p-hydroxyphenylethylamine
チラミン
WordNet
- send a message from one computer to another to check whether it is reachable and active; "ping your machine in the office"
- a sharp high-pitched resonant sound (as of a sonar echo or a bullet striking metal)
- contact, usually in order to remind of something; "Ill ping my accountant--April 15 is nearing"
- hit with a pinging noise; "The bugs pinged the lamp shade"
- make a short high-pitched sound; "the bullet pinged when they struck the car"
- the 16th letter of the Roman alphabet (同)p
PrepTutorEJDIC
- (小銃弾などの)ピュー(ブーン)という音 / ピュー(ブーン)と音がする
- parking
- phosphorusの化学記号
English Journal
- Solanidane and iminosolanidane alkaloids from Solanum campaniforme.
- Torres MC1, Jorge RJ, Ximenes RM, Alves NT, Santos JV, Marinho AD, Monteiro HS, Toyama MH, Braz-Filho R, Silveira ER, Pessoa OD.
- Phytochemistry.Phytochemistry.2013 Dec;96:457-64. doi: 10.1016/j.phytochem.2013.09.007. Epub 2013 Sep 26.
- From the leaves of Solanum campaniforme (Solanaceae), eight solanidane alkaloids were isolated, four of which contain a p-hydroxyphenylethylamine unit. Their structures were established as: 22β,23β-epoxy-solanida-1,4-dien-3-one; 22α,23α-epoxy-10-epi-solanida-1,4,9-trien-3-one; 22α,23α-epoxy-so
- PMID 24075572
- YUA001, a novel aldose reductase inhibitor isolated from alkalophilic Corynebacterium sp. YUA25. II. Chemical modification and biological activity.
- Sun WS1, Lee HS, Park JM, Kim SH, Yu JH, Kim JH.
- The Journal of antibiotics.J Antibiot (Tokyo).2001 Oct;54(10):827-30.
- A series of novel N-substituted tyramine (2-p-hydroxyphenylethylamine) derivatives (1 to approximately 11) were synthesized and evaluated for their inhibitory activity against pig kidney aldose reductase (EC 1, 1, 1, 21). Of these compounds, N-2-p-hydroxyphenylethyl maleamic acid (10) exhibits the s
- PMID 11776438
- Preparation of antibodies to catecholamines and metabolites--syntheses of various immunogens and characterization of the resulting antibodies.
- Diener U, Knoll E, Wisser H.
- Clinica chimica acta; international journal of clinical chemistry.Clin Chim Acta.1981 Jan 8;109(1):1-11.
- The synthesis of antigens of the haptens p-tyramine, octopamine, synephrine, dopamine, normetanephrine, beta-(3,4-dichlorophenyl)-ethylamine and 3-fluoro-tyramine is described. The coupling of the haptens to the carrier protein was performed either via the side chain by means of succinic anhydride,
- PMID 7471484
Related Links
- p-Hydroxyphenylethylamine - chemical information, properties, structures, articles, patents and more chemical data. ... Find hydroxyphenylethylamine at C/D/N Isotopes Manufacturer Canada C/D/N Isotopes has developed the world ...
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★リンクテーブル★
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- 英
- tyramine
- 同
- p-ヒドロキシフェニルエチルアミン p-hydroxyphenylethylamine
- 関
- MAO inhibitor
特徴
- ノルアドレナリンの放出を促進する→レセルピンで処理されると作用が消失
- チーズ、赤ワイン、ビール、にしん、鶏肝、チョコレートに多く含まれる
薬理作用
- シナプス前膜からノルアドレナリンの分泌を促すことによる
適応
- →β受容体作動薬に取って代わられる
- →α受容体作動薬に取って代わられる
- ※ 鼻粘膜にはα受容体しかない
- 脊髄・硬膜外麻酔の低血圧に対する対処
- ナルコプシー
- 夜尿症
注意
- タキヒラキシス tachyphylaxisを起こしやすい
- コカイン、三環系抗うつ薬(imipramine, desipramine)がuptake1を抑制
- MAO阻害薬を使用している場合、チラミンが投与されると神経終末中のノルアドレナリンの分解が押さえられてシナプス小胞内の貯蔵量がまし、チラミンにより大量のノルアドレナリンが放出される→高血圧発作(クリーゼ)を起こす。
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- 時間単位
- 関
- picosecond、psec
[★]
- 10の-12乗
- 関
- pico