coronary flow reserve

同

CFR

WordNet

1. obtain or arrange (for oneself) in advance; "We managed to reserve a table at Maxims"
2. something kept back or saved for future use or a special purpose (同)backlog, stockpile
3. (medicine) potential capacity to respond in order to maintain vital functions
4. the trait of being uncommunicative; not volunteering anything more than necessary (同)reticence, taciturnity
5. arrange for and reserve (something for someone else) in advance; "reserve me a seat on a flight"; "The agent booked tickets to the show for the whole family"; "please hold a table at Maxims" (同)hold, book
6. hold back or set aside, especially for future use or contingency; "they held back their applause in anticipation"
7. cause to flow; "The artist flowed the washes on the paper"
8. the amount of fluid that flows in a given time (同)flow_rate, rate of flow
9. any uninterrupted stream or discharge
10. cover or swamp with water
11. the act of flowing or streaming; continuous progression (同)stream
12. the motion characteristic of fluids (liquids or gases) (同)flowing
13. move or progress freely as if in a stream; "The crowd flowed out of the stadium" (同)flux
14. be abundantly present; "The champagne flowed at the wedding"
15. (botany) the trumpet-shaped or cup-shaped outgrowth of the corolla of a daffodil or narcissus flower
16. one or more circles of light seen around a luminous object
17. a long cigar with blunt ends
18. (anatomy) any structure that resembles a crown in shape
19. set aside for the use of a particular person or party
20. marked by self-restraint and reticence; "was habitually reserved in speech, withholding her opinion"-Victoria Sackville-West
21. surrounding like a crown (especially of the blood vessels surrounding the heart); "coronary arteries"

PrepTutorEJDIC

1. (特定の人・目的などのために)…‘を'『別にしておく』,『取っておく』;…‘を'『予約する』《+『名』+『for』+『名』(do『ing』)》 / (…のために)…‘を'『残しておく』,蓄えておく《+『名』+『for』+『名』》 / 〈権利など〉‘を'保留する / 〈C〉(特定の目的や将来使うために)取っておくもの,(…にための)蓄え《+『for』+『名』》 / 〈U〉(…のために)取っておかれた状態《+『for』+『名』》 / 〈C〉(特別の目的のため取ってある公の)特別保留地 / 〈U〉慎み,自制(self-control) / 〈C〉(政府・銀行などの)準備金,予備金,積立金 / 〈C〉《しばしば複数形で》予備軍 / 蓄えてある,予備の
2. 《副詞巳句始を伴って》〈気体・液体・電気などが〉『流れる』 / 《副詞[句]を伴って》〈言葉・人々などず〉流れるように続く / 〈心・場所などが〉(…で)いっぱいになる,満ちあふれる《+『with』+『名』》 / 《副詞[句]を伴って》〈髪・服などが〉長く垂れる;風になびく / 〈潮が〉満ちる / (…から)生じる,発生する《+『from』+『名』》 / 〈C〉《単数形で》(気体・液体・電気などの)『流れ』《+『of』+『名』》 / 〈C〉《単数形で》(言葉・人などの)絶え間のない(よどみのない)流れ《+『of』+『名』》 / 〈C〉《単数形で》(…の)洪水,はんらん《+『of』+『名』》 / 〈U〉《the flow》満ち潮,上げ潮
3. コロナ(皆既日食のときに見える光冠) / (太陽・月などの)かさ
4. 予約の,貸し切りの / (人,人の言動が)控え目な,遠慮がちな,打ちとけない
5. 冠状動脈の / 心臓の / 冠状動脈血栓(けっせん)症(coronary thrombosis)

Wikipedia preview

出典(authority):フリー百科事典『ウィキペディア（Wikipedia）』「2013/05/14 20:13:41」(JST)

wiki en

[Wiki en表示]

Coronary flow reserve (CFR) is the maximum increase in blood flow through the coronary arteries above the normal resting volume. Its measurement is often used in medicine to assist in the treatment of conditions affecting the coronary arteries and to determine the efficacy of treatments used.

