WordNet
- of first rank or importance or value; direct and immediate rather than secondary; "primary goals"; "a primary effect"; "primary sources"; "a primary interest"
- a preliminary election where delegates or nominees are chosen (同)primary_election
- one of the main flight feathers projecting along the outer edge of a birds wing (同)primary feather, primary quill
- (astronomy) a celestial body (especially a star) relative to other objects in orbit around it
- not derived from or reducible to something else; basic; "a primary instinct"
- having or involving or consisting of more than one part or entity or individual; "multiple birth"; "multiple ownership"; "made multiple copies of the speech"; "his multiple achievements in public life"; "her multiple personalities"; "a pineapple is a multiple fruit"
- the product of a quantity by an integer; "36 is a multiple of 9"
PrepTutorEJDIC
- 『第一の』,『主要な』 / 『初期の』,『初等の』,初級の / 『根本的な』,基本的な,本来の,直接的な / 《名詞の前にのみ用いて》(回路・コイル・巻き・電流などが)一次の / 原色(三原色の一つ) / 《米》=primary election
- 多数の部分(要素)から成る,複合の,複式の / 倍数
- (体内にできる)新生物;腫瘍(しゅよう)
UpToDate Contents
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- 1. 成人における進行性多発性硬化症の治療 treatment of progressive multiple sclerosis in adults
- 2. 多発性硬化症の病態および疫学 pathogenesis and epidemiology of multiple sclerosis
- 3. 多発性硬化症の臨床経過および分類 clinical course and classification of multiple sclerosis
- 4. 多発性骨髄腫における病期分類および予後研究 staging and prognostic studies in multiple myeloma
- 5. 多発性骨髄腫の臨床的特徴、検査所見、および診断 clinical features laboratory manifestations and diagnosis of multiple myeloma
English Journal
- Immunological challenges for peptide-based immunotherapy in glioblastoma.
- Mohme M, Neidert MC, Regli L, Weller M, Martin R.Author information Department of Neurosurgery, University Hospital Zurich, 8091 Zurich, Switzerland; Center for Molecular Neurobiology Hamburg, University Medical Center Eppendorf, 20251 Hamburg, Germany. Electronic address: malte.mohme@zmnh.uni-hamburg.de.AbstractGlioblastoma is the most aggressive primary tumor of the central nervous system with a medium overall survival of 7-15 months after diagnosis. Since tumor cells penetrate the surrounding brain tissue, complete surgical resection is impossible and tumor recurrence is almost a certainty. New treatment modalities are therefore needed, and these should be able to trace, identify, and kill dispersed tumor cells with great accuracy. Immunological approaches in principle meet these needs. Unfortunately, due to profound tumor-associated mechanisms of immunosuppression and -evasion, immunotherapeutic strategies like peptide vaccination have so far not been translated into clinical success. If future, peptide-based vaccination approaches shall be successful in glioblastoma therapy, multiple questions need to be solved including identification of suitable antigens, route and mode of vaccination, preparation of the tumor-bearing "host" and antagonizing, as much as this is possible, glioblastoma-associated mechanisms of immune evasion and poor vaccination response. In this review we will address the immunological challenges of glioblastoma and discuss key aspects that have rendered successful immunotherapy difficult in the past.
- Cancer treatment reviews.Cancer Treat Rev.2014 Mar;40(2):248-58. doi: 10.1016/j.ctrv.2013.08.008. Epub 2013 Sep 8.
- Glioblastoma is the most aggressive primary tumor of the central nervous system with a medium overall survival of 7-15 months after diagnosis. Since tumor cells penetrate the surrounding brain tissue, complete surgical resection is impossible and tumor recurrence is almost a certainty. New treatment
- PMID 24064197
- Sex disparities in diagnosis of bladder cancer after initial presentation with hematuria: A nationwide claims-based investigation.
- Cohn JA, Vekhter B, Lyttle C, Steinberg GD, Large MC.Author information Department of Surgery, Section of Urology, University of Chicago Hospitals, Chicago, Illinois.AbstractBACKGROUND: Women have disproportionately higher mortality rates relative to incidence for bladder cancer. Multiple etiologies have been proposed, including delayed diagnosis and treatment. Guidelines recommend ruling out malignancy in men and women presenting with hematuria. This study sought to determine the difference in timing from presentation with hematuria to diagnosis of bladder cancer in women versus men.
- Cancer.Cancer.2014 Feb 15;120(4):555-61. doi: 10.1002/cncr.28416. Epub 2013 Nov 13.
- BACKGROUND: Women have disproportionately higher mortality rates relative to incidence for bladder cancer. Multiple etiologies have been proposed, including delayed diagnosis and treatment. Guidelines recommend ruling out malignancy in men and women presenting with hematuria. This study sought to de
- PMID 24496869
- Carney complex presenting with a unilateral adrenocortical nodule: a case report.
