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1. 過敏性腸症候群に対するアロセトロン塩酸塩（Lotronex） alosetron hydrochloride lotronex for irritable bowel syndrome
2. 成人における急性咽頭炎の対症療法 symptomatic treatment of acute pharyngitis in adults
3. 早産児における非経口栄養 parenteral nutrition in premature infants
4. コーガン症候群 cogans syndrome
5. 局所麻酔剤に対するアレルギー反応 allergic reactions to local anesthetics

Ozagrel hydrochloride, a selective thromboxane A₂ synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice.

Tomishima Y, Ishitsuka Y, Matsunaga N, Nagatome M, Furusho H, Irikura M, Ohdo S, Irie T.SourceDepartment of Clinical Chemistry and Informatics, Graduate School of Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Chuo-ku, Kumamoto 862-0973, Japan.
BMC gastroenterology.BMC Gastroenterol.2013 Jan 30;13:21. doi: 10.1186/1471-230X-13-21.
BACKGROUND: Overdosed acetaminophen (paracetamol, N-acetyl-p-aminophenol; APAP) causes severe liver injury. We examined the effects of ozagrel, a selective thromboxane A2 (TXA2) synthase inhibitor, on liver injury induced by APAP overdose in mice.METHODS: Hepatotoxicity was induced to ICR male mice
PMID 23363429

Fasudil and ozagrel in combination show neuroprotective effects on cerebral infarction after murine middle cerebral artery occlusion.

Koumura A, Hamanaka J, Kawasaki K, Tsuruma K, Shimazawa M, Hozumi I, Inuzuka T, Hara H.SourceDepartment of Biofunctional Evaluation, Gifu Pharmaceutical University, Gifu, Japan.
The Journal of pharmacology and experimental therapeutics.J Pharmacol Exp Ther.2011 Jul;338(1):337-44. doi: 10.1124/jpet.110.177675. Epub 2011 Apr 14.
Rho kinase (ROCK), one of the serine/threonine kinases, is involved in pathologic conditions, and its activation causes neuronal cell death. Fasudil, a selective ROCK inhibitor, has been reported to cause increased cerebral blood flow (CBF) in the ischemic brain and protect against neuronal cell dea
PMID 21493751

[A case of migrainous infarction accompanying idiopathic thrombocytopenic purpura].

Nanri K, Niiyama K, Utsumi H, Sekine S, Katou H, Kougo K, Morihara Y, Hayashi T.SourceThird Department of Internal Medicine, Tokyo Medical University, Department of Neurology, Tokyo Medical University Hachioji Medical Center.
Rinshō shinkeigaku = Clinical neurology.Rinsho Shinkeigaku.2002 Sep;42(9):868-72.
We reported a 31 year-old man with repeated episodes of migraine at a frequency of about once a week on and after January, 2000. In January 2001, scintillating scotoma and pulsating headache appeared followed by left hemianopsia. His platelet count decreased to 80,000/microliter and high intensity a
PMID 12710087

船山麻理菜,寺崎絵里,小宮山絵梨 [他]
日本獣医師会雑誌 = Journal of the Japan Veterinary Medical Association 66(1), 52-56, 2013-01-00
NAID 40019538718

鈴木龍太,遠藤秀,藤本司,田口芳雄,榊原陽太郎,桜井孝,林龍男,三代貴康,露無松平,中村良一
脳卒中の外科 34(4), 284-288, 2006-07-31
… To obtain a standardized preventive method for SVS after SAH, the present multi-institutional cooperative clinical study of fasudil hydrochloride was conducted in 5 institutions in Kanagawa Prefecture. … Subjects were randomly categorized into 3 groups, to receive: fasudil hydrochloride (Fa, n=57); … nicardipine hydrochloride (Ni, n=32); … or ozagrel sodium (Oz, n=23). …
NAID 110004763575

Combination Therapy of Fasudil Hydrochloride and Ozagrel Sodium for Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage

中島進,TABUCHI Kazuo,SHIMOKAWA Shoko,FUKUYAMA Kouzou,MINETA Toshihiro,ABE Masamitsu
Neurologia medico-chirurgica 38(12), 805-811, 1998-12-15
くも膜下出血術後の血管攣縮に対する塩酸ファスジル、オザグレルナトリウム併用療法の有用性を確認する目的で、オザグレルナトリウム単独投与群と比較検討した。1995年9月以降の併用療法群(60症例)とそれ以前の単独投与群(57症例)の臨床成績を比較解析。症候性脳血管攣縮の発生頻度については併用療法群で少なかったが、両群間で有意差は見られなかった。しかしCTscan上の低吸収域の発生頻度は併用療法群で有意 …
NAID 110002277489