WordNet

of a later stage in the development of a language or literature; used especially of dead languages; "Late Greek"
later than usual or than expected; "the train arrived late"; "we awoke late"; "the children came late to school"; "notice came so tardily that we almost missed the deadline"; "I belatedly wished her a happy birthday" (同)belatedly, tardily
at or toward an end or late period or stage of development; "the late phase of feudalism"; "a later symptom of the disease"; "later medical science could have saved the child" (同)later
of the immediate past or just previous to the present time; "a late development"; "their late quarrel"; "his recent trip to Africa"; "in recent months"; "a recent issue of the journal" (同)recent
at an advanced age or stage; "she married late"; "undertook the project late in her career"
being or occurring at an advanced period of time or after a usual or expected time; "late evening"; "late 18th century"; "a late movie"; "took a late flight"; "had a late breakfast"
having died recently; "her late husband"
the syllable naming the sixth (submediant) note of a major or minor scale in solmization (同)lah
abnormally low level of calcium in the blood; associated with hypoparathyroidism or kidney malfunction or vitamin D deficiency (同)hypocalcaemia

PrepTutorEJDIC

(定刻・通常・予定の時間より)『遅れた』,遅い / (時刻が)『遅い』,遅く始まる,遅くまで続く;夜更けの / (時期が)『遅い』,終りごろの,後期の / 『最近の』,最新の(recent) / 《the~,one's~》『前の』,先の,前任の(former) / 《the~,one's~》『故』…,つい先ごろ死んだ / (定刻などより)『遅れて』,遅く / (時刻が)『遅く』,遅くまで,(特に)夜更けに;(時期が)遅く,終りごろに / 『最近』,近ごろ(recently)
ラ(全音階の第6音)

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1. 幼児および小児における低カルシウム血症の病因 etiology of hypocalcemia in infants and children
2. 新生児低カルシウム血症 neonatal hypocalcemia
3. 低カルシウム血症への診断的アプローチ diagnostic approach to hypocalcemia
4. 成人における低カルシウム血症の原因 etiology of hypocalcemia in adults
5. 低カルシウム血症の治療 treatment of hypocalcemia

English Journal

Role of local vitamin D signaling and cellular calcium transport system in bone homeostasis.

Masuyama R.Author information Department of Molecular Bone Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, 852-8588, Japan, ritsuko@nagasaki-u.ac.jp.AbstractMouse genetic studies have demonstrated that the 1,25-dihydroxyvitamin D [1,25(OH)2D] endocrine system is required for calcium (Ca2+) and bone homeostasis. These studies reported severe hypocalcemia and impaired bone mineralization associated with rickets in mutant mice. Specific phenotypes of these mice with an engineered deletion of 1,25(OH)2D cell signaling resemble the features observed in humans with the same congenital disease or severe 1,25(OH)2D deficiency. Decreased active intestinal Ca2+ absorption because of reduced expression of epithelial Ca2+ channels is a crucial mechanism that contributes to the major phenotypes observed in the mutant mice. The importance of intestinal Ca2+ absorption supported by 1,25(OH)2D-mediated transport was further emphasized by the observation that Ca2+ supplementation rescues hypocalcemia and restores bone mineralization in both patients and mice lacking 1,25(OH)2D signaling. This observation questions the direct role of 1,25(OH)2D signaling in bone tissue. Studies regarding tissue-specific manipulation of 1,25(OH)2D function have provided a consensus on this issue by demonstrating a direct action of 1,25(OH)2D on cells in bone tissue through bone metabolism and mineral homeostasis. In addition, movement of Ca2+ from the bone as a result of osteoclastic bone resorption also provides a large Ca2+ supply in Ca2+ homeostasis; however, the system controlling Ca2+ homeostasis in osteoclasts has not been fully identified. Transient receptor potential vanilloid (TRPV) 4 mediates Ca2+ influx during the late stage of osteoclast differentiation, thereby regulating the Ca2+ signaling essential for cellular events during osteoclast differentiation; however, the system-modifying effect of TRPV4 activity should be determined. Furthermore, it remains unknown how local Ca2+ metabolism participates in systemic Ca2+ homeostasis through bone remodeling. New insights are therefore required to understand this issue.
Journal of bone and mineral metabolism.J Bone Miner Metab.2013 Nov 9. [Epub ahead of print]
Mouse genetic studies have demonstrated that the 1,25-dihydroxyvitamin D [1,25(OH)2D] endocrine system is required for calcium (Ca2+) and bone homeostasis. These studies reported severe hypocalcemia and impaired bone mineralization associated with rickets in mutant mice. Specific phenotypes of these
PMID 24213217

[The efficacy and safety of total thyroidectomy in the management of benign multinodular goiters].

