Current perspectives on FOXA1 regulation of androgen receptor signaling and prostate cancer.
Yang YA1, Yu J2.
Genes & Diseases.Genes Dis.2015 Jun;2(2):144-151.
FOXA1 (also known as hepatocyte nuclear factor 3α, or HNF-3α) is a protein of the FKHD family transcription factors. FOXA1 has been termed as a pioneer transcription factor due to its unique ability of chromatin remodeling in which the chromatin can be decompacted to allow genomic access by nuclea
Synergistic effect of caffeine and glucocorticoids on expression of surfactant protein B (SP-B) mRNA.
Fehrholz M1, Bersani I, Kramer BW, Speer CP, Kunzmann S.
PloS one.PLoS One.2012;7(12):e51575. doi: 10.1371/journal.pone.0051575. Epub 2012 Dec 14.
Administration of glucocorticoids and caffeine is a common therapeutic intervention in the neonatal period, but possible interactions between these substances are still unclear. The present study investigated the effect of caffeine and different glucocorticoids on expression of surfactant protein (S
Overexpression of hepatocyte nuclear factor-3alpha induces apoptosis through the upregulation and accumulation of cytoplasmic p53 in prostate cancer cells.
Lee HJ1, Chattopadhyay S, Yoon WH, Bahk JY, Kim TH, Kang HS, Lee K.
The Prostate.Prostate.2010 Mar 1;70(4):353-61. doi: 10.1002/pros.21069.
BACKGROUND: Hepatocyte nuclear factor-3alpha (HNF-3alpha) has been known to act as a repressor in the pathogenesis of many cancers. Herein, we investigated the effect of HNF-3alpha overexpression in prostate cancer cells.METHODS: HNF-3alpha was overexpressed in prostate cancer cells using an adenovi
HNF-3 alpha Antibody (Q-6) is a high quality mouse monoclonal recommended for detecting HNF-3 alpha of human origin by WB, IP, IF, IHC(P) and ELISA ... HNF-3α Antibody (Q-6) is a mouse monoclonal IgG 2a provided at 100 µg ...