高浸透圧高血糖症候群 hyperosmolar hyperglycemic nonketotic syndrome HHNS = 高血糖高浸透圧症候群 HHS

WordNet

a pattern of symptoms indicative of some disease
a complex of concurrent things; "every word has a syndrome of meanings"

PrepTutorEJDIC

(疾患の徴候となる一群の)症徴候,症候群 / (事件・社会的状態などのパターンを示す)徴候形態

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 成人における糖尿病性ケトアシドーシスおよび高浸透圧性高血糖状態：臨床的特徴、評価、および診断 diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults clinical features evaluation and diagnosis
2. 成人における糖尿病性ケトアシドーシスおよび高浸透圧性高血糖状態：治療 diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults treatment
3. 成人における糖尿病性ケトアシドーシスおよび高浸透圧性高血糖状態：疫学および病因 diabetic ketoacidosis and hyperosmolar hyperglycemic state in adults epidemiology and pathogenesis
4. 小児および思春期における2型糖尿病の疫学、症状、および診断 epidemiology presentation and diagnosis of type 2 diabetes mellitus in children and adolescents
5. Anesthesia for renal transplantation

English Journal

[Management of hyperglycemic crises and severe hypoglycemia in the emergency department].

Miyake Y.Author information Emergency and Critical Care Medicine, Showa University School of Medicine.AbstractAbstract The morbidity of hyperglycemic crises and acute hypoglycemic attacks in patients with diabetes mellitus has been increasing for the past several decades. One of the reasons for this is the increase in the number of patients with diabetes. The increased proportion of aging and isolation in society is another reason. The author has discussed patients with these complaints: their epidemiology, pathophysiology, and management in the emergency department. Hyperglycemic crises include diabetic ketoacidosis (DKA), hyperosmolar hyperglycemic syndrome (HHS), and lactic acidosis (LA). Younger patients with type 1 diabetes suffer from DKA; inappropriate insulin therapy or infection is usually the trigger. Older patients with type 2 diabetes are at risk of HHS in the course of sepsis or in the perioperative period. The treatment of both types of patients is common. Sufficient amount of intravenous extracellular fluid and constant infusion of insulin are essential. The development of LA is not associated with the use of metformin, but with the severity of the pre-existing disease. Early recognition and aggressive treatment is vital to improving the prognosis of hyperglycemic emergencies and severe hypoglycemic episodes.
Brain and nerve = Shinkei kenkyū no shinpo.Brain Nerve.2014 Feb;66(2):97-105.
Abstract The morbidity of hyperglycemic crises and acute hypoglycemic attacks in patients with diabetes mellitus has been increasing for the past several decades. One of the reasons for this is the increase in the number of patients with diabetes. The increased proportion of aging and isolation in s
PMID 24523308

[Sick day management in elderly patients with diabetes mellitus].

Suzuki S.Author information Diabetes Center, Ohta Nishinouchi Hospital.AbstractA bad cold, the flu or a serious illness can make blood glucose too high in elderly person with diabetes. Gastrointestinal illnesses may cause hypoglycemia for individuals treated with insulin, sulfonylureas or glitinides. When the persons with diabetes discontinue insulin or diabetes medications because of appetite loss and reduced food intake, they may fall into diabetic crises, such as ketoacidosis, or hyperosmolar hyperglycemic syndrome. The elderly patients need to take extra precautions on sick days to avoid diabetic crises or hypoglycemia. Key principles of sick day management are (1) maintaining hydration and carbohydrate intake, (2) monitoring blood glucose and ketone levels, (3) adjusting diabetes medications according to carbohydrate intake, blood glucose and ketone levels. In Japan, the numbers of frail elderly diabetic patients is markedly increased, effective and efficient sick day management for frail elderly diabetic patients is requested.
Nihon rinsho. Japanese journal of clinical medicine.Nihon Rinsho.2013 Nov;71(11):2020-4.
A bad cold, the flu or a serious illness can make blood glucose too high in elderly person with diabetes. Gastrointestinal illnesses may cause hypoglycemia for individuals treated with insulin, sulfonylureas or glitinides. When the persons with diabetes discontinue insulin or diabetes medications be
PMID 24397177

Evaluation of point-of-care blood glucose measurements in patients with diabetic ketoacidosis or hyperglycemic hyperosmolar syndrome admitted to a critical care unit.

Corl DE1, Yin TS, Mills ME, Spencer TL, Greenfield L, Beauchemin E, Cochran J, Suhr LD, Thompson RE, Wisse BE.Author information 1Clinical Education, Harborview Medical Center, 325 Ninth Ave., UW box 359733, Seattle, WA 98104-2499. corld@uw.edu.AbstractBACKGROUND: Point-of-care (POC) blood glucose (BG) measurement is currently not recommended in the treatment of patients presenting with diabetic ketoacidosis (DKA) or hyperglycemic hyperosmolar syndrome (HHS).
Journal of diabetes science and technology.J Diabetes Sci Technol.2013 Sep 1;7(5):1265-74.
BACKGROUND: Point-of-care (POC) blood glucose (BG) measurement is currently not recommended in the treatment of patients presenting with diabetic ketoacidosis (DKA) or hyperglycemic hyperosmolar syndrome (HHS).METHODS: We prospectively evaluated and compared capillary and venous POC BG values with l
PMID 24124953

Japanese Journal

糖尿病の治療の原則と実際:高血糖・低血頭への緊急対応 (糖尿病のリハビリテーション実践マニュアル)

宮崎博子
Monthly book medical rehabilitation (117), 59-70, 2010-04
NAID 40017104869

高齢者に生じた高ケトン血症を伴った高浸透圧高血糖症候群の1例

和泉賢一,村上一雄
日本老年医学会雑誌 46(1), 79-84, 2009-01-25
NAID 10024963798

「高浸透圧高血糖症候群」

　　[★]

英: hyperosmolar hyperglycemic nonketotic syndrome
同: 高血糖高浸透圧症候群 hyperglycemic hyperosmolar syndrome HHS、非ケトン性高浸透圧性症候群　← 以前の呼称らしい
関: 高浸透圧性非ケトン性昏睡? hyperosmolar nonketotic coma?。糖尿病

[show details]

高浸透圧高血糖症候群 : 約 5,680 件
高血糖高浸透圧症候群 : 約 10,800 件

研修医当直御法度症例帳 p.18

2型糖尿病

誘発因子

糖尿病専門医研修ガイドブック改訂第4版 p.190

感染症：肺炎、尿路感染症、ウイルス感染
脱水：嘔吐、下痢
手術：胸部手術、腹部手術、脳外科手術
脳血管障害：脳梗塞、脳出血
薬剤：ステロイド、利尿薬、高カロリー輸液
内分泌疾患：Cushing syndrome、バセドウ病
心疾患：心筋梗塞、心不全

比較

糖尿病専門医研修ガイドブック改訂第4版 p.190

		DKA	HONK
糖尿病病型		1型糖尿病	2型糖尿病
発症年齢		若年	高齢
前駆症状		多飲、多尿、消化器症状	特異的なものはない
身体異常		脱水、アセトン臭、クスマウル大呼吸	脱水、アセトン臭－、中枢神経症状(痙攣、振戦)
検査所見	尿ケトン体	(＋)～（＋＋）	（－）～（±）
	血糖値(mg/dL)	300～1000	600～1500
	浸透圧(mOsm/L)	＞300	＞350
	Na (mEq/L)	正常～軽度低下	＞150mEq/L
	pH	＜7.3	7.3～7.4
	BUN	上昇	著明上昇
	K	↑	↑