補体C3b
- 関
- C3b complement
WordNet
- make complete or perfect; supply what is wanting or form the complement to; "I need some pepper to complement the sweet touch in the soup"
- a complete number or quantity; "a full complement"
- one of a series of enzymes in the blood serum that are part of the immune response
- something added to complete or embellish or make perfect; "a fine wine is a perfect complement to the dinner"; "wild rice was served as an accompaniment to the main dish" (同)accompaniment
- number needed to make up a whole force; "a full complement of workers" (同)full complement
- a word or phrase used to complete a grammatical construction
- either of two parts that mutually complete each other
- the 3rd letter of the Roman alphabet (同)c
- (music) the keynote of the scale of C major
- a general-purpose programing language closely associated with the UNIX operating system
PrepTutorEJDIC
- (あるものを完全にするため)(…を)補う物(事)《+『of』+『名』》 / 補語(文法で文の成分の一つ) / (必要な)全数,全量;(船の)定員 / …を補足する,補う
- carbonの化学記号
UpToDate Contents
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- 1. 補体経路 complement pathways
- 2. 補体系の制御因子および受容体 regulators and receptors of the complement system
- 3. 補体系の後天性疾患 acquired disorders of the complement system
- 4. 補体系の概要および臨床的評価 overview and clinical assessment of the complement system
- 5. 補体介在性溶血性尿毒症症候群 complement mediated hemolytic uremic syndrome
English Journal
- Expression and functional analysis of properdin in zebrafish Danio rerio.
- Zhang Y, Chen J, Yao F, Ji D, Li H, Zhang S.SourceLaboratory for Evolution & Development, Institute of Evolution & Marine Biodiversity, Department of Marine Biology, Ocean University of China, Qingdao 266003, China.
- Developmental and comparative immunology.Dev Comp Immunol.2013 Jun;40(2):123-31. doi: 10.1016/j.dci.2013.02.001. Epub 2013 Feb 15.
- Properdin, an upregulator of the alternative complement pathway, has been thoroughly studied in the mammalian species, but its research in the lower vertebrates such as fish is rather limited. Additionally, information regarding the structure-activity relationship of properdin remains rather fragmen
- PMID 23416932
- Dominant suppression of inflammation by glycan-hydrolyzed IgG.
- Nandakumar KS, Collin M, Happonen KE, Croxford AM, Lundström SL, Zubarev RA, Rowley MJ, Blom AM, Holmdahl R.SourceMedical Inflammation Research and Chemistry I Division, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 171 77 Stockholm, Sweden.
- Proceedings of the National Academy of Sciences of the United States of America.Proc Natl Acad Sci U S A.2013 May 13. [Epub ahead of print]
- A unique anti-inflammatory property of IgG, independent of antigen specificity, is described. IgG with modification of the heavy-chain glycan on asparagine 297 by the streptococcal enzyme endo-β-N-acetylglucosaminidase (EndoS) induced a dominant suppression of immune complex (IC)-mediated inflammat
- PMID 23671108
- Zinc-induced self-association of complement C3b and Factor H: implications for inflammation and age-related macular degeneration.
- Nan R, Tetchner S, Rodriguez E, Pao PJ, Gor J, Lengyel I, Perkins SJ.SourceUniversity College London, United Kingdom.
- The Journal of biological chemistry.J Biol Chem.2013 May 9. [Epub ahead of print]
- The sub-retinal pigment epithelial deposits (sRPEds) that are a hallmark of age-related macular degeneration (AMD) contain both C3b and mM levels of zinc. C3 is the central protein of complement, while C3u is formed by the spontaneous hydrolysis of the thioester bridge in C3. During activation, C3 i
- PMID 23661701
Japanese Journal
- 犬のエンドトキシンによる血球反応に於ける血漿成分の関与(I.大学院重点特別・研究科特別経費,平成18年度麻布大学公的研究助成金事業研究成果報告)
- 土屋 亮
- 麻布大学雑誌 15/16, 219-223, 2007
- … 霊長類動物では赤血球表面に存在する補体C3bリセプターCR1が活性化補体の除去に重要な役割を果す事が知られており,この結果は,犬の血小板表面に補体リセプターがLPS刺激により活性化した補体を除去している可能性が高い事を裏付けた。 …
- NAID 110006977950
- Isolation of Carp Complement Factor B and Formation of the C3-Convertase
- Nakao Miki,Nakahara Makiko,Yano Tomoki
- 九州大学農学部紀要 49(1), 101-110, 2004-02
- … Complement factor B (Bf) is a keycomponent that forms a catalytic side of C3-convertase of the alternative activation pathway. … This C3-convertase of tje alternative pathway of carp completement was assembled from purified C3, Bf and generation of C3b, the initial biologically active fragment derived from C3, was confirmed, suggesting a well conserved mechanism of the formation of the alternative pathway C3-convertase. …
- NAID 110001802503
Related Links
- The Complement System Overview Sometimes the interaction of antibodies with antigen is useful by itself. For example, coating a virus or bacterium thus preventing it from binding to — and invading — a host cell (e.g., antipolio ...
- Complement buffers. Complement activation and C3 binding experiments were performed with GVBS ++ buffer (Veronal-buffered saline [VBS] with 0.1% gelatin, 0.15 mM CaCl 2, and 1.0 mM MgCl 2). Complement activation was ...
★リンクテーブル★
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- 英
- complement C3b、C3b complement
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補体C3b
- 関
- complement C3b
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補体C3b不活性化因子、補体C3bインアクチベータ
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- 関
- 補体
- 古典的経路：C3からC4b2aのもつC3 convatase活性により生成し、C4b2a3bはC5 convertase活性を持つ (2008前期免疫学プリント 68)
- 別経路：C3からC3bBbPのもつC3 convertase活性により生成し、n(C3bBb)はC5 convertase活性を持つ (2008前期免疫学プリント 68)
- 別経路では細菌の表面でC3bが安定的に存在→オプソニン作用を有する
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- 同
- 補体第三成分 third component of complement
- 関
- 補体、C3a, C3b
- 補体の一つ
- C3は血清中に最も多く存在する
- C3 convertaseによってC3aとC3bを生じる
- C3 convertase活性を持つのは２つ
- 1. C4bC2a (古典的経路)
- 2. C3bBbP (別経路)
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- 補って完全にする物、補完物。(免疫)補体
- (必要な)全数、善良