that is dedicated to a particular operating system or application and accessed as a single unit
a vertical structure that divides or separates (as a wall divides one room from another) (同)divider
(anatomy) a structure that separates areas in an organism
send a message from one computer to another to check whether it is reachable and active; "ping your machine in the office"
a sharp high-pitched resonant sound (as of a sonar echo or a bullet striking metal)
contact, usually in order to remind of something; "Ill ping my accountant--April 15 is nearing"
hit with a pinging noise; "The bugs pinged the lamp shade"
make a short high-pitched sound; "the bullet pinged when they struck the car"
a tentative insight into the natural world; a concept that is not yet verified but that if true would explain certain facts or phenomena; "a scientific hypothesis that survives experimental testing becomes a scientific theory"; "he proposed a fresh theory (同)possibility, theory
a proposal intended to explain certain facts or observations
(from potential of Hydrogen) the logarithm of the reciprocal of hydrogen-ion concentration in gram atoms per liter; provides a measure on a scale from 0 to 14 of the acidity or alkalinity of a solution (where 7 is neutral and greater than 7 is more basic and less than 7 is more acidic); (同)pH scale

PrepTutorEJDIC

〈U〉(‥の)分割,区分《+『of』麥『名』》 / 〈C〉(分割された)部分 / 〈C〉仕切り壁 / (…に)…‘を'分割する,分配する《+『名』+『into』+『名』》 / …‘を'仕切る,区切る《+『off』+『名,』+『名』+『off』》
(小銃弾などの)ピュー(ブーン)という音 / ピュー(ブーン)と音がする
仮説,仮定,前提
ペーハー(水素イオン濃度指数)

UpToDate Contents

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1. Chapter 11A：腎臓での水排泄 chapter 11a renal hydrogen excretion
2. Chapter 10C：細胞内pH chapter 10c intracellular ph
3. Chapter 11C：動脈血pHが換気に及ぼす影響 chapter 11c effect of arterial ph on ventilation
4. Chapter 11B：腎臓の水排泄調節 chapter 11b regulation of renal hydrogen excretion
5. Chapter 13B：尿浸透圧とpHの意義 chapter 13b meaning of urine osmolality and ph

English Journal

A new PAMPA model proposed on the basis of a synthetic phospholipid membrane.

Yu H1, Wang Q2, Sun Y2, Shen M2, Li H3, Duan Y2.
PloS one.PLoS One.2015 Feb 3;10(2):e0116502. doi: 10.1371/journal.pone.0116502. eCollection 2015.
The purpose of this work was to investigate the synthetic phospholipid dependence of permeability measured by parallel artificial membrane permeability assay (PAMPA) method. Three phospholipids with hydrophobic groups of different lengths and phosphorylcholine as the hydrophilic group were concisely
PMID 25647086

Transport mechanisms for soy isoflavones and microbial metabolites dihydrogenistein and dihydrodaidzein across monolayers and membranes.

Kobayashi S1, Shinohara M, Nagai T, Konishi Y.
Bioscience, biotechnology, and biochemistry.Biosci Biotechnol Biochem.2013;77(11):2210-7. Epub 2013 Nov 7.
Isoflavone data concerning the metabolism and permeability on intestinal epithelial cells are scarce, particularly for microbial isoflavone metabolites. This study evaluates the absorption mechanisms for the isoflavones, genistein and daidzein, and their microbial metabolites, dihydrogenistein (DHG)
PMID 24200780

Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes.

Kobayashi S1, Nagai T, Konishi Y, Tanabe S, Morimoto K, Ogihara T.
The Journal of pharmacy and pharmacology.J Pharm Pharmacol.2012 Jan;64(1):52-60. doi: 10.1111/j.2042-7158.2011.01374.x. Epub 2011 Nov 10.
OBJECTIVES: We recently reported that flavanone aglycones (hesperetin, naringenin and eriodictyol) are efficiently absorbed via proton-coupled active transport, in addition to transcellular passive diffusion, in Caco-2 cells. Here, we aimed to evaluate in detail the absorption mechanisms of these fl
PMID 22150672

Japanese Journal

Transport Mechanisms for Soy Isoflavones and Microbial Metabolites Dihydrogenistein and Dihydrodaidzein Across Monolayers and Membranes

KOBAYASHI Shoko,SHINOHARA Miki,NAGAI Toshitada,KONISHI Yutaka
Bioscience, Biotechnology, and Biochemistry, 2013
… The data suggest that genistein, DHG and DHD were efficiently transported by passive diffusion according to the pH-partition hypothesis. …
NAID 130003381920

トランスポーターを介した薬物吸収の分子機構論的研究

玉井郁巳
藥學雜誌 117(7), 415-434, 1997-07-25
… A rat intestinal monocarboxylic acid-proton cotransporter, MCT1,and an anion antiporter, AE2,were suggested to contribute to the pH-dependent intestinal absorption of monocarboxylic acids such as benzoic acid, lactic acid, nicotinic acid, and valproic acid. …
NAID 110003649098

Carrier-Mediated Uptake of Nicotinic Acid by Rat Intestinal Brush-Border Membrane Vesicles and Relation to Monocarboxylic Acid Transport

SIMANJUNTAK Matheus Timbul,TAMAI Ikumi,TERASAKI Tetsuya,TSUJI Akira
Journal of pharmacobio-dynamics 13(5), 301-309, 1990-05
… The osmolarity sensitive uptake by BBMV showed a remarkable overshoot phenomenon in the presence of an inward-directed H^+ gradient (pH_<in>=7.5,pH_<out>=6.0). … The remarkable pH-dependence of the initial uptake showing an increase of the uptake rate with decreasing the extravesicular pH disappeared completely in the presence of a structural analogue, isonicotinic acid, at pH below 6.5. …
NAID 110003637192