WordNet

with the wind abaft the beam; "a ship sailing large"
a garment size for a large person
above average in size or number or quantity or magnitude or extent; "a large city"; "set out for the big city"; "a large sum"; "a big (or large) barn"; "a large family"; "big businesses"; "a big expenditure"; "a large number of newspapers"; "a big group of scientists"; "large areas of the world" (同)big
at a distance, wide of something (as of a mark)
fairly large or important in effect; influential; "played a large role in the negotiations"
having broad power and range and scope; "taking the large view"; "a large effect"; "a large sympathy"
stimulating evacuation of feces
a mild cathartic
the part of the alimentary canal between the stomach and the anus (同)bowel, gut

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Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.

Chassaing B1, Koren O2, Goodrich JK3, Poole AC3, Srinivasan S4, Ley RE3, Gewirtz AT1.
Nature.Nature.2015 Mar 5;519(7541):92-6. doi: 10.1038/nature14232. Epub 2015 Feb 25.
The intestinal tract is inhabited by a large and diverse community of microbes collectively referred to as the gut microbiota. While the gut microbiota provides important benefits to its host, especially in metabolism and immune development, disturbance of the microbiota-host relationship is associa
PMID 25731162

Karlov AV, Orlova NV, Parfenov AI.
Terapevticheskiĭ arkhiv.Ter Arkh.2015;87(4):53-7.
AIM: To define the rate and type distribution of dyssynergic defecation (DD) in patients with primary chronic constipation (CC) and to evaluate the efficiency of biofeedback (BFB) therapy.SUBJECTS AND METHODS: One hundred and thirty-two 18-to-89-year-old patients treated in the Moscow Clinical Resea
PMID 26087635

A systematic review: effectiveness of rectal emptying preparation in prostate cancer patients.

McNair HA1, Wedlake L2, Lips IM3, Andreyev J4, Van Vulpen M3, Dearnaley D5.
Practical radiation oncology.Pract Radiat Oncol.2014 Nov-Dec;4(6):437-47. doi: 10.1016/j.prro.2014.06.005. Epub 2014 Aug 3.
While the importance of a consistent rectal volume during radiation therapy planning and treatment for patients receiving radiation therapy to the prostate is recognized, there is no clear guidance as to the most effective method. This review examines the evidence for the efficacy of rectal preparat
PMID 25407867

貞広荘太郎,大村敏郎,山田良成,斉藤敏明,瀧康紀
日本大腸肛門病学会雑誌 46(2), 111-115, 1993
排便習慣に影響を与える因子を検索するため,注腸検査を受けた920例を対象として,年齢,・性別,大腸全体の長さ,表面積,S状結腸の形成するループ数と排便回数,下剤使用の有無との関係を分析した.男性の67.8%,女性の53.6%では排便回数は1日1～2回であり,男性の77.6%,女性の71.9%では排便回数は1日に1～2回あるいは2～3日間に1回であった.男性では年齢が高くなると排便回数が減少し下剤の …
NAID 130000783700