WordNet

pursue a positive and satisfying existence; "You must accept yourself and others if you really want to live"
actually being performed at the time of hearing or viewing; "a live television program"; "brought to you live from Lincoln Center"; "live entertainment involves performers actually in the physical presence of a live audience" (同)unrecorded
abounding with life and energy; "the club members are a really live bunch"
charged with an explosive; "live ammunition"; "a live bomb"
exerting force or containing energy; "live coals"; "tossed a live cigarette out the window"; "got a shock from a live wire"; "live ore is unmined ore"; "a live bomb"; "a live ball is one in play"
highly reverberant; "a live concert hall"
in current use or ready for use; "live copy is ready to be set in type or already set but not yet proofread"
lead a certain kind of life; live in a certain style; "we had to live frugally after the war"
not recorded; "the opera was broadcast live"
of current relevance; "a live issue"; "still a live option"
any physical damage to the body caused by violence or accident or fracture etc. (同)hurt, harm, trauma
an act that causes someone or something to receive physical damage
wrongdoing that violates anothers rights and is unjustly inflicted
an accident that results in physical damage or hurt (同)accidental injury
a person who has a special life style; "a high liver"
large and complicated reddish-brown glandular organ located in the upper right portion of the abdominal cavity; secretes bile and functions in metabolism of protein and carbohydrate and fat; synthesizes substances involved in the clotting of the blood; sy
liver of an animal used as meat
someone who lives in a place; "a liver in cities"

PrepTutorEJDIC

『生きている』,生命がある / 《副詞[句]を伴って》〈人などが〉『生き続ける』 / 〈物事が〉長く続く,存続する / 《場所を表す副詞[句]を伴って》〈人などが〉『住む』,居住する / 《副詞[句]を伴って》『生活する』,暮らす / 生人を楽しむ,おもしろく桟らす / 《a+形容詞癌lifeを目的語にして》〈…を生活〉‘を'する / 〈思想など〉‘を'実銭する
《名詞の前にのみ用いて》『生きている』 / 『活気のある』 / (問題などが)当面の / 燃えている / (弾丸などが)まだ爆発してない,未発の / まだ動いている(働いている),有効な / 電流が通じている / (放走が)生の,実況の
『負傷』,『損害』,損傷 / (名誉などを)傷つけること,侮辱《+『to』+『名』》
(ある態度で)生活する人;居住者
〈C〉『肝臓』 / 〈U〉(食用にする)動物の肝臓,レバー

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/07/09 20:27:10」(JST)

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A liver injury is some form of trauma sustained to the liver. This can occur through either a blunt force such as a car accident, or a penetrating foreign object such as a knife.^[1] Liver injuries constitute 5% of all traumas, making it the most common abdominal injury.^[2] Generally nonoperative management and observation is all that is required for a full recovery.

Cause[edit]

Given its anterior position in the body and its large shape, is it prone to gun shot wounds and stab wounds.^[2] Its firm location under the diaphragm also makes it especially prone to shearing forces.^[1] Common causes of this type of injury are blunt force mechanisms such as motor vehicle accidents, falls, and sports injuries. Typically these blunt forces dissipate through and around the structure of the liver.^[3] A large majority of people who sustain this injury also have another accompanying injury.^[1]

Diagnosis[edit]

Imaging, such as the use of ultrasound or a computed tomography scan, is the generally preferred way of diagnosis as it is more accurate and is sensitive to bleeding, however; due to logistics this is not always possible.^[4] For a person who is hemodynamically unstable a focused assessment with sonography for trauma (FAST) scan may take place which is used to find free floating fluid in the right upper quadrant and left lower quadrant of the abdomen. A physical examination may be used but is typically inaccurate in blunt trauma, unlike in penetrating trauma where the trajectory the projectile took can be followed digitally.^[5] A diagnostic peritoneal lavage may also be utilized but has limited application as it is hard to determine the origin of the bleeding.^[6]

Classification[edit]

**The Liver Injury Scale classification**^[1]^[2]
Grade	Subcapsular hematoma	Laceration
I	<10% surface area	< 1 cm in depth
II	10–50% surface area	1–3 cm
III	>50% or >10 cm	>3 cm
IV	25–75% of a hepatic lobe
V	>75% of a hepatic lobe
VI	Hepatic avulsion

Liver injuries are classified on a roman numeral scale with I being the lease severe, to VI being the most severe. Generally any injury ≥III requires surgery.^[3]^[7]

Management[edit]

The initial management of liver trauma generally follows the same procedures for all traumas with a focus on maintaining airway, breathing, and circulation. A physical examination is a corner stone of the assessment of which there are various non-invasive means of diagnostic tools that can be utilized.^[3] An invasive diagnostic peritoneal lavage can also be used to diagnose and classify the extent of the damage.^[8]^[9] A large majority of liver injuries are minor and require only observation.^[10] Generally if there is estimated to be less than 300mL of free floating fluid, no injury to surrounding organs, and no need for blood transfusion, there is a low risk of complication from nonoperative management.^[1] In special cases where there is a higher risk with surgery, such as in the elderly, nonoperative management would include the infusion of packed red blood cells in an intensive care unit.^[2] Typically hepatic injuries resulting from stab wounds cause little damage unless a vital part of the liver is injured such as the hepatic portal vein, with gunshot wounds, the damage is worse.^[11]

Surgery[edit]

