WordNet
- move something or somebody around; usually over long distances
- an exchange of molecules (and their kinetic energy and momentum) across the boundary between adjacent layers of a fluid or across cell membranes
- move while supporting, either in a vehicle or in ones hands or on ones body; "You must carry your camping gear"; "carry the suitcases to the car"; "This train is carrying nuclear waste"; "These pipes carry waste water into the river" (同)carry
- transport commercially (同)send, ship
- any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes; "a diet high in protein"
- a thin pliable sheet of material
- a pliable sheet of tissue that covers or lines or connects the organs or cells of animals or plants (同)tissue layer
PrepTutorEJDIC
- (ある場所からある場所へ)…‘を'『輸送する』,運搬する《+名+from+名+to+名》 / 《文》《受動態で》(…で)…‘を'夢中にする,有頂天にする《+名+with+名》 / 〈罪人〉‘を'流刑にする / 〈U〉輸送,運送,輸送(交通)機関(transportation) / 〈C〉(軍隊や軍需品を運ぶ)輸送船,輸送機
- 蛋白(たんばく)質
- (生物の)膜,皮膜
Wikipedia preview
出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/02/24 16:26:08」(JST)
[Wiki en表示]
Mitochondrial membrane transport proteins are proteins which exist in the membranes of mitochondria and which serve to transport[1] molecules and other factors such as ions into or out of the organelles.
Examples[edit]
Examples of mitochondrial transport proteins include the following:
- The mitochondrial permeability transition pore, which opens in response to increased mitochondrial calcium (Ca2+) load and oxidative stress[2]
- The mitochondrial calcium uniporter which transports calcium from the cytosol of the cell into the mitochondrial matrix[2][3]
- The mitochondrial sodium/calcium exchanger, which carries Ca2+ ions out of the matrix in exchange for Na+ ions. These transport proteins serve to maintain the proper electrical and chemical gradients in mitochondria by keeping ions and other factors in the right balance between the inside and outside of mitochondria.
See also[edit]
- Mitochondrial carrier
- Membrane transport protein
References[edit]
- ^ Mitochondrial Membrane Transport Proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ a b Crompton M. 1999. The mitochondrial permeability transition pore and its role in cell death. Biochemical Journal. Volume 341, Pages 233-249. PMID 10393078. Retrieved on January 23, 2007.
- ^ Nicholls DG. 2005. Mitochondria and calcium signaling. Cell Calcium, Volume 38, Issues 3-4, Pages 311-317. PMID 16087232. Retrieved on January 23, 2007.
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Membrane proteins, carrier proteins: membrane transport proteins solute carrier (TC 2A)
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Ion pumps
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| Symporter, Cotransporter |
- Na+/K+,l-
- Na/Pi3
- Na+/Cl-
- Na/glucose
- Na+/I-
- Cl-/K+
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| Antiporter (exchanger) |
- Na+/H+
- Na+/Ca2+
- Na+/(Ca2+-K+) - Cl-/HCO3- (Band 3)
- Cl-formate exchanger
- Cl-oxalate exchanger
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see also solute carrier disorders
B memb: cead, trns (1A, 1C, 1F, 2A, 3A1, 3A2-3, 3D), other
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Mitochondrial proteins
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| Outer membrane |
| fatty acid degradation |
- Carnitine palmitoyltransferase I
- Long-chain-fatty-acid—CoA ligase
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| tryptophan metabolism |
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monoamine neurotransmitter
metabolism |
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| Intermembrane space |
- Adenylate kinase
- Creatine kinase
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| Inner membrane |
| oxidative phosphorylation |
- Coenzyme Q – cytochrome c reductase
- Cytochrome c
- NADH dehydrogenase
- Succinate dehydrogenase
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| pyrimidine metabolism |
- Dihydroorotate dehydrogenase
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| mitochondrial shuttle |
- Malate-aspartate shuttle
- Glycerol phosphate shuttle
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| other |
- Glutamate aspartate transporter
- Glycerol-3-phosphate dehydrogenase
- ATP synthase
- Carnitine palmitoyltransferase II
- Uncoupling protein
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| Matrix |
| citric acid cycle |
- Citrate synthase
- Aconitase
- Isocitrate dehydrogenase
- Oxoglutarate dehydrogenase complex
- Succinyl coenzyme A synthetase
- Fumarase
- Malate dehydrogenase
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| anaplerotic reactions |
- Aspartate transaminase
- Glutamate dehydrogenase
- Pyruvate dehydrogenase complex
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| urea cycle |
- Carbamoyl phosphate synthetase I
- Ornithine transcarbamylase
- N-Acetylglutamate synthase
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| alcohol metabolism |
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| Other/to be sorted |
| steroidogenesis |
- Cholesterol side-chain cleavage enzyme
- Steroid 11-beta-hydroxylase
- Aldosterone synthase
- Frataxin
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- Mitochondrial membrane transport protein
- Mitochondrial permeability transition pore
- Mitochondrial carrier
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| Mitochondrial DNA |
| Complex I |
- MT-ND1
- MT-ND2
- MT-ND3
- MT-ND4
- MT-ND4L
- MT-ND5
- MT-ND6
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| Complex III |
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| Complex IV |
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| ATP synthase |
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| tRNA |
- MT-TA
- MT-TC
- MT-TD
- MT-TE
- MT-TF
- MT-TG
- MT-TH
- MT-TI
- MT-TK
- MT-TL1
- MT-TL2
- MT-TM
- MT-TN
- MT-TP
- MT-TQ
- MT-TR
- MT-TS1
- MT-TS2
- MT-TT
- MT-TV
- MT-TW
- MT-TY
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see also mitochondrial diseases
B strc: edmb (perx), skel (ctrs), epit, cili, mito, nucl (chro)
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UpToDate Contents
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English Journal
- Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cells.
