dibasic calcium phosphate

• リン酸水素カルシウム

関

anhydrous dibasic calcium phosphate、calcium hydrogen phosphate、dicalcium phosphate anhydrous

WordNet

1. a salt of phosphoric acid (同)orthophosphate, inorganic_phosphate
2. carbonated drink with fruit syrup and a little phosphoric acid
3. a white metallic element that burns with a brilliant light; the fifth most abundant element in the earths crust; an important component of most plants and animals (同)Ca, atomic number 20

PrepTutorEJDIC

1. 〈U〉リン酸塩 / 《複数形で》リン酸肥料
2. 『カルシウム』(金属元素;化学記号は『Ca』)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2014/05/25 10:31:13」(JST)

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[Wiki en表示]

Dicalcium phosphate
IUPAC name Calcium hydrogen phosphate dihydrate
Other names Calcium monohydrogen phosphate Phosphoric acid, calcium salt (1:1)
Identifiers
CAS number	7757-93-9 Y,  7789-77-7 (dihydrate)
PubChem	104805
ChemSpider	10605753 Y
UNII	L11K75P92J Y
Jmol-3D images	Image 1
SMILES [Ca+2].[Ca+2].[O-]P([O-])([O-])=O
InChI InChI=1S/2Ca.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+2;/p-3 Y Key: NEFBYIFKOOEVPA-UHFFFAOYSA-K Y InChI=1/2Ca.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+2;/p-3 Key: NEFBYIFKOOEVPA-DFZHHIFOAL
Properties
Molecular formula	CaHPO4
Molar mass	136.06 g/mol
Appearance	white powder
Density	2.929 g/cm3
Solubility in water	0.02 g/100 mL
Hazards
EU Index	Not listed
NFPA 704	0 1 0
Flash point	Non-flammable
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Y (verify) (what is: Y/N?)
Infobox references

Dicalcium phosphate, also known as dibasic calcium phosphate or calcium monohydrogen phosphate, is a type of calcium phosphate that is dibasic. It is usually found as the dihydrate, with the chemical formula of CaHPO₄•2H₂O, but it can be thermally converted to the anhydrous form. It is practically insoluble in water, with a solubility of 0.02 g per 100 mL at 25 °C. It contains about 29.5 percent calcium in its anhydrous form. On contact with water, it converts to hydroxyapatite, which is insoluble solid, and phosphoric acid

Preparation

Dicalcium phosphate is produced by the reaction of calcium chloride and phosphoric acid:

CaCl₂ + H₃PO₄ + 2 NaOH → CaHPO₄ + 2 NaCl + 2 H₂O

Calcium carbonate is also used in place of the calcium chloride and sodium hydroxide.

Uses

Dicalcium phosphate is mainly used as a dietary supplement in prepared breakfast cereals, dog treats, enriched flour, and noodle products. It is also used as a tableting agent in some pharmaceutical preparations, including some products meant to eliminate body odor. It is used in poultry feed. It is also used in some toothpastes as a tartar control agent.

References

See also

• Monocalcium phosphate
• Tricalcium phosphate

UpToDate Contents

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• 1. カルシウムおよびリン酸バランスの調節 regulation of calcium and phosphate balance
• 2. 慢性腎疾患における高リン血症の治療 treatment of hyperphosphatemia in chronic kidney disease
• 3. 成人における再発性カルシウム結石の予防 prevention of recurrent calcium stones in adults
• 4. 副甲状腺ホルモンの分泌および作用 parathyroid hormone secretion and action
• 5. 成人におけるカルシウム結石の危険因子 risk factors for calcium stones in adults

English Journal

• Comparative evaluation of drug release from aged prolonged polyethylene oxide tablet matrices: effect of excipient and drug type.

• Shojaee S1, Kaialy W2, Cumming KI1, Nokhodchi A3.
• Pharmaceutical development and technology.Pharm Dev Technol.2016 Mar;21(2):189-95. doi: 10.3109/10837450.2014.982823. Epub 2014 Nov 20.
• Polyethylene oxide (PEO) undergoes structural adjustments caused by elevated temperatures, which results in loss of its stability within direct compression tablets. The aim of this study was to evaluate the influence of filler solubility on the drug delivery process of matrix tablets containing drug
• PMID 25410967

• Amorphous polyphosphate-hydroxyapatite: A morphogenetically active substrate for bone-related SaOS-2 cells in vitro.

• Müller WE1, Tolba E2, Schröder HC2, Muñoz-Espí R3, Diehl-Seifert B4, Wang X5.
• Acta biomaterialia.Acta Biomater.2016 Feb;31:358-67. doi: 10.1016/j.actbio.2015.11.060. Epub 2015 Nov 30.
• There is increasing evidence that inorganic calcium-polyphosphates (polyP) are involved in human bone hydroxyapatite (HA) formation. Here we investigated the morphology of the particles, containing calcium phosphate (CaP) with different concentrations of various Na-polyP concentrations, as well as t
• PMID 26654764

• Compaction behavior and deformation mechanism of directly compressible textured mannitol in a rotary tablet press simulator.

