WordNet
- small room in which a monk or nun lives (同)cubicle
- a device that delivers an electric current as the result of a chemical reaction (同)electric cell
- a room where a prisoner is kept (同)jail cell, prison cell
- (biology) the basic structural and functional unit of all organisms; they may exist as independent units of life (as in monads) or may form colonies or tissues as in higher plants and animals
- any small compartment; "the cells of a honeycomb"
- a small unit serving as part of or as the nucleus of a larger political movement (同)cadre
- spread over a surface, like a mantle
- (zoology) a protective layer of epidermis in mollusks or brachiopods that secretes a substance forming the shell (同)pallium
- the cloak as a symbol of authority; "place the mantle of authority on younger shoulders"
- the layer of the earth between the crust and the core
- cover like a mantle; "The ivy mantles the building"
- a neoplasm of lymph tissue that is usually malignant; one of the four major types of cancer
- United States baseball player (1931-1997) (同)Mickey Mantle, Mickey Charles Mantle
PrepTutorEJDIC
- (刑務所の)『独房』;(修道院の)小さい独居室 / (ミツバチの)みつ房,巣穴 / 小さい部屋 / 『細胞』 / 電池 / 花粉室 / (共産党などの)細胞
- 《古》(ゆったりしたそでのない)外とう,マント / 覆うもの,包み隠すもの / (ガス灯の)マントル / マントル,外とう部(地球内部の地殻と核との間の部分) / =mantelpiece / …‘を'マントで覆う;《文》(マントで覆うように)…‘を'覆う,包む,隠す
UpToDate Contents
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- 1. マントル細胞リンパ腫の臨床症状、病理学的特徴、および診断 clinical manifestations pathologic features and diagnosis of mantle cell lymphoma
- 2. マントル細胞リンパ腫の初期治療 initial treatment of mantle cell lymphoma
- 3. 再発性または難治性のマントル細胞リンパ腫の治療 treatment of relapsed or refractory mantle cell lymphoma
- 4. マントル細胞リンパ腫の病理学 pathobiology of mantle cell lymphoma
- 5. 自家造血幹細胞移植の適格性判定 determining eligibility for autologous hematopoietic cell transplantation
English Journal
- Candidate genes contributing to the aggressive phenotype of mantle cell lymphoma.
- Henson SE, Morford T, Stein MP, Wall R, Malone CS.SourceDepartment of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA 90095, USA.
- Acta histochemica.Acta Histochem.2011 Nov;113(7):729-42. Epub 2010 Dec 9.
- Mantle cell lymphoma and small lymphocytic lymphoma are lymphocyte cancers that have similar morphologies and a common age of onset. Mantle cell lymphoma is generally an aggressive B cell lymphoma with a short median survival time, whereas small lymphocytic lymphoma is typically an indolent B cell l
- PMID 21145576
- Biodistribution, Pharmacokinetics, and Nuclear Imaging Studies of (111)In-labeled rGel/BLyS Fusion Toxin in SCID Mice Bearing B Cell Lymphoma.
- Wen X, Lyu MA, Zhang R, Lu W, Huang Q, Liang D, Rosenblum MG, Li C.SourceDepartment of Experimental Diagnostic Imaging, Unit 59, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA.
- Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging.Mol Imaging Biol.2011 Aug;13(4):721-9.
- PURPOSE: We examined the biodistribution and pharmacokinetics of (111)In-labeled rGel/BLyS, a gelonin toxin (rGel)-B lymphocyte stimulator (BLyS) fusion protein.MATERIALS AND METHODS: rGel/BLyS was labeled with In-111 through DTPA with a labeling efficiency >95%. Biodistribution/imaging studies w
- PMID 20686856
Japanese Journal
- CD5-Positive Follicular Lymphoma: A Case Report and Literature Review
- Sekiguchi Yasunobu,Imai Hidenori,Wakabayashi Mutsumi,Sawada Tomohiro,Ichikawa Kunimoto,Komatsu Norio,Noguchi Masaaki
- Internal Medicine 50(8), 899-904, 2011
- … A pathological diagnosis of follicular lymphoma (FL), grade 3A, was made based on a biopsy specimen from the right inguinal lymph node. … The immunophenotypes of the lymphoma cells were CD3-, CD5+, CD7-, CD10+, CD19+, CD20+, CD23+, IgM+, Igκ-, and Igλ+. … Fluorescence-activated cell sorting (FACS) dual staining indicated that the cells were double-positive for both CD5 and CD20. …
- NAID 130000650081
- Current treatment strategy and new agents in mantle cell lymphoma
- OGURA Michinori
- International journal of hematology 92(1), 25-32, 2010-07-15
- NAID 10026511728
Related Links
- ヘアリーセル白血病 Hairly cell leukemia; 濾胞性リンパ腫 Follicular center lymphoma; マントル細胞リンパ腫 Mantle cell ... 前駆T細胞リンパ芽球性リンパ腫/ 白血病 Precursor T cell lymphoblastic lymphoma/leukemia (T-LBL); 慢性Tリンパ球性 ...
Related Pictures
★リンクテーブル★
| リンク元 | 「マントル細胞リンパ腫」「外套層状リンパ腫」「暗殻細胞リンパ腫」「intermediate lymphocytic lymphoma」 |
| 関連記事 | 「mantle」「cell」 |
「マントル細胞リンパ腫」
- 英
- mantle-cell lymphoma, mantle cell lymphoma
- 関
- 暗殻細胞リンパ腫、中間型リンパ球性リンパ腫 intermediate lymphocytic lymphoma、外套層状リンパ腫 mantle zone lymphoma
- 悪性リンパ腫
概念
- 成熟B細胞腫瘍の一種
- 染色体転座t(11;14)(q13;q32)が認められる。
- CD5を発現する。CyclinD1遺伝子の過剰発現は高頻度
- 別名：MCL has been previously referred to as intermediate lymphocytic lymphoma, mantle zone lymphoma, centrocytic lymphoma, and lymphocytic lymphoma of intermediate differentiation
発生母地
- Most MCL cases are postulated to derive from naïve pre-germinal center B cells of the mantle zone, while a subset of MCL may originate from marginal zone or peripheral blood memory B cells.
講義ノート
- 中リンパ球
- 核クロマチンは均一に濃縮し、核小体は不明瞭。核は軽度の不整とくびれ有り(convoluted cell)
- マントル細胞リンパ腫は慢性リンパ性白血病と同様にCD5(+)のB細胞であるが、予後は大きく異なり、化学療法のCHOPが奏効しにくく、寛解率は10-40%。
細胞表面マーカー
| sIg | ＋ | 細胞表面のIg |
| CD5 | ＋ | 胸腺細胞、T細胞、B細胞のサブセット |
| CD10 | － | B細胞やT細胞前駆体。骨髄間質細胞(bone marrow stromal cell) 。Zinc metalloproteinase, marker for pre-B acute lymphatic leukemia (ALL) |
| CD19 | ＋ | B-cell co-receptor: CD19+CD21+CD81 |
| cyclin | ＋ | サイクリン依存性キナーゼ(CDK)の活性化サブユニット |
| *Bリンパ球のマーカーとされているもの CD10,CD19,CD20 | ||
発生母地
- The malignant cell in mantle cell lymphoma is postulated to derive from a naive B-cell of follicle mantle or germinal center origin. This cell is distinct from both the recirculating B-cell of B-CLL/SLL and the later centrocyte of follicular lymphoma
-mantle-cell lymphoma
「外套層状リンパ腫」
「暗殻細胞リンパ腫」
「intermediate lymphocytic lymphoma」
「mantle」
- n.