肝細胞核因子
- 関
- HNF
WordNet
- be a contributing factor; "make things factor into a companys profitability"
- any of the numbers (or symbols) that form a product when multiplied together
- an independent variable in statistics
- anything that contributes causally to a result; "a number of factors determined the outcome"
- consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
- resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
- an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
- a concept whose truth can be proved; "scientific hypotheses are not facts"
- a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
- a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
- of or relating to or constituting the nucleus of an atom; "nuclear physics"; "nuclear fission"; "nuclear forces"
- (weapons) deriving destructive energy from the release of atomic energy; "nuclear war"; "nuclear weapons"; "atomic bombs" (同)atomic
- constituting or like a nucleus; "annexation of the suburban fringe by the nuclear metropolis"; "the nuclear core of the congregation"
- of or relating to or constituting the nucleus of a cell; "nuclear membrane"; "nuclear division"
PrepTutorEJDIC
- (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
- 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
- 『核の』,細胞核の / [『原子』]『核の』
UpToDate Contents
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- 1. 糖尿病および遺伝的糖尿病症候群の分類classification of diabetes mellitus and genetic diabetic syndromes [show details]
…several countries offer clinical testing, primarily for mutations in hepatocyte nuclear factor-4-alpha (HNF4A), hepatocyte nuclear factor-1-alpha (HNF1A), and the glucokinase (GCK) gene. We typically perform …
- 2. 低マグネシウム血症の原因causes of hypomagnesemia [show details]
…of 18 patients (44 percent) with known mutations in the hepatocyte nuclear factor-1-beta (HNF-1-beta) gene . HNF-1-beta is a transcription factor that regulates the expression of the gamma subunit of Na-K-ATPase …
- 3. 乳児期に生じる持続性高インスリン血症性低血糖症の病因、臨床的特徴、診断pathogenesis clinical features and diagnosis of persistent hyperinsulinemic hypoglycemia of infancy [show details]
…(SCHAD), which interacts with glutamate dehydrogenase; HNF1A gene (hepatocyte nuclear factor 1-alpha) HNF4A gene (hepatocyte nuclear factor 4-alpha) SLC16A1 gene (solute carrier family 16, member 1; also …
- 4. 赤血球産生調節regulation of erythropoiesis [show details]
…and for their presence in transcription complexes isolated from Hep 3B nuclear extracts. One of these, hepatocyte nuclear factor 4 (HNF-4) is present in these extracts and plays a critical role in hypoxia-induced …
- 5. 血友病Aおよび血友病Bの遺伝学的特徴genetics of hemophilia a and b [show details]
…liver-enriched hepatocyte nuclear factor 4 (HNF4/LF-A1) and Ets1 . The pubertal hormone that causes these transcription factors to increase appears to be growth hormone, rather than androgens. In one instructive …
English Journal
- Olanzapine modulation of hepatic oxidative stress and inflammation in socially isolated rats.
- Todorović N1, Tomanović N2, Gass P3, Filipović D4.
- European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.Eur J Pharm Sci.2016 Jan 1;81:94-102. doi: 10.1016/j.ejps.2015.10.010. Epub 2015 Oct 19.
- Olanzapine, an atypical antipsychotic, is efficient in stress associated psychiatric diseases, but its effect on the liver, a primary organ for drug activation and detoxification, still remains unclear. The effect of olanzapine administration (7.5mg/kg/day), on rat hepatic glutathione (GSH)-dependen
- PMID 26474692
- Repression of HNF1α-mediated transcription by amino-terminal enhancer of split (AES).
- Han EH1, Gorman AA2, Singh P1, Chi YI3.
- Biochemical and biophysical research communications.Biochem Biophys Res Commun.2015 Dec 4;468(1-2):14-20. doi: 10.1016/j.bbrc.2015.11.007. Epub 2015 Nov 6.
- HNF1α (Hepatocyte Nuclear Factor 1α) is one of the master regulators in pancreatic beta-cell development and function, and the mutations in Hnf1α are the most common monogenic causes of diabetes mellitus. As a member of the POU transcription factor family, HNF1α exerts its gene regulatory functi
- PMID 26549228
- Circulating ghrelin level is higher in HNF1A-MODY and GCK-MODY than in polygenic forms of diabetes mellitus.
- Nowak N1,2, Hohendorff J1,3, Solecka I3, Szopa M1,3, Skupien J1,3, Kiec-Wilk B1,3, Mlynarski W4, Malecki MT5,6.
- Endocrine.Endocrine.2015 Dec;50(3):643-9. doi: 10.1007/s12020-015-0627-5. Epub 2015 May 19.
- Ghrelin is a hormone that regulates appetite. It is likely to be involved in the pathophysiology of varying forms of diabetes. In animal studies, the ghrelin expression was regulated by the hepatocyte nuclear factor 1 alpha (HNF1A). Mutations of the HNF1A gene cause maturity onset diabetes of the yo
- PMID 25987348
Japanese Journal
- 2) 顆粒膜細胞における細胞内信号伝達系分子の活性化機序と排卵誘発への応用(シンポジウム1(生殖) 卵巣のダイナミックな変化の神秘に迫る-臨床へのフィードバックを目指して-,第67回日本産科婦人科学会学術講演会講演要旨)
- Hepatic stellate cells relay inflammation signaling from sinusoids to parenchyma in mouse models of immune-mediated hepatitis.
- 肝生検で高分化型肝細胞癌との鑑別が困難であった多発肝細胞腺腫の1切除例
Related Links
- The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor ...
- 1. Biomed Rep. 2013 Jan;1(1):13-17. Epub 2012 Oct 11. Hepatocyte nuclear factor (HNF)-1β and its physiological importance in endometriosis. Akasaka J(1), Uekuri C(1), Shigetomi H(1), Koike M(1), Kobayashi H(1). Author ...
Related Pictures
★リンクテーブル★
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- 関
- hepatocyte nuclear factor
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- 英
- hepatocyte nuclear factor、HNF
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- 関
- hepatocyte nuclear factor 1alpha、HNF-1alpha
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- 関
- HNF-3alpha
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- 関
- HNF-1beta
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- 関
- HNF-3beta
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- 関
- HNF-1
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- 関
- cell nuclei、cell nucleus、nuclei、nucleo、nucleus
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- 関
- actual、actually、in fact、in practice、indeed、practically
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- 関
- element、elementary、factorial、parameter
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