WordNet

act so as to bring into existence; "effect a change"
a symptom caused by an illness or a drug; "the effects of sleep loss"; "the effect of the anesthetic"
(of a law) having legal validity; "the law is still in effect" (同)force
the central meaning or theme of a speech or literary work (同)essence, burden, core, gist
an impression (especially one that is artificial or contrived); "he just did it for effect"
produce; "The scientists set up a shock wave" (同)effectuate, set_up
a nerve fiber that terminates on a muscle or gland and stimulates contraction or secretion
an organ (a gland or muscle) that becomes active in response to nerve impulses
any of a group of proteases that mediate apoptosis

PrepTutorEJDIC

〈C〉〈U〉『結果』 / 〈C〉〈U〉(…への)『効果』,効きめ,影響《+『on』(『upon』)+『名』》 / 〈C〉(色・音・形などの)印象,感銘 / 《複数形で》品物;身の回り品;動産,財産 / (結果として)…‘を'『もたらす』;〈目的など〉‘を'果たす,遂行する

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

1. 複合免疫不全 combined immunodeficiencies
2. アポトーシスと自己免疫疾患 apoptosis and autoimmune disease
3. 赤痢菌感染：疫学、微生物学、および病因 shigella infection epidemiology microbiology and pathogenesis
4. 適応細胞性免疫応答 the adaptive cellular immune response
5. 混合性結合組織病における抗U1-RNP抗体 anti u1 rnp antibodies in mixed connective tissue disease

Changes in apoptotic factors and caspase activation pathways during the postmortem aging of beef muscle.

Huang F1, Huang M2, Zhang H1, Zhang C1, Zhang D1, Zhou G3.
Food chemistry.Food Chem.2016 Jan 1;190:110-4. doi: 10.1016/j.foodchem.2015.05.056. Epub 2015 May 14.
The pathway of apoptosis (effector caspase activation) in beef muscle cells was investigated by examining the expression of apoptotic factors during postmortem (PM) storage of beef muscle. Results showed that caspase-3 could be activated in PM beef muscle. The expression of cytochrome c increased in
PMID 26212948

Autoimmune lymphoproliferative syndrome due to somatic FAS mutation (ALPS-sFAS) combined with a germline caspase-10 (CASP10) variation.

Martínez-Feito A1, Melero J2, Mora-Díaz S1, Rodríguez-Vigil C3, Elduayen R4, González-Granado LI5, Pérez-Méndez D1, Sánchez-Zapardiel E1, Ruiz-García R1, Menchén M1, Díaz-Madroñero J1, Paz-Artal E6, Del Orbe-Barreto R7, Riñón M8, Allende LM9.
Immunobiology.Immunobiology.2016 Jan;221(1):40-7. doi: 10.1016/j.imbio.2015.08.004. Epub 2015 Aug 17.
Autoimmune lymphoproliferative syndrome (ALPS) is a primary immunodeficiency caused by impaired Fas/FasL-mediated apoptosis of lymphocytes and is characterized by chronic nonmalignant or benign lymphoproliferation, autoimmune manifestations and expansion of double negative (DN) T-cells (TCRαβ+CD4-
PMID 26323380

Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs.

Hugle M1, Belz K1, Fulda S1,2,3.
Cell death and differentiation.Cell Death Differ.2015 Dec;22(12):1946-56. doi: 10.1038/cdd.2015.59. Epub 2015 May 29.
Polo-like kinase 1 (PLK1) is frequently overexpressed in cancer, which correlates with poor prognosis. Therefore, we investigated PLK1 as therapeutic target using rhabdomyosarcoma (RMS) as a model. Here, we identify a novel synthetic lethal interaction of PLK1 inhibitors and microtubule-destabilizin
PMID 26024389