hepatocyte nuclear factor 1

• 肝細胞核因子1

関

HNF-1

WordNet

1. be a contributing factor; "make things factor into a companys profitability"
2. any of the numbers (or symbols) that form a product when multiplied together
3. an independent variable in statistics
4. anything that contributes causally to a result; "a number of factors determined the outcome"
5. consider as relevant when making a decision; "You must factor in the recent developments" (同)factor in, factor out
6. resolve into factors; "a quantum computer can factor the number 15" (同)factor in, factor out
7. an event known to have happened or something known to have existed; "your fears have no basis in fact"; "how much of the story is fact and how much fiction is hard to tell"
8. a concept whose truth can be proved; "scientific hypotheses are not facts"
9. a piece of information about circumstances that exist or events that have occurred; "first you must collect all the facts of the case"
10. a statement or assertion of verified information about something that is the case or has happened; "he supported his argument with an impressive array of facts"
11. of or relating to or constituting the nucleus of an atom; "nuclear physics"; "nuclear fission"; "nuclear forces"
12. (weapons) deriving destructive energy from the release of atomic energy; "nuclear war"; "nuclear weapons"; "atomic bombs" (同)atomic
13. constituting or like a nucleus; "annexation of the suburban fringe by the nuclear metropolis"; "the nuclear core of the congregation"
14. of or relating to or constituting the nucleus of a cell; "nuclear membrane"; "nuclear division"

PrepTutorEJDIC

1. (…の)『要因』,(…を生み出す)要素《+『in』+『名』(do『ing』)》 / 囲数,約数 / 代理人,《おもに英》仲買人 / =factorize
2. 〈C〉『事実』,実際にある(あった)事 / 〈U〉真相,真実(truth) / 《the~》(法律用語で)犯行
3. 『核の』,細胞核の / [『原子』]『核の』

UpToDate Contents

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• 1. 糖尿病および遺伝的糖尿病症候群の分類 classification of diabetes mellitus and genetic diabetic syndromes
• 2. 幼児の持続性高インスリン血症性低血糖症の病因、臨床的特徴、および診断 pathogenesis clinical features and diagnosis of persistent hyperinsulinemic hypoglycemia of infancy
• 3. 微細欠失症候群（12番～22番染色体） microdeletion syndromes chromosomes 12 to 22
• 4. Osteoclast inhibitors in the management of bone metastases from breast cancer
• 5. 高リスク (浸潤性) 皮膚扁平上皮癌の認識およびマネージメント recognition and management of high risk aggressive cutaneous squamous cell carcinoma

English Journal

• High-Sensitivity CRP Discriminates HNF1A-MODY From Other Subtypes of Diabetes.

• McDonald TJ, Shields BM, Lawry J, Owen KR, Gloyn AL, Ellard S, Hattersley AT.SourcePeninsula College of Medicine and Dentistry (University of Exeter), Peninsula NIHR Clinical Research Facility, Exeter, Devon, U.K.
• Diabetes care.Diabetes Care.2011 Jun 23. [Epub ahead of print]
• OBJECTIVE Maturity-onset diabetes of the young (MODY) as a result of mutations in hepatocyte nuclear factor 1-α (HNF1A) is often misdiagnosed as type 1 diabetes or type 2 diabetes. Recent work has shown that high-sensitivity C-reactive protein (hs-CRP) levels are lower in HNF1A-MODY than type 1 dia
• PMID 21700917

• Onset of type 1 diabetes mellitus in two patients with maturity onset diabetes of the young.

• Maltoni G, Zucchini S, Scipione M, Mantovani V, Salardi S, Cicognani A.SourceDepartment of Pediatrics, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy Center for Applied Biomedical Research and Medical Genetics Unit, S. Orsola-Malpighi Hospital, Bologna, Italy.
• Pediatric diabetes.Pediatr Diabetes.2011 Jun 23. doi: 10.1111/j.1399-5448.2011.00788.x. [Epub ahead of print]
• Maltoni G, Zucchini S, Scipione M, Mantovani V, Salardi S, Cicognani A. Onset of type 1 diabetes mellitus in two patients with maturity onset diabetes of the young. The association between maturity onset diabetes of the young (MODY) and type 1 diabetes mellitus (T1DM) has been rarely described. We r
• PMID 21696527

Japanese Journal

• 複雑性尿路感染症を合併したMODY5の1例

• 青木 絵麻,滝澤 美保,柳沢 慶香,原田 真耶,花井 豪,石井 晶子,家後 理枝,岩崎 直子,岩本 安彦
• 東京女子医科大学雑誌 81(E2), E247-E252, 2011-03-31
• 症例は50歳、女性。25歳時糖尿病と診断されインスリン療法を開始された。その際に左腎萎縮と両腎嚢胞を指摘された。糖尿病診断当初インスリン分泌能は保たれており、治療開始後1年から3年の間は一時的に経口血糖降下薬で血糖コントロール可能であったが、徐々に内因性インスリン分泌は低下し、現在はほぼ枯渇している。母親に糖尿病、姉に耐糖能障害を認め,両腎嚢胞とインスリン分泌不全などの特徴から臨床的にMODY5が …
• NAID 110008441476

• 糖尿病とミトコンドリア機能

• 尾形 真規子
• 東京女子医科大学雑誌 81(E2), E85-E88, 2011-03-31
• … MODY3遺伝子産物Hepatocyte nuclear factor(HNF)1αもβ細胞のミトコンドリア機能に大きく関与することが報告されており、我々の培養β細胞を用いた結果では、MODY1原因として報告されているQ268X 変異HNF4α遺伝子の導入によりβ細胞のミトコンドリア機能異常を起こしている。 …
• NAID 110008441449

Related Links

• Hepatocyte nuclear factors - Wikipedia, the free encyclopedia

"Mutations in the human genes encoding the transcription factors of the hepatocyte nuclear factor (HNF)1 and HNF4 families: functional and pathological consequences". J Mol Endocrinol 27 (1): 11?29. doi:10.1677/jme.0.0270011. ...

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★リンクテーブル★

リンク元	「HNF-1」「肝細胞核因子1」
拡張検索	「hepatocyte nuclear factor 1-alpha」「hepatocyte nuclear factor 1-beta」
関連記事	「nuclear」「fact」「factor」「nuclear factor」

「HNF-1」

　　[★]

• 肝細胞核因子1

関

hepatocyte nuclear factor 1

「肝細胞核因子1」

　　[★]

英

hepatocyte nuclear factor 1、HNF-1

「hepatocyte nuclear factor 1-alpha」

　　[★]

• 肝細胞核因子1α

関

hepatocyte nuclear factor 1alpha、HNF-1alpha

「hepatocyte nuclear factor 1-beta」

　　[★]

• 肝細胞核因子1β

関

HNF-1beta

「nuclear」

　　[★]

• adj.

• 核の、(生物)細胞核の、(物理)原子核の

関

cell nuclei、cell nucleus、nuclei、nucleo、nucleus

　 　 　 　 　

「fact」

　　[★]

• n.

• 事実、現状、実際、実態

関

actual、actually、in fact、in practice、indeed、practically

　 　 　 　 　

「factor」

　　[★]

• n.

• 因子、要因、要素、ファクター

関

element、elementary、factorial、parameter

　 　 　 　 　 　 　

「nuclear factor」

　　[★]

• 核内転写因子、核内因子、核因子