Gál I, Solymosi T, Lukács-Tóth G, Wéber G.Author information Róbert Károly Magánklinika Sebészet Budapest.Abstractin

English, HungarianBevezetés: A megfelelő sebészi kezelési módszer vitatott a benignus multinodularis golyvák kezelésében. Klinikai tapasztalatainkról számolunk be, amelyeket a multinodularis golyvák total thyreoidectomiával történő kezelésében a műtétek kimenetelére, szövődményeire fókuszálva szereztünk, majd értékeljük a módszer hatásosságát és biztonságosságát. Anyag és módszer: Retrospektíve elemeztük 264, 2000 és 2006 között multinodularis golyva miatt total thyreoidectomiával kezelt beteg adatait. Vizsgáltuk a műtéti indikációkat, az átlagos kórházi ápolási időt, a korai és késői szövődményeket, a szövettani vizsgálat eredményeit különös tekintettel az incidentális pajzsmirigyrákok gyakoriságára és átlagosan 6,2 évvel a beavatkozást követően a rekurrencia előfordulását. Az eredményeket az irodalmi adatokhoz hasonlítottuk. Eredmények: A sebészeti beavatkozást 174 betegnél (65,9%) kompressziós és/vagy dislocatiós tünetek, 74-nél (28%) hyperthyreosis, a többinél kozmetikai probléma indokolta. Az átlagos kórházi ápolási idő 4 nap volt. Harmincegy betegnél (11,7%) alakult ki átmeneti hypocalcaemia, azonban ez csak 1-nél (0,3%) okozott klinikai tüneteket, és csupán 4 betegnél (1,5%) vált permanenssé. Egyéb szövődmények a 4 esetben (1,5%) kialakult haematoma, 7 esetben (2,6%) átmeneti egyoldali n. recurrens paresis – melyből 2 (0,75%) vált permanenssé – és a 8 (3%) betegnél észlelt seroma voltak. A szövettani vizsgálat 9 esetben (3,5%) fedezett fel incidentális pajzsmirigyrákot. Az utánkövetés során rekurrenciát nem észleltünk. Következtetés: A multinodularis golyvák sebészi kezelésében a total thyreoidectomia lehet a választandó műtéti eljárás.

Magyar sebészet.Magy Seb.2013 Oct;66(5):245-9. doi: 10.1556/MaSeb.66.2013.5.3.
in

English, HungarianBevezetés: A megfelelő sebészi kezelési módszer vitatott a benignus multinodularis golyvák kezelésében. Klinikai tapasztalatainkról számolunk be, amelyeket a multinodularis golyvák total thyreoidectomiával történő kezelésében a műtétek kimenetelére, szöv

PMID 24144816

Phenobarbitone versus phenytoin for treatment of neonatal seizures: an open-label randomized controlled trial.

Pathak G, Upadhyay A, Pathak U, Chawla D, Goel SP.Author information Department of Pediatrics, LLRM Medical College, Meerut;Department of Pediatrics, Government Medical College, Chandigarh; and Department of Pediatrics, Subharti Medical College, Meerut, UP, India. Correspondence to: Dr Amit Upadhyay, Department of Pediatrics, LLRM Medical College, Meerut, India. anuamit7@rediffmail.com.AbstractOBJECTIVE: To compare the efficacy of phenobarbitone and phenytoin for treatment of neonatal seizures in term and near-term neonates.
Indian pediatrics.Indian Pediatr.2013 Aug;50(8):753-7. Epub 2012 Dec 5.
OBJECTIVE: To compare the efficacy of phenobarbitone and phenytoin for treatment of neonatal seizures in term and near-term neonates.DESIGN: Open labeled randomized controlled trial.SETTING: Neonatal intensive care unit of a level II unit from India, from November 2008 to September 2009.PARTICIPANTS
PMID 23502660

Japanese Journal

消化管のビタミンD不応により新生児低Ca血症が遷延したと考えられた正期産不当軽量児の一例

太田栄治,山村健一郎,山本順子 [他],高橋保彦,城尾邦隆,小川厚,廣瀬伸一
福岡大学医学紀要 36(2), 121-126, 2009-06
NAID 110007089083

副甲状腺機能亢進症の母から出生し遅発性低カルシウム血症をきたした新生児の1例

村野一郎,蔵重秀樹,杉尾陽子,井上康
日本新生児学会雑誌 37(4), 690-692, 2001-12-01
NAID 10007861818

Primary Hypomagnesemia Caused by Isolated Magnesium Malabsorption : Atypical Case in Adult

Jin-no Yasunari,Kamiya Yoshinobu,Okada Masami [他],HIRAKO Makoto,TAKADA Norio,KAWAGUCHI Masanobu
Internal medicine 38(3), 261-265, 1999-03
… Hypomagnesemia and hypocalcemia were found in a 35-year-old man with muscle cramps, who bad been diagnosed as primary hypoparathyroidism. …
NAID 10005896737