• Tarlier N1, Soulairol I1, Bataille B1, Baylac G1, Ravel P2, Nofrerias I1, Lefèvre P3, Sharkawi T1.
• International journal of pharmaceutics.Int J Pharm.2015 Nov 10;495(1):410-9. doi: 10.1016/j.ijpharm.2015.09.007. Epub 2015 Sep 9.
• Textured mannitol powder is widely used as a pharmaceutical excipient for tablet compaction. In order to choose the right tableting parameters, it is necessary to understand its mechanical behavior during deformation under industrial tableting conditions. The aim of this study was to evaluate the me
• PMID 26363108

Japanese Journal

• 各種直打用賦形剤の流動性指数とせん断試験による評価

• 竹内 淑子,勝野 英里,矢島 俊輔 [他]
• 粉体工学会誌 51(2), 77-87, 2014
• NAID 40019975004

• 各種直打用賦形剤の流動性指数とせん断試験による評価

• 竹内 淑子,勝野 英里,矢島 俊輔,冨田 知香,田原 耕平,竹内 洋文
• 粉体工学会誌 51(2), 77-87, 2014
• … Anhydrous dibasic calcium phosphate, dibasic calcium phosphate hydrate, granulated lactose were examined for excipient.Flow properties and shearing properties of excipient powders and formulated mixture powders were determined. …
• NAID 130004545881

• 粉末積層造形法を用いた人工骨成形法の提案―成形骨の表面と内部の化学的組成―

• 山澤 建二,橋爪 大輔,中尾 愛子,安齋 正博,楢原 弘之,鈴木 裕
• 生体医工学 47(4), 359-365, 2009
• … In the experiments, we used conventional inkjet-type equipment and orthopedic filling-paste powder (BIOPEX), mainly containing alpha-tribasic calcium phosphate as the forming material. … To solidify the powder, we used a sodium chondroitin sulfate + dibasic sodium succinate anhydride aqueous solution as the binder liquid. …
• NAID 130004494098

Related Links

• Dibasic Calcium Phosphate (Inactive Ingredient) - Drugs.com

Learn about Dibasic Calcium Phosphate and find medications that contain this inactive ingredient. ... Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and ...

• Calcium phosphate dibasic 98.0-105.0% | Sigma-Aldrich

Sigma-Aldrich offers Sigma-C7263, Calcium phosphate dibasic for your research needs. Find product specific information including CAS, MSDS, protocols and references. ... Technical Service: Our team of scientists has experience ...

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★リンクテーブル★

リンク元	「リン酸水素カルシウム」「dicalcium phosphate anhydrous」「calcium hydrogen phosphate」
拡張検索	「anhydrous dibasic calcium phosphate」
関連記事	「phosphate」「calcium」

「リン酸水素カルシウム」

　　[★]

英

dibasic calcium phosphate、calcium hydrogen phosphate

化

アスラーン、アムロジピン、アムロジピンOD、アリーゼS配合、アリチア配合、エバスチンOD、ガスペラジン、ガスポート、ガスメット、ガスリック、クエチアピン、サニアーゼ配合、スルカイン配合、セルニルトン、ソファルコン、デプロメール、トラベルミン配合、トリプタノール、パロキセチン、ファモチジン、フェニルアラニン除去ミルク配合、フスコデ配合、フルボキサミンマレイン酸塩、プロモーション、ミルナシプラン塩酸塩、リシノプリル、リン酸水素カルシウム水和物、ロイシン・イソロイシン・バリン除去ミルク配合、ロンゲス、ロンゲリール、第二リン灰

関

無水リン酸水素カルシウム

「dicalcium phosphate anhydrous」

　　[★]

• 無水リン酸水素カルシウム

関

anhydrous dibasic calcium phosphate、calcium hydrogen phosphate、dibasic calcium phosphate

「calcium hydrogen phosphate」

　　[★]

• リン酸水素カルシウム

関

anhydrous dibasic calcium phosphate、dibasic calcium phosphate、dicalcium phosphate anhydrous

「anhydrous dibasic calcium phosphate」

　　[★]

• 無水リン酸水素カルシウム

関

calcium hydrogen phosphate、dibasic calcium phosphate、dicalcium phosphate anhydrous

「phosphate」

　　[★]

• n.

• (化合物)リン酸塩、リン酸エステル、ホスフェート、フォスフェート、リン酸

関

inorganic phosphate、orthophosphate、orthophosphoric acid、phospho、phosphoester、phosphoric、phosphoric acid、phosphoric acid ester、phosphorus

　 　 　

「calcium」

　　[★]

• カルシウム Ca2+