"Hypotonic" redirects here. For the muscular disease, see Hypotonia.
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Effect of different solutions on blood cells
Micrographs of osmotic pressure on red blood cells
Tonicity is a measure of the osmotic pressure gradient (as defined by the water potential of the two solutions) of two solutions separated by a semipermeable membrane. It is commonly used when describing the response of cells immersed in an external solution. Like osmotic pressure, tonicity is influenced only by solutes that cannot cross the membrane, as only these exert an osmotic pressure. Solutes able to freely cross the membrane do not affect tonicity because they will always be in equal concentrations on both sides of the membrane.
There are three classifications of tonicity that one solution can have relative to another. The three are hypertonic, hypotonic, and isotonic.
- 1 Hypertonicity
- 2 Hypotonicity
- 3 Isotonicity
- 4 See also
- 5 References
Hypertonic refers to a greater concentration. In biology, a hypertonic solution is one with a higher concentration of solutes on the outside of the cell. When a cell is immersed into a hypertonic solution, the tendency is for water to want to flow out of the cell in order to balance the concentration of the solutes.
However, a hypertonic cell has a higher concentration of solutes than the surrounding solution, causing water to rush into the cell in an effort to balance out the concentration of solutes. The affinity of water wanting to rush in can be quantified as the osmotic pressure.
Hypotonic refers to a lesser concentration. A hypotonic cell has a lower concentration of solutes than its surroundings, so in an attempt to balance concentrations, water will rush out of the cell, causing crenation. The cell becomes wrinkled and distorted.
When plant cells are hypotonic, the flexible cell membrane pulls away from the rigid cell wall, but remains joined to the cell wall at points called plasmodesmata. The cell takes on the appearance of a pincushion, and the plasmodesmata almost cease to function because they become constricted: a condition known as plasmolysis. In plant cells the terms isotonic, hypotonic and hypertonic cannot strictly be used accurately because the pressure exerted by the cell wall significantly affects the osmotic equilibrium point.
Some organisms have evolved intricate methods of circumventing hypotonicity. For example, saltwater is hypertonic to the fish that live in it. They need a large surface area in their gills in contact with seawater for gas exchange, thus they lose water osmotically to the sea from gill cells. They respond to the loss by drinking large amounts of saltwater, and actively excreting the excess salt. This process is called osmoregulation.
A hypertonic solution is used in osmotherapy to treat cerebral hemorrhage.
An isotonic solution is one in which its effective osmole concentration is the same as the solute concentration of another solution with which it is compared. This occurs, for example, when the concentration of both water and total solute molecules are the same in an external solution as in the cell content. Water molecules diffuse through the plasma membrane in both directions, and as the rate of water diffusion is the same in both direction that cell will neither gain nor lose water.
- ^ Sperelakis, Nicholas (2011). Cell Physiology Source Book: Essentials of Membrane Biophysics. Academic Press. pp. 288. ISBN 978-0-12-387738-3.
- ^ Brandis, Kerry. "Fluid Physiology". http://www.anaesthesiamcq.com/FluidBook/fl2_3.php. Retrieved 11/22/2012.
- ^ "Definition — hypotonic". The Free Dictionary. http://medical-dictionary.thefreedictionary.com/hypotonic. Retrieved 23 August 2012.