combination contraceptive formulations

WordNet

1. the act of combining things to form a new whole (同)combining, compounding
2. the act of arranging elements into specified groups without regard to order
3. a collection of things that have been combined; an assemblage of separate parts or qualities
4. a coordinated sequence of chess moves
5. a group of people (often temporary) having a common purpose; "they were a winning combination"
6. a sequence of numbers or letters that opens a combination lock; "he forgot the combination to the safe"
7. an alliance of people or corporations or countries for a special purpose (formerly to achieve some antisocial end but now for general political or economic purposes)
8. a substance prepared according to a formula; "the physician prescribed a commercial preparation of the medicine" (同)preparation
9. the style of expressing yourself; "he suggested a better formulation"; "his manner of expression showed how much he cared" (同)expression
10. capable of preventing conception or impregnation; "contraceptive devices and medications" (同)prophylactic, antifertility
11. an agent or device intended to prevent conception (同)preventive, preventative, contraceptive_device, prophylactic device, birth control device

PrepTutorEJDIC

1. 〈U〉(…の)『結合』,組み合わせ;〈C〉(…の)組み合わされたもの,結合体《+『of』+『名』》 / 〈U〉(…との)『連合』,団結,共同,提携;〈C〉連合体,共同体,組合《+『with』+『名』》 / 〈C〉=combination lock / 《複数形で》(また《話》coms)コンビネーション(上下続きの肌着)
2. 〈U〉公式化 / 〈C〉明確な表現
3. 避妊薬;避妊用具 / 避妊[用]の

UpToDate Contents

全文を閲覧するには購読必要です。 To read the full text you will need to subscribe.

• 1. エストロゲン・プロゲスチン避妊剤の使用に関する概要 overview of the use of estrogen progestin contraceptives
• 2. 避妊：思春期に固有の問題の概要 contraception overview of issues specific to adolescents
• 3. 避妊の概要 overview of contraception
• 4. Approach to contraception in women with systemic lupus erythematosus
• 5. 緊急避妊剤 emergency contraception

English Journal

• Hormonal contraceptives: pharmacology tailored to women's health.

• De Leo V1, Musacchio MC2, Cappelli V2, Piomboni P2, Morgante G2.
• Human reproduction update.Hum Reprod Update.2016 Sep;22(5):634-46. doi: 10.1093/humupd/dmw016. Epub 2016 Jun 15.
• BACKGROUND: In recent years, several new oral contraceptives have become available. In some ways, they represent an evolution in terms of individualization and compliance on the part of women. The new formulations make it increasingly possible to prescribe a specific hormonal contraceptive on an ind
• PMID 27307386

• Norelgestromin/ethinyl estradiol intravenous infusion formulation optimization, stability and compatibility testing: A case study to overcome polysorbate 80 interference in chromatographic analysis.

• Abdallah IA1, Hammell DC2, Hassan HE3, Stinchcomb AL4.
• Journal of pharmaceutical and biomedical analysis.J Pharm Biomed Anal.2016 Jun 5;125:145-53. doi: 10.1016/j.jpba.2016.03.024. Epub 2016 Mar 19.
• Norelgestromin/ethinyl estradiol is a progestin/estrogen combination hormonal contraceptive indicated for the prevention of pregnancy in women. The very poor solubility and wettability of these drugs, along with their high potency (adsorption issues), give rise to difficulties in designing intraveno
• PMID 27018506

• Postmenopausal hormone therapy and the risk of breast cancer in Norway.

• Román M1,2, Sakshaug S3, Graff-Iversen S4, Vangen S2, Weiderpass E1,5,6,7, Ursin G1,8, Hofvind S1,9.
• International journal of cancer.Int J Cancer.2016 Feb 1;138(3):584-93. doi: 10.1002/ijc.29810. Epub 2015 Sep 3.
• There is convincing evidence that combined estrogen-progestin therapy (EPT) increases the risk of breast cancer. However, the effect of different formulations, preparations and routes of administration is largely unknown. Estrogen only-therapy (ET) is, in general, not associated or weakly associated
• PMID 26289549

Related Links

• The Effects of Different Formulations of Oral Contraceptive ...

The compositions and proprietary names of the oral contraceptives are given in Table 1 Table 1 Oral-Contraceptive Formulations.. Combination drugs containing levonorgestrel were classified according to progestin content as high ...

• Combination Estrogen–Progestin Oral Contraceptives — NEJM

Ovarian Cancer The risk of ovarian cancer is reduced by at least half among women who use oral contraceptives, including those who use low-estrogen formulations. 2,3 The reduction in risk occurs after relatively short ...

---

★リンクテーブル★

リンク元	「避妊」
関連記事	「combination」「formulation」「contraceptive」

「避妊」

　　[★]

英

contraception、sterilization、contraceptive

同

受胎調節 conception control fertility regulation、産児制限 birth control

関

殺菌、避妊薬、不妊化、不妊法、無菌化、滅菌、滅菌法、避妊法、受胎調節、男性避妊法、家族計画

male contraception oral contraceptives combination contraceptive formulations

各種避妊法の利点と欠点

G9M.90

• 経口避妊薬

• 利点：良性乳房腫瘍、子宮体癌、卵巣癌の発生率減少、子宮内膜症の症状緩和、月経困難症、月経前症候群の改善
• 欠点：虚血性脳卒中・喫煙者における虚血性心疾患・子宮頚癌、静脈血栓塞栓症のリスク増加

35歳以上で1日15本以上の喫煙者には禁忌

• 子宮内避妊器具 IUD

• 欠点：月経過多、妊娠後の子宮外妊娠・感染性流産リスク上昇

各種避妊法の避妊効果

参考1

• 100人の女性が使用1年目で何人妊娠するか

• 経口避妊薬(ピル)　　0.1人
• 不妊手術(男性)　　　0.1人
• 不妊手術(女性)　　　0.2人
• IUD　　　　　　　　1.0人
• コンドーム　　　　　2-12人
• オギノ式　　　　　　2-20人
• 殺精子剤　　　　　　3-21人

出典不明

• 経口避妊薬(ピル)　　0.3-8%
• IUD　　　　　　　　3-8% (薬物添加IUD 0.1-0.8%)
• コンドーム　　　　　3-14%
• ペッサリー　　　　　6-16%
• オギノ式 周期的禁欲法 1-25%

参考

• 1. method

http://www.iwate.med.or.jp/kenkouzoushin/touka/hinin.html

「combination」

　　[★]

• n.

• 組み合わせ、併用、配合、合併、化合、コンビネーション

関

ally、combinatorial、combine、combined application、complicate、compound、concomitant、concurrent、conjunction、matching、merge、merger、mixture、pair

　 　 　 　 　 　 　 　

「formulation」

　　[★]

• n.

• 処方、製剤、剤形、製剤形態

関

dosage、dosage form、drug product、formulate、medication、preparation、prescribe、prescription、Px、recipe

　 　 　

「contraceptive」

　　[★]

• adj.

• 避妊薬、避妊の

関

contraception、contraceptive agent、contraceptive drug、sterilization