Overview

When demand for oxygen in the myocardium is increased, the vascular resistance of the coronary arteries has the ability to reduce, and this can increase the volume of blood passing through the blood vessels. This reduction occurs because the arteries dilate, which causes an increase in the diameter of the lumen. The greatest potential for this change is normally in the branches (arterioles) of the coronary artery that penetrate the myocardium, rather than those on the surface of the heart.

Measurement

Coronary flow reserve can be measured through a variety of methods, including digital subtraction cineangiography with coronary catheterization, doppler echocardiography, and positron emission tomography (PET).

Medical implications

Coronary flow reserve is used in diagnostics and treatment of patients suffering from conditions such as coronary artery disease and syndrome X. In the treatment of these conditions, vasodilators are used to allow sufficient blood to flow past a stenosis, for example, and the measurement of CFR enables the efficacy of such interventions to be measured. In patients suffering from Anderson-Fabry disease, there is evidence to suggest that CFR can be reduced. When coronary flow reserve is used in medicine, it is often expressed with a numerical value, which is formed by dividing the maximal coronary blood flow by resting blood flow. This allows for an objective view, which can aid diagnosis and treatment.

See also

• Coronary circulation
• Vascular resistance
• Coronary artery

References

UpToDate Contents

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• 1. 冠動脈圧‐流量測定の臨床使用 clinical use of coronary artery pressure flow measurements
• 2. 疾患状態における冠微小循環 the coronary microcirculation in disease states
• 3. 定量的冠動脈造影：臨床応用 quantitative coronary angiography clinical applications
• 4. 心臓症候群X：正常冠動脈の狭心症 cardiac syndrome x angina pectoris with normal coronary arteries
• 5. 冠動脈ステント使用の一般原則 general principles of the use of intracoronary stents

English Journal

• The physiological significance of a coronary stenosis differentially affects contractility and mitochondrial function in viable chronically dysfunctional myocardium.

• Page BJ, Young RF, Suzuki G, Fallavollita JA, Canty JM Jr.SourceThe Center for Research in Cardiovascular Medicine, University at Buffalo, Buffalo, USA.
• Basic research in cardiology.Basic Res Cardiol.2013 Jul;108(4):354. doi: 10.1007/s00395-013-0354-0. Epub 2013 May 7.
• The reversibility of viable dysfunctional myocardium after revascularization is variable and the reasons for this are unknown. Using 2D-DIGE, we tested the hypothesis that this could reflect the extent of molecular remodeling of myocardial tissue in the absence of infarction. Swine with a progressiv
• PMID 23649354

• Vasodilatory Capacity of the Coronary Microcirculation is Preserved in Selected Patients With Non-ST-Segment-Elevation Myocardial Infarction.

• Layland J, Carrick D, McEntegart M, Ahmed N, Payne A, McClure J, Sood A, McGeoch R, Macisaac A, Whitbourn R, Wilson A, Oldroyd K, Berry C.SourceWest of Scotland Heart and Lung Centre, Golden Jubilee National Hospital, Glasgow, United Kingdom.
• Circulation. Cardiovascular interventions.Circ Cardiovasc Interv.2013 Jun 11. [Epub ahead of print]
• BACKGROUND: THE USE OF FRACTIONAL FLOW RESERVE IN PATIENTS WITH NONST-SEGMENTELEVATION MYOCARDIAL INFARCTION (NSTEMI) IS A CONTROVERSIAL ISSUE. WE UNDERTOOK A STUDY TO ASSESS THE VASODILATORY CAPACITY OF THE CORONARY MICROCIRCULATION IN PATIENTS WITH NSTEMI WHEN COMPARED WITH A MODEL OF PRESERVED MI
• PMID 23756697

• Fractional flow reserve as a surrogate for inducible myocardial ischaemia.