- Talaei A, Aminorroaya A, Taheri D, Mahdavi KN.AbstractINTRODUCTION: Carney complex is an autosomal dominant syndrome with multiple neoplasms in different sites, including myxomas, endocrine tumors and lentigines lesions. To the best of our knowledge, this is the first report of Carney complex presenting with a unilateral adrenal adenoma associated with a pituitary incidentaloma.
- Journal of medical case reports.J Med Case Rep.2014 Feb 5;8(1):38. [Epub ahead of print]
- INTRODUCTION: Carney complex is an autosomal dominant syndrome with multiple neoplasms in different sites, including myxomas, endocrine tumors and lentigines lesions. To the best of our knowledge, this is the first report of Carney complex presenting with a unilateral adrenal adenoma associated with
- PMID 24499519
Japanese Journal
- 腹腔内転移で発見された唾液腺基底細胞腺癌の 1 例
- 大塲 加央里,清水 進一,山田 真人,赤澤 康弘,土戸 景子,石原 冬馬,大月 寛郎,小林 寛
- 日本臨床細胞学会雑誌 54(2), 140-145, 2015
- 背景 : 唾液腺基底細胞腺癌は低悪性度腫瘍であり, 遠隔転移は比較的まれと考えられている. 今回肝転移および腹膜播種をきたし, 腹水中に腫瘍細胞が出現した本腫瘍の 1 例を経験したので, その細胞像を報告する. 症例 : 60 歳代, 男性. 画像的に多発肝転移, 腹膜播種による腹水貯留や腸閉塞, 水腎症を認めたが, 原発巣は不明であった. 腹水細胞診および肝生検, 小腸切除が施行された. 腹水細 …
- NAID 130005071165
- 腎細胞癌術後30年目に孤立性膵転移を来したと思われる1例
- 江上 拓哉,三浦 哲史,西岡 泰信,岩村 道憲,鬼塚 幸治,北原 光太郎,中村 賢二,八谷 泰孝,福山 時彦,槇原 康亮
- 日本消化器外科学会雑誌 48(4), 344-349, 2015
- … 症例は30年前に左腎癌に対し左腎摘出術の既往を有する79歳の女性で，腰部脊柱管狭窄による腰痛で受診した際のMRIで膵腫瘍を指摘された．膵腫瘍はsolid pseudopapillary neoplasm（以下，SPNと略記）が疑われ膵体尾部切除術を施行したが，病理組織学的に腎細胞癌の組織像に酷似しており，免疫組織化学的にも腎細胞癌に矛盾しないものであったために腎細胞癌の膵転移と判断した．腎細胞癌の膵転移はまれに見られるが多 …
- NAID 130005065289
- Heat shock protein 90 inhibitor NVP-AUY922 exerts potent activity against adult T-cell leukemia–lymphoma cells
- Taniguchi Hiroaki,Hasegawa Hiroo,Sasaki Daisuke,Ando Koji,Sawayama Yasushi,Imanishi Daisuke,Taguchi Jun,Imaizumi Yoshitaka,Hata Tomoko,Tsukasaki Kunihiro,Uno Naoki,Morinaga Yoshitomo,Yanagihara Katsunori,Miyazaki Yasushi
- Cancer Science 105(12), 1601-1608, 2014-12-01
- … Adult T-cell leukemia-lymphoma (ATL), an aggressive neoplasm etiologically associated with HTLV-1, is a chemoresistant malignancy. … Heat shock protein 90 (HSP90) is involved in folding and functions as a chaperone for multiple client proteins, many of which are important in tumorigenesis. … it also inhibited the growth of primary ATL cells, but not of normal PBMCs. …
- NAID 120005526601
Related Links
- 1. World J Surg Oncol. 2014 Sep 22;12:294. doi: 10.1186/1477-7819-12-294. Multiple primary malignant neoplasms of the glottis, renal pelvis, urinary bladder, oral floor, prostate, and esophagus in a Japanese male patient: a case ...
- 1. Am J Clin Oncol. 2003 Feb;26(1):79-83. Multiple primary malignant neoplasms: case report and a comprehensive review of the literature. Demandante CG(1), Troyer DA, Miles TP. Author information: (1)Medical School ...
Related Pictures
★リンクテーブル★
| リンク元 | 「多発性原発性腫瘍」「synchronous neoplasm」 |
| 関連記事 | 「primary」「neoplasm」「multiple」 |
「多発性原発性腫瘍」
「synchronous neoplasm」
「primary」
- adj.
- 一次の、第一次の、主要な、(化学)第一級の、一級の、初生の、(病名)原発性の、原発の、プライマリーの
「neoplasm」
- n.
「multiple」
- n.
- 倍数
- adj.