In severe liver injuries (class ≥III), surgical correction is generally necessary. In these severe injuries a hepatopancreatobiliary surgeon may be utilized rather than a trauma surgeon given their expertise with the organ and generally yields better outcomes.^[1] Surgical techniques such as perihepatic packing or the use of the Pringle manoeuvre can be used to control hemorrhage.^[2]^[3] Temporary control of the hemorrhage can be direct manual pressure to the wound site.^[2] In these severe cases it is important to prevent the progression of the trauma triad of death, which often requires the utilization of damage control surgery.^[9] The common cause of death while operating is exsanguination caused by profuse loss of blood volume.^[12] Rarely, surgery entails the use of liver resection, which removes the source of the bleeding and necrotic tissue. The drastic nature of this procedure means it can only be used in hemodynamically stable patients.^[7] Another rare procedure would be liver transplantation which is typically impractical due to the logistics of finding a proper organ donor in a timely fashion.^[13]

History[edit]

In the 1880s a severe liver injury would in most cases prove fatal in the first 24 hours after sustaining the injury.^[14] Before the 1980s nonoperative management was seldom used in favor of the methods of management suggested by James Hogarth Pringle.^[15]^[16] During World War II the use of early laparotomy was popularized and in conjunction with the use of transfusions, advanced anesthetics, and other new surgical techniques led to decreased mortality.^[17]

References[edit]

^ ^a ^b ^c ^d ^e ^f Piper GL, Peitzman AB (August 2010). "Current management of hepatic trauma". The Surgical Clinics of North America 90 (4): 775–85. doi:10.1016/j.suc.2010.04.009. PMID 20637947. Retrieved 2012-08-03.
^ ^a ^b ^c ^d ^e ^f Cothren, C. C.; Moore, E. E. (2008). "Hepatic Trauma". European Journal of Trauma and Emergency Surgery 34 (4): 339. doi:10.1007/s00068-008-8029-5. edit
^ ^a ^b ^c ^d Bouras AF, Truant S, Pruvot FR (December 2010). "Management of blunt hepatic trauma". Journal of Visceral Surgery 147 (6): e351–8. doi:10.1016/j.jviscsurg.2010.10.004. PMID 21111696. Retrieved 2012-08-03.
^ Moore 2012, p. 543
^ Pietzman 2002, p. 255
^ Moore 2012, p. 542
^ ^a ^b Arkuszewski, P.; Krawczyk, M. (2009). "Surgical Management of Liver Trauma". Polish Journal of Surgery 81 (11): 554. doi:10.2478/v10035-009-0090-1. edit
^ Moore 2012, p. 541
^ ^a ^b Stracieri LD, Scarpelini S (2006). "Hepatic injury". Acta Cirúrgica Brasileira / Sociedade Brasileira Para Desenvolvimento Pesquisa Em Cirurgia. 21 Suppl 1: 85–8. PMID 17013521. Retrieved 2012-07-28.
^ American College of Surgeons (2004). Atls, Advanced Trauma Life Support Program for Doctors. Amer College of Surgeons. ISBN 1-880696-14-2.
^ Kenneth D. Boffard (2007). Manual of definitive surgical trauma care. London: Hodder Arnold. p. 108. ISBN 0-340-94764-0.
^ Ahmed, I.; Beckingham, I. (2007). "Liver trauma". Trauma 9 (3): 171. doi:10.1177/1460408607086775. edit
^ Parks RW, Chrysos E, Diamond T (September 1999). "Management of liver trauma". The British Journal of Surgery 86 (9): 1121–35. doi:10.1046/j.1365-2168.1999.01210.x. PMID 10504364. Retrieved 2012-08-04.
^ Moynihan, Baron Berkeley (1906). Abdominal operations. Saunders. p. 563. Retrieved 2012-08-04.
^ Pringle JH (October 1908). "V. Notes on the Arrest of Hepatic Hemorrhage Due to Trauma". Annals of Surgery 48 (4): 541–9. PMC 1406963. PMID 17862242. Retrieved 2012-08-03.
^ Feliciano DV, Rozycki GS (2002). "Hepatic trauma". Scandinavian Journal of Surgery : SJS : Official Organ for the Finnish Surgical Society and the Scandinavian Surgical Society 91 (1): 72–9. PMID 12075841. Retrieved 2012-08-03.
^ Moore 2012, p. 539

Bibliography[edit]

Feliciano, David V.; Mattox, Kenneth L.; Moore, Ernest J (2012). Trauma, Seventh Edition (Trauma (Moore)). McGraw-Hill Professional. ISBN 0-07-166351-7.
Andrew B., MD Peitzman; Andrew B. Peitzman; Michael, MD Sabom; Donald M., MD Yearly; Timothy C., MD Fabian (2002). The trauma manual. Hagerstwon, MD: Lippincott Williams & Wilkins. ISBN 0-7817-2641-7.

UpToDate Contents

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1. 成人における肝外傷のマネージメント management of hepatic trauma in adults
2. 肝酵素および肝機能検査値の異常が認められた患者に対するアプローチ approach to the patient with abnormal liver biochemical and function tests
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5. 肝障害のマネージメントのための外科手技 surgical techniques for managing hepatic injury

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★リンクテーブル★

リンク元	「肝損傷」「肝傷害」「hepatic injury」
拡張検索	「alcoholic liver injury」「allergic liver injury」
関連記事	「injury」「live」「liver」