- Lucki NC, Li D, Sewer MB.SourceSchool of Biology, Georgia Institute of Technology, Atlanta, GA 30332-0230, USA.
- Molecular and cellular endocrinology.Mol Cell Endocrinol.2012 Jan 2;348(1):165-75. Epub 2011 Aug 16.
- In the acute phase of adrenocortical steroidogenesis, adrenocorticotrophin (ACTH) activates a cAMP/PKA-signaling pathway that promotes the transport of free cholesterol to the inner mitochondrial membrane. We have previously shown that ACTH rapidly stimulates the metabolism of sphingolipids and the
- PMID 21864647
- The translocator protein (peripheral benzodiazepine receptor) mediates rat-selective activation of the mitochondrial permeability transition by norbormide.
- Zulian A, Sileikytė J, Petronilli V, Bova S, Dabbeni-Sala F, Cargnelli G, Rennison D, Brimble MA, Hopkins B, Bernardi P, Ricchelli F.SourceC.N.R. Institute of Neurosciences at the Department of Biomedical Sciences, University of Padova, Padova, Italy.
- Biochimica et biophysica acta.Biochim Biophys Acta.2011 Dec;1807(12):1600-5. Epub 2011 Aug 26.
- We have investigated the mechanism of rat-selective induction of the mitochondrial permeability transition (PT) by norbormide (NRB). We show that the inducing effect of NRB on the PT (i) is inhibited by the selective ligands of the 18kDa outer membrane (OMM) translocator protein (TSPO, formerly peri
- PMID 21889488
Japanese Journal
- Astaxanthin Induces Mitochondria-Mediated Apoptosis in Rat Hepatocellular Carcinoma CBRH-7919 Cells
- Song Xiao-dong,Zhang Jin-jin,Wang Mei-rong,Liu Wen-bo,Gu Xin-bin,Lv Chang-jun
- Biological & Pharmaceutical Bulletin 34(6), 839-844, 2011
- … Cell apoptosis rate, changes of mitochondrial morphology, mitochondrial transmembrane potential and electron transport chain were evaluated respectively. … Expressions of B cell lymphoma/leukemia-2 (Bcl-2) and Bcl-2 associated X protein (Bax) were detected by Western blot. … Astaxanthin could induce cell apoptosis and mitochondrial membrane damage. …
- NAID 130000738058
- ミトコンドリア内膜のADP/ATP透過担体のC末端領域の構造特性と機能
- 篠原 康雄,橋本 満,木平 孝高,大倉 一人,真島 英司,寺田 弘
- YAKUGAKU ZASSHI 130(2), 199-204, 2010
- … Mitochondrial ADP/ATP carrier (AAC) is a protein catalyzing the transport of adenine nucleotides across inner mitochondrial membrane. … In this review article, we first briefly introduce structural and functional properties of this protein. …
- NAID 130000171288
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- Mitochondrial membrane transport proteins are proteins which exist in the membranes of mitochondria and which serve to transport molecules and other factors such as ions into or out of the organelles. Examples Examples of ...
★リンクテーブル★
[★]
- 英
- mitochondrial membrane transport protein
[★]
- 関
- bring、carriage、carry、convey、delivery、ship、traffic、trafficking、transportation
[★]
- 関
- binding protein、carrier protein、translocator、transporter、transporter protein
[★]
- 関
- inner mitochondrial membrane、outer mitochondrial membrane
[★]
- 関
- mitochondria、mitochondrially、mitochondrion
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