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出典(authority):フリー百科事典『ウィキペディア(Wikipedia)』「2015/07/21 16:55:13」(JST)
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Megamitochondria is extremely large and abnormal shapes of mitochondria seen in hepatocytes in alcoholic liver disease and in nutritional deficiencies. It can be seen in conditions of hypertrophy in cell death.
References
- Robbins Basic Pathology by Kumer et al.[page needed]
Medicine: Pathology
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Principles of pathology |
- Disease
- Infection
- Neoplasia
- Etiology
- Pathogenesis
- Hemodynamics
- Inflammation
- Cell damage
- Wound healing
- Cellular adaptation
- Atrophy
- Hypertrophy
- Hyperplasia
- Dysplasia
- Metaplasia
- Squamous
- Glandular
- Cell death
- Necrosis
- Liquefactive necrosis
- Coagulative necrosis
- Caseous necrosis
- Fat necrosis
- Programmed cell death
- Apoptosis
- Pyknosis
- Karyorrhexis
- Karyolysis
- Accumulations:
- pigment
- Hemosiderin
- Lipochrome/Lipofuscin
- Melanin
- Steatosis
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Anatomical pathology |
- Surgical pathology
- Cytopathology
- Autopsy
- Molecular pathology
- Forensic pathology
- Oral and maxillofacial pathology
- Gross examination
- Histopathology
- Immunohistochemistry
- Electron microscopy
- Immunofluorescence
- Fluorescence in situ hybridization
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Clinical pathology |
- Clinical chemistry
- Hematopathology
- Transfusion medicine
- Medical microbiology
- Diagnostic immunology
- Immunopathology
- Enzyme assay
- Mass spectrometry
- Chromatography
- Flow cytometry
- Blood bank
- Microbiological culture
- Serology
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Specific conditions |
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UpToDate Contents
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English Journal
- Alcoholic and non-alcoholic steatohepatitis.
- Neuman MG1, French SW2, French BA2, Seitz HK3, Cohen LB4, Mueller S3, Osna NA5, Kharbanda KK5, Seth D6, Bautista A7, Thompson KJ8, McKillop IH8, Kirpich IA9, McClain CJ10, Bataller R11, Nanau RM12, Voiculescu M13, Opris M14, Shen H2, Tillman B2, Li J2, Liu H2, Thomes PG5, Ganesan M5, Malnick S15.
- Experimental and molecular pathology.Exp Mol Pathol.2014 Dec;97(3):492-510. doi: 10.1016/j.yexmp.2014.09.005. Epub 2014 Sep 11.
- This paper is based upon the "Charles Lieber Satellite Symposia" organized by Manuela G. Neuman at the Research Society on Alcoholism (RSA) Annual Meetings, 2013 and 2014. The present review includes pre-clinical, translational and clinical research that characterize alcoholic liver disease (ALD) an
- PMID 25217800
- Methylmalonic acidemia: a megamitochondrial disorder affecting the kidney.
- Zsengellér ZK1, Aljinovic N, Teot LA, Korson M, Rodig N, Sloan JL, Venditti CP, Berry GT, Rosen S.
- Pediatric nephrology (Berlin, Germany).Pediatr Nephrol.2014 Nov;29(11):2139-46. doi: 10.1007/s00467-014-2847-y. Epub 2014 May 28.
- BACKGROUND: Classical (or isolated) methylmalonic acidemia (MMA) is a heterogeneous inborn error of metabolism most typically caused by mutations in the vitamin B12-dependent enzyme methylmalonyl-CoA mutase (MUT). With the improved survival of individuals with MMA, chronic kidney disease has become
- PMID 24865477
Japanese Journal
- The zonal distribution of megamitochondria with crystalline inclusions in nonalcoholic steatohepatitis
- Starvation induces the formation of giant mitochondria in gastric parietal cells of guinea pigs
- OGAWA Kazushige,NOGUCHI Hiroyo,TSUJI Masashi,SASAKI Fumihiko
- Journal of electron microscopy 52(2), 217-225, 2003-04-01
- NAID 50000257263
Related Links
- megamitochondria Massively enlarged mitochondria, which are typically seen in alcoholic livers but are also seen in malnutrition, in skeletal muscle with myopathy and in cancer. Megamitochondria (MG) formation is attributed to free ...
- Correlation between chloramphenicol-induced formation of megamitochondria in the mouse liver and oxidative stress was studied by lipid peroxidation analysis and ... Mechanism of the formation of megamitochondria in the mouse ...
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- 関
- 肝臓、肝炎
病変局在と疾患
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