WordNet
- a cellular structure that is postulated to exist in order to mediate between a chemical agent that acts on nervous tissue and the physiological response
PrepTutorEJDIC
- =sense organ / 受信装置
UpToDate Contents
全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.
- 1. 血液透析装置の概要 overview of the hemodialysis apparatus
- 2. 成人におけるセリアック病の病因、疫学、および臨床症状 pathogenesis epidemiology and clinical manifestations of celiac disease in adults
- 3. 成人における発熱の病態生理および治療 pathophysiology and treatment of fever in adults
- 4. 嫌気性感染症における病態生理、臨床的な手がかり、および微生物の回収方法 pathophysiology clinical clues and recovery of organisms in anaerobic infections
- 5. 敗血症に対する治験剤および無効剤 investigational and ineffective therapies for sepsis
English Journal
- Pathogen-associated molecular patterns activate expression of genes involved in cell proliferation, immunity and detoxification in the amebocyte-producing organ of the snail Biomphalaria glabrata.
- Zhang SM1, Loker ES2, Sullivan JT3.
- Developmental and comparative immunology.Dev Comp Immunol.2016 Mar;56:25-36. doi: 10.1016/j.dci.2015.11.008. Epub 2015 Nov 22.
- The anterior pericardial wall of the snail Biomphalaria glabrata has been identified as a site of hemocyte production, hence has been named the amebocyte-producing organ (APO). A number of studies have shown that exogenous abiotic and biotic substances, including pathogen associated molecular patter
- PMID 26592964
- Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection.
- Carey AJ1, Sullivan MJ1, Duell BL1, Crossman DK2, Chattopadhyay D3, Brooks AJ4, Tan CK1, Crowley M2, Sweet MJ5, Schembri MA6, Ulett GC7.
- The Journal of infectious diseases.J Infect Dis.2016 Feb 15;213(4):659-68. doi: 10.1093/infdis/jiv424. Epub 2015 Aug 30.
- BACKGROUND: CD14, a coreceptor for several pattern recognition receptors and a widely used monocyte/macrophage marker, plays a key role in host responses to gram-negative bacteria. Despite the central role of CD14 in the inflammatory response to lipopolysaccharide and other microbial products and in
- PMID 26324782
- Inflammation Increases Neuronal Sensitivity to General Anesthetics.
- Avramescu S1, Wang DS, Lecker I, To WT, Penna A, Whissell PD, Mesbah-Oskui L, Horner RL, Orser BA.
- Anesthesiology.Anesthesiology.2016 Feb;124(2):417-27. doi: 10.1097/ALN.0000000000000943.
- BACKGROUND: Critically ill patients with severe inflammation often exhibit heightened sensitivity to general anesthetics; however, the underlying mechanisms remain poorly understood. Inflammation increases the number of γ-aminobutyric acid type A (GABAA) receptors expressed on the surface of neuron
- PMID 26566283
Japanese Journal
- Landiolol hydrochloride ameliorates acute lung injury in a rat model of early sepsis through the suppression of elevated levels of pulmonary endothelin-1
- Life sciences 166, 27-33, 2016-12
- NAID 120005899054
- Cyclic ADP-ribose and heat regulate oxytocin release via CD38 and TRPM2 in the hypothalamus during social or psychological stress in mice
- Frontiers in Neuroscience 10(JUL), 304, 2016-07
- NAID 120005851386
- Adiponectin Inhibits LPS-Induced HMGB1 Release through an AMP Kinase and Heme Oxygenase-1-Dependent Pathway in RAW 264 Macrophage Cells
- Mediators of inflammation 2016, 5701959, 2016-05-10
- NAID 120005822528
Related Pictures
★リンクテーブル★
| リンク元 | 「CD14」 |
「CD14」
LPSの受容 (SMB.117)
- LPSはマクロファージ、単球、顆粒球、Bリンパ球と反応し、多彩な生物活性を発現する。この反応には細胞表面のToll-like receptor。TLR-4がLPSのレセブタ-としてはたらき, LPSのシグナルを細胞内へと伝達する。このTLR-4の機能不全はLPSに対する応答性を失わせる。 TLR-4のほかに, CD14やMD-2と呼ばれる分子もLPSの認識に関与している。このTLRは分子群を形成し,ペプチドグリカン,リポタンパク質DNAなどの菌体成分を認識し,感染防御に重要なシグナルを伝達する。
発現細胞
- 骨髄性単球細胞
機能
- LPSの直接の受容体であり、Toll-like receptorとともに細胞内へのシグナル伝達に関わる。
- LPS-LBP複合体の受容体 ← 日本語がよく分かりません