関: first-dose phenomenon

WordNet

travel or traverse (a distance); "This car does 150 miles per hour"; "We did 6 miles on our hike every day"
the syllable naming the first (tonic) note of any major scale in solmization (同)doh, ut
proceed or get along; "How is she doing in her new job?"; "How are you making out in graduate school?"; "Hes come a long way" (同)fare, make_out, come, get along
create or design, often in a certain way; "Do my room in blue"; "I did this piece in wood to express my love for the forest" (同)make
carry on or function; "We could do with a little more help around here" (同)manage
get (something) done; "I did my job" (同)perform
preceding all others in time or space or degree; "the first house on the right"; "the first day of spring"; "his first political race"; "her first baby"; "the first time"; "the first meetings of the new party"; "the first phase of his training"
the first or highest in an ordering or series; "He wanted to be the first" (同)number_one
the first element in a countable series; "the first of the month" (同)number_one, number 1
an honours degree of the highest class (同)first-class honours degree
indicating the beginning unit in a series (同)1st
before anything else; "first we must consider the garter snake" (同)firstly, foremost, first of all, first off
the initial time; "when Felix first saw a garter snake" (同)for_the_first_time
ranking above all others; "was first in her class"; "the foremost figure among marine artists"; "the top graduate" (同)foremost, world-class
before another in time, space, or importance; "I was here first"; "lets do this job first"
highest in pitch or chief among parts or voices or instruments or orchestra sections; "first soprano"; "the first violin section"; "played first horn"
treat with an agent; add (an agent) to; "The ray dosed the paint"
the quantity of an active agent (substance or radiation) taken in or absorbed at any one time (同)dosage
a measured portion of medicine taken at any one time (同)dosage
any of various evergreen trees of the genus Abies; chiefly of upland areas (同)fir_tree, true fir
nonresinous wood of a fir tree

PrepTutorEJDIC

《疑問文・否定文を作る》 / 《否定命令文を作る》 / 《助動詞とbe動詞のどちらも含まない文に用いて付加疑問を作る》 / 《強意語として》 / 《文》《助動詞とbe動詞のどちらも含まない文に用いて倒置文を作る》 / 《あいづちを打つ場合に》 / 《先行する動詞またはそれを含む述部の代用》 / 《so,nor,neitherで始まる簡略文で》 / …‘を'『する』,行う,果たす / 《通例have done,時にbe doneの形で》…‘を'『終える』,済ませる / …‘を'作る,作り出す / …‘を'『処理する』,整える,片付ける / 〈学課〉‘を'『勉強する』,専攻する / 〈利益・害など〉‘を'与える,もたらす / 〈人〉‘に'『役立つ』,用が足りる(serve) / …の速度で進む,距離を行く / …‘を'見物する / 〈劇〉‘を'上演する;…‘の'役を演じる / …の役目(仕事)をする / 《おもに英》…‘を'だます,かつぐ / 《話》…をへとへとにさせる / 『する』;活動する / 《通例have done,時にbe doneの形で》(…を)『終える』,済ます《+『with』+『名』》 / 〈事が〉『運ぶ』;〈人が〉暮らしていく,健康である / 〈物が〉(…に)『間に合う』,十分である;〈人が〉(…に)役に立つ,向く《+『for』+『名』》 / 《複数形で》すべきこと / 〈C〉《おもに英》大宴会,大パーティー / 〈C〉《英話》詐欺,ぺてん
ド(全音階の第1音)
(順序・時間的に)『第1の』,1番目の;最初の / (階級・等級・重要度などが)『1番の』,第一級の,首席の,最も重要な / 『最初に』,まっ先に;1番目に,第1位に;初めて / (…するくらいなら)むしろ,いっそ(…のほうがいい)(rather, sooner) / 《通例the~》『最初のもの』;(月の)第1日;(時代の)第1年 / 《通例the~》初め,始まり / 〈U〉ファーストギヤ,低速ギヤ / 〈C〉《英》(競技などの)第1位,1等(試験の)第一級 / 《複数形で》最高級品,一級品 / 〈U〉=first base
(おもに飲み薬1回分の)『服用量』 / (痛いこと・いやなことの)1回分,一定量 / (人などが受ける放射線の)線量 / 性病 / (…を)…‘に'投薬する,服用させる《+『名』+『with』+『名』》
モミ,モミの木(クリスマスツリーに用いられる) / モミ材
phenomenonの複数形

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English Journal

Selective cyclooxygenase-2 inhibition reduces endothelial dysfunction and improves inflammatory status in patients with intermittent claudication.

Flórez A, de Haro J, Martínez E, Varela C, Bleda S, Acín F.SourceServicio de Angiología y Cirugía Vascular. Hospital Universitario de Getafe. Getafe. Madrid. España. aurora.florez@terra.es
Revista española de cardiología.Rev Esp Cardiol.2009 Aug;62(8):851-7.
INTRODUCTION AND OBJECTIVES: Both endothelial dysfunction and a proinflammatory state are present during the early stages of atherosclerosis. In this context, increased expression of cyclooxygenase-2 (COX-2) results in higher levels of vasoconstrictive and proinflammatory substances. The aim of this
PMID 19706240

PKPD model of interleukin-21 effects on thermoregulation in monkeys--application and evaluation of stochastic differential equations.

Overgaard RV, Holford N, Rytved KA, Madsen H.SourceInformatics and Mathematical Modelling, Technical University of Denmark, Richard Petersens Plads, Building 321, Room 015, Kongens Lyngby 2800, Denmark. ruvo@novonordisk.com
Pharmaceutical research.Pharm Res.2007 Feb;24(2):298-309. Epub 2006 Sep 29.
PURPOSE: To describe the pharmacodynamic effects of recombinant human interleukin-21 (IL-21) on core body temperature in cynomolgus monkeys using basic mechanisms of heat regulation. A major effort was devoted to compare the use of ordinary differential equations (ODEs) with stochastic differential
PMID 17009101

Sympatho-excitatory responses to once-daily dihydropyridines in young versus older hypertensive patients: amlodipine versus felodipine extended release.

Leenen FH, Coletta E, White R.SourceHypertension Unit, University of Ottawa Heart Institute, Ottawa, Ontario, Canada. fleenan@ottawaheart.ca
Journal of hypertension.J Hypertens.2006 Jan;24(1):177-84.
BACKGROUND: Once-daily dihydropyridines exert both indirect sympatho-excitatory and direct central sympatho-inhibitory effects. Age may affect this balance by influencing blood pressure (BP) or renin responses.METHODS: We evaluated BP, sympathetic and cardiac responses after the first dose and after
PMID 16331116