エストリオール
English Journal
- Estriol strongly inhibits DNCB-induced contact dermatitis: role of antigen-specific antibodies in pathogenesis.
- Zhang EY1, Zhu BT2.
- Endocrine connections.Endocr Connect.2014 Dec;3(4):161-72. doi: 10.1530/EC-14-0080. Epub 2014 Aug 22.
- The endogenous estrogens are important modulators of the immune system and its functions. However, their effects are rather complex and many aspects have not been studied. In this study, we used the 1-chloro-2,4-dinitrobenzene (DNCB)-induced contact dermatitis as a disease model and investigated the
- PMID 25150251
- Endocrine-disrupting chemicals in the Pearl River Delta and coastal environment: sources, transfer, and implications.
- Xu W1, Yan W, Huang W, Miao L, Zhong L.
- Environmental geochemistry and health.Environ Geochem Health.2014 Dec;36(6):1095-104. doi: 10.1007/s10653-014-9618-3. Epub 2014 May 11.
- A study was conducted to investigate the occurrence and behavior of six endocrine-disrupting chemicals (EDCs) in sewage, river water, and seawater from the Pearl River Delta (PRD). The six EDCs under study were 4-nonylphenol (NP), bisphenol A (BPA), 17α-ethynylestradiol (EE2), estrone (E2), 17β-es
- PMID 24817613
- Vaginal estriol-lactobacilli combination (Gynoflor®) therapy and sexual quality of life in aromatase inhibitor-treated breast cancer patients with atrophic vaginitis.
- Buchholz S, Mögele M, Lintermans A, Bellen G, Prasauskas V, Ortmann O, Grob P, Neven P, Donders G.
- Climacteric : the journal of the International Menopause Society.Climacteric.2014 Nov 27:1-23. [Epub ahead of print]
- ABSTRACT Objective: We investigated the effect of a combination of vaginal ultra-low-dose estriol with lactobacilli on the sexual functioning domain of quality of life (QOL) during the treatment of breast cancer (BC) survivors on an aromatase inhibitor (AI) with vaginal atrophy. Subjects and Methods
- PMID 25427450
Related Links
- Organon India Ltd. - E-mail/RFQ, Website, Address, Phone, Profile, Directions
- Synonyms: estriol, Oestriol, Estratriol, Tridestrin, Ovestrion, Ovestin, Trihydroxyestrin, Aacifemine, Oestratriol, Oestriolum, Destriol, Overstin, Orestin, Theelol, Thulol, Hemostyptanon, Ortho-Gynest, Orgastyptin, Stiptanon C 18 H ...
★リンクテーブル★
[★]
- 英
- estriol, E3, ET
- ラ
- oestriolum
- 商
- エストリール、ホーリン、メリストラーク
- 関
- 生殖器官用剤
概念
- 女性で産生されるホルモン
- 子宮内膜に対する作用はほとんど無く、主に腟上皮や頚管に作用することから、膣炎、子宮頚管炎、および子宮膣部びらんの治療に用いられる。(参考1 QB.Q-229)
妊娠中の検査としての意義
- NGY.111
- 最近は胎児胎盤機能検査としては使われなくなっている(代わりにNST,BPS,超音波ドプラ、CSTを使用)
- 胎児内分泌機能、胎盤機能、母体-胎盤-胎児血液循環能
尿中エストリオール
。妊娠末期に向かって増加していくが、低値で胎児・胎盤系の機能不全が示唆される。 → 潜在性胎児仮死
- 解釈：(妊娠末期)正常:40mg/day, 注意:≦20mg/day, 危険≦10mg/day
- ex. 082A044
高値
低値
- 胞状奇胎、無脳児妊娠、子宮内胎児死亡、胎児赤芽球症、子宮内胎児発育遅延、胎児胎盤機能不全、胎盤サルファターゼ欠損症、胎盤アロマターゼ欠損症、重症妊娠高血圧症候群
産生
適応
- ホーリンＶ腟用錠1mg
腟炎(老人，小児及び非特異性)，子宮頸管炎並びに子宮腟部びらん
参考
- http://www.info.pmda.go.jp/go/pack/2529701H2046_1_04/2529701H2046_1_04