メチラポン試験
WordNet
- undergo a test; "She doesnt test well"
- any standardized procedure for measuring sensitivity or memory or intelligence or aptitude or personality etc; "the test was standardized on a large sample of students" (同)mental test, mental testing, psychometric test
- the act of undergoing testing; "he survived the great test of battle"; "candidates must compete in a trial of skill" (同)trial
- the act of testing something; "in the experimental trials the amount of carbon was measured separately"; "he called each flip of the coin a new trial" (同)trial, run
- a hard outer covering as of some amoebas and sea urchins
- put to the test, as for its quality, or give experimental use to; "This approach has been tried with good results"; "Test this recipe" (同)prove, try, try out, examine, essay
- achieve a certain score or rating on a test; "She tested high on the LSAT and was admitted to all the good law schools"
- determine the presence or properties of (a substance)
- show a certain characteristic when tested; "He tested positive for HIV"
- an examination of the characteristics of something; "there are laboratories for commercial testing"; "it involved testing thousands of children for smallpox"
- the act of subjecting to experimental test in order to determine how well something works; "they agreed to end the testing of atomic weapons"
- tested and proved useful or correct; "a tested method" (同)tried, well-tried
- tested and proved to be reliable (同)time-tested, tried, tried and true
PrepTutorEJDIC
- (人の能力などの)『試験』,考査,テスト / (物事の)『試験』,検済,試錬,実験《+of+名》 / 化学分析;試薬 / =test match / …‘を'『試験する』,検査する / …‘を'化学分析する / (…の)試験を受ける,試験をする《+for+名》
- testis の複数形
UpToDate Contents
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English Journal
- Antidepressant augmentation with metyrapone for treatment-resistant depression (the ADD study): a double-blind, randomised, placebo-controlled trial.
- McAllister-Williams RH1, Anderson IM2, Finkelmeyer A3, Gallagher P4, Grunze HC5, Haddad PM6, Hughes T7, Lloyd AJ3, Mamasoula C8, McColl E8, Pearce S9, Siddiqi N10, Sinha BN11, Steen N8, Wainwright J4, Winter FH4, Ferrier IN3, Watson S3; ADD Study Team.
- The lancet. Psychiatry.Lancet Psychiatry.2016 Feb;3(2):117-27. doi: 10.1016/S2215-0366(15)00436-8. Epub 2015 Dec 23.
- BACKGROUND: Many patients with major depressive disorder have treatment-resistant depression, defined as no adequate response to two consecutive courses of antidepressants. Some evidence suggests that antiglucocorticoid augmentation of antidepressants might be efficacious in patients with major depr
- PMID 26727041
- Effects of the pattern of glucocorticoid replacement on neural processing, emotional reactivity and well-being in healthy male individuals: study protocol for a randomised controlled trial.
- Kalafatakis K1,2,3, Russell GM4,5, Harmer CJ6, Munafo MR7, Marchant N8,9, Wilson A10, Brooks JC11, Thai NJ12, Ferguson SG13, Stevenson K14, Durant C15, Schmidt K16, Lightman SL17,18.
- Trials.Trials.2016 Jan 22;17(1):44. doi: 10.1186/s13063-016-1159-x.
- BACKGROUND: Deviation from the physiological glucocorticoid dynamics (circadian and underlying ultradian rhythmicity) is a common characteristic of various neuropsychiatric and endocrine disorders as well as glucocorticoid-based therapeutics. These states may be accompanied by neuropsychiatric sympt
- PMID 26801980
- Behavioral and Biochemical Interaction Between Nicotine and Chronic Unpredictable Mild Stress in Mice.
- Biala G1, Pekala K2, Boguszewska-Czubara A3, Michalak A2, Kruk-Slomka M2, Budzynska B2.
- Molecular neurobiology.Mol Neurobiol.2016 Jan 18. [Epub ahead of print]
- Nicotine, the main component of tobacco smoke, exerts influence on mood, and contributes to physical and psychological dependence. Taking into account frequent concomitance of nicotine abuse and stress, we aimed to research behavioral and biochemical effects associated with nicotine administration i
- PMID 26780460
Japanese Journal
- Clinical features and management of ectopic ACTH syndrome at a single institute in Japan
- DOI Masaru,SUGIYAMA Toru,IZUMIYAMA Hajime,YOSHIMOTO Takanobu,HIRATA Yukio
- Endocrine journal 57(12), 1061-1069, 2010-12-01
- NAID 10029587142
- Clinical features and management of ectopic ACTH syndrome at a single institute in Japan
- Doi Masaru,Sugiyama Toru,Izumiyama Hajime,Yoshimoto Takanobu,Hirata Yukio
- Endocrine Journal 57(12), 1061-1069, 2010
- … Dynamic endocrine tests revealed markedly elevated plasma ACTH levels (211 ± 116pg/mL) and cortisol levels (60.9 ± 30.1μg/dL) which showed resistance to overnight high-dose (8mg) dexamethasone suppression test in 15 (94%) and unresponsiveness to CRH stimulation in 12 (75%). … Six occult/unknown EAS patients survived for 67.5 months after medical treatment with metyrapone to control hypercortisolism. …
- NAID 130004443603
- 鶴岡 浩志
- 動物臨床医学 13(3/4), 111-113, 2004
- 10歳齢の雑種猫が全身の脱毛および元気,食欲の低下を主訴として来院した。全身徴候としては,削痩,腹囲膨大,腹部皮膚の菲薄化が認められ,問診によると数日前までは多飲,多尿,多食であることも明らかになった。血液検査,低用量デキサメサゾン抑制試験の結果,さらに,ステロイド剤の投与歴がないことから自然発生副腎皮質機能亢進症と診断した。メチラポンの投与により元気,食欲はやや改善されたが,尿糖は改善されず,1 …
- NAID 130004935121
Related Links
- Metyrapone test may aid in verifying the cause of Cushing's syndrome. Most patients with pituitary dysfunction and/or pituitary microadenoma will increase ACTH secretion in response to metyrapone, while most ectopic ACTH-producing ...
- 3 Oct 2012 ... Thestimulation test is based upon the principle that decreasing serum cortisol concentrations is expected to produce an increase in corticotropin (ACTH) secretion. The utilization of the metyrapone test has become less ...
Related Pictures
★リンクテーブル★
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- 英
- metyrapone test
- 同
- メトピロン試験 メトピロン負荷試験 metopirone test、メチラポン負荷試験、メチラポン負荷テスト
- 関
- メチラポン、糖質コルチコイド、クッシング症候群
[show details]
- 下垂体-副腎皮質系の予備能を検索する。クッシング症候群の鑑別を目的に行われる。クッシング病では正常~過大反応(代償的)。
- メチラポンを投与すると11β-hydroxylase阻害作用によりコルチゾール産生減少 → ネガティブフィードバック機構によりATCH産生亢進 → 11-deoxycortisol産生↑、あるいはこの代謝産物であるtetrahydrodeoxycortisol(THS)↑を17-OHCS これを尿中排泄を見る
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- 関
- assessment、data quality、exam、examination、examine、experimental design、matched group、measurement、research design、scoring method、test、trial
[★]
テスト
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メチラポン
-metyrapone