• van de Hoef TP, Meuwissen M, Escaned J, Davies JE, Siebes M, Spaan JA, Piek JJ.SourceAMC Heart Center, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands.
• Nature reviews. Cardiology.Nat Rev Cardiol.2013 Jun 11. doi: 10.1038/nrcardio.2013.86. [Epub ahead of print]
• Documentation of inducible myocardial ischaemia, related to the coronary stenosis of interest, is of increasing importance in lesion selection for percutaneous coronary intervention (PCI). Fractional flow reserve (FFR) is an easily understood, routine diagnostic modality that has become part of dail
• PMID 23752699

Japanese Journal

• Non-Invasive Diagnostic Workup of Patients With Suspected Stable Angina by Combined Computed Tomography Coronary Angiography and Magnetic Resonance Perfusion Imaging

• KIRSCHBAUM Sharon W.,NIEMAN Koen,SPRINGELING Tirza,WEUSTINK Annick C.,RAMCHARITAR Steve,VAN MIEGHEM Carlos,ROSSI Alexia,DUCKERS Eric,SERRUYS Patrick W.,BOERSMA Eric,DE FEYTER Pim J.,VAN GEUNS Robert-Jan M.
• Circulation journal : official journal of the Japanese Circulation Society 75(7), 1678-1684, 2011-06-25
• … Background: To evaluate additional adenosine magnetic resonance perfusion (MRP) imaging in the diagnostic workup of patients with suspected stable angina with computed tomography coronary angiography (CTCA) as first-line diagnostic modality. … In patients with a stenosis of >50% as visually assessed, MRP was performed and the quantitative myocardial perfusion reserve index (MPRI) was calculated. …
• NAID 10029126713

• Significance of the Anatomical Properties of a Myocardial Bridge in Coronary Heart Disease

• ISHIKAWA Yukio,KAWAWA Yoko,KOHDA Eiichi,SHIMADA Kazuyuki,ISHII Toshiharu
• Circulation journal : official journal of the Japanese Circulation Society 75(7), 1559-1566, 2011-06-25
• … A myocardial bridge (MB), partially covering the coronary artery, is a congenital anatomical variant usually present in the left anterior descending coronary artery (LAD). … MB causes coronary heart disease (CHD) by 2 distinct mechanisms influenced by the anatomical properties of the MB, such as its length, thickness, and location. …
• NAID 10029126127

• Impact of Obstructive Sleep Apnea on Myocardial Tissue Perfusion in Patients With ST-Segment Elevation Myocardial Infarction

• NAKASHIMA Hiroshi,MUTO Shigenori,AMENOMORI Kentarou,SHIRAISHI Yosinori,NUNOHIRO Tatsuya,SUZUKI Shin
• Circulation journal : official journal of the Japanese Circulation Society 75(4), 890-896, 2011-03-25
• … This study was designed to examine the hypothesis that OSA may impair the coronary microcirculation in patients with ST-segment elevation myocardial infarction (STEMI). … Methods and Results: The present study included 100 patients with a first STEMI who underwent primary percutaneous coronary intervention (PCI) within 12h from onset. … Coronary flow velocity at baseline and at maximum hyperemia was measured using a Doppler guidewire following PCI. …
• NAID 10028103303

Related Links

• Coronary flow reserve. - National Center for Biotechnology ...

Gould KL, Lipscomb K, Hamilton GW. Physiologic basis for assessing critical coronary stenosis. Instantaneous flow response and regional distribution during coronary hyperemia as measures of coronary flow reserve. Am J Cardiol. ...

• coronary flow velocity reserve (CFVR) - Allie: Related ...

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★リンクテーブル★

リンク元	「冠血流予備能」
関連記事	「reserve」「flow」「coronary」「corona」

「冠血流予備能」

　　[★]

英

coronary flow reserve

同

冠状血管予備能 coronary vascular flow reserve

関

冠血流

「reserve」

　　[★]

• 予備、準備、貯蔵、蓄え、余裕量、準備する、貯蔵する、確保する、保留する、予約する、貯蔵型の

関

arrange、arrangement、book、pool、pooling、preliminary、preparation、preparatory、prepare、preparedness、preservation、preserve、reservation、spare、storage、store、stored、suspend、withhold

　 　 　 　 　 　 　

「flow」

　　[★]

• n.

• 流れ、流動、流速、流量

• v.

• 流動する、流れる

関

current、flow rate、flow velocity、flux、mobilization、run、stream、streaming

　 　 　 　 　 　 　 　 　

「coronary」

　　[★]

• adj.

• 冠血管の、冠状動脈の

関

coronary artery、coronary vessel

　 　

「corona」

　　[★] コロナ帯