WordNet
- a violent disturbance; "the convulsions of the stock market" (同)turmoil, upheaval
- violent uncontrollable contractions of muscles
- a physical disturbance such as an earthquake or upheaval
- of or relating to abnormal neuromuscular activity characterized by rapidly alternating muscle contraction and relaxation; "clonic spasm"
PrepTutorEJDIC
- 《複数形で》けいれん,ひきつけ / 《複数形で》とめどもない大笑い / 震動,激動;動乱
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- 1. 成人におけるてんかんのマネージメントの概要 overview of the management of epilepsy in adults
- 2. 成人におけるてんかんの外科的治療 surgical treatment of epilepsy in adults
- 3. 新生児痙攣の臨床的特徴、評価、および診断 clinical features evaluation and diagnosis of neonatal seizures
- 4. 小児における痙攣およびてんかん：分類、病因、および臨床的特徴 seizures and epilepsy in children classification etiology and clinical features
- 5. 小児における痙攣およびてんかん：初期治療およびモニタリング seizures and epilepsy in children initial treatment and monitoring
English Journal
- Munc18-1 haploinsufficiency results in enhanced anxiety-like behavior as determined by heart rate responses in mice.
- Hager T1, Maroteaux G2, Pont Pd2, Julsing J2, van Vliet R2, Stiedl O3.Author information 1Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands; Sylics BV, PO Box 71033, 1008 BA Amsterdam, The Netherlands.2Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands.3Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands; Department of Molecular and Cellular Neurobiology, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University Amsterdam, The Netherlands. Electronic address: oliver.stiedl@cncr.vu.nl.AbstractHeterozygous (HZ) missense mutations in the gene encoding syntaxin binding protein 1 (Stxbp1 or Munc18-1), a presynaptic protein essential for neurotransmitter release, causes early infantile epileptic encephalopathy, abnormal brain structure and mental retardation in humans. Here we investigated whether the mouse model mimics symptoms of the human phenotype. The effects of the deletion of munc18-1 were studied in HZ and wild-type (WT) mice based on heart rate (HR) and its variability (HRV) as independent measures to expand previous behavioral results of enhanced anxiety and impaired emotional learning suggesting mild cognitive impairments. HR responses were assessed during novelty exposure, during the expression and extinction of conditioned tone-dependent fear and during the diurnal phase. Novelty exposure yielded no differences in activity patterns between the two genotypes, while maximum HR differed significantly (WT: 770bpm; HZ: 790bpm). Retention tests after both auditory delay and trace fear conditioning showed a delayed extinction of the conditioned HR response in HZ mice compared to WT mice. Since the HR versus HRV correlation and HR dynamics assessed by nonlinear methods revealed similar function in HZ and WT mice, the higher HR responses of munc18-1 HZ mice to different emotional challenges cannot be attributed to differences in autonomic nervous system function. Thus, in contrast to the adverse consequences of deletion of a single allele of munc18-1 in humans, C57BL/6J mice show enhanced anxiety responses based on HR adjustments that extend previous results on the behavioral level without support of cognitive impairment, epileptic seizures and autonomic dysregulation.
- Behavioural brain research.Behav Brain Res.2014 Mar 1;260:44-52. doi: 10.1016/j.bbr.2013.11.033. Epub 2013 Dec 1.
- Heterozygous (HZ) missense mutations in the gene encoding syntaxin binding protein 1 (Stxbp1 or Munc18-1), a presynaptic protein essential for neurotransmitter release, causes early infantile epileptic encephalopathy, abnormal brain structure and mental retardation in humans. Here we investigated wh
- PMID 24304718
- Spice/K2 drugs - more than innocent substitutes for marijuana.
- Zawilska JB, Wojcieszak J.Author information Department of Pharmacodynamics, Medical University of Lodz, Lodz, Poland.AbstractSmokeable herbal mixtures containing synthetic agonists of cannabinoid receptors, known under brand names such as Spice, K2 and Kronic, represent a relatively new type of designer psychoactive drugs that has recently emerged on the recreational drug market. Although the Spice packages are labelled 'not for human consumption' or 'for aromatherapy only' and declared to be purely herbal, these herbal mixtures produce cannabis-like effects after smoking. This review surveys the current state of knowledge regarding the pharmacological properties of synthetic cannabimimetics and the prevalence and pattern of their use. Special emphasis is given to the negative consequences of using these products, including, among others, hallucinations, psychoses with delusions, seizures, cardiovascular symptoms and acute kidney injury.
- The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP).Int J Neuropsychopharmacol.2014 Mar;17(3):509-25. doi: 10.1017/S1461145713001247. Epub 2013 Oct 29.
- Smokeable herbal mixtures containing synthetic agonists of cannabinoid receptors, known under brand names such as Spice, K2 and Kronic, represent a relatively new type of designer psychoactive drugs that has recently emerged on the recreational drug market. Although the Spice packages are labelled '
- PMID 24169044
Japanese Journal
- 修正型電気痙攣療法後に遅発性間代性痙攣に伴う呼吸不全を起こした1症例
- 麻酔 = The Japanese journal of anesthesiology : 日本麻酔科学会準機関誌 66(7), 758-760, 2017-07
- NAID 40021257697
- Safety and efficacy of intravenous administration for tranexamic acid-induced emesis in dogs with accidental ingestion of foreign substances
- Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ, 2017
- NAID 130006188792
- インフリキシマブが著効した可逆性脳梁膨大部病変を有する軽症脳炎・脳症を合併した川崎病の幼児例
- 日本臨床免疫学会会誌 40(3), 190-195, 2017
- NAID 130005865101
Related Links
- convulsion [kon-vul´shun] a type of seizure consisting of a series of involuntary contractions of the voluntary muscles. Such seizures are symptomatic of some neurologic disorder; they are not in themselves a disease entity.
- Clonic convulsion definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation. Look it up now! ... These attacks were accompanied by frequent epileptic fits and clonic convulsion of certain ...
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★リンクテーブル★
| リンク元 | 「間代痙攣」「間代けいれん」「間代性けいれん」「間代性痙攣」 |
| 関連記事 | 「convulsion」「clonic」 |
「間代痙攣」
- 同
- 間代性痙攣
「間代けいれん」
「間代性けいれん」
「間代性痙攣」
「convulsion」
- n.
- 関
- clonic seizure、convulse、convulsive、convulsive seizure、cramp、focal seizure、generalized seizure、Jacksonian seizure、jerk、motor seizure、seizure、sensory seizure、somatosensory seizure、spasm、spasticity、tonic seizure、tonic-clonic seizure
「clonic」
- adj.
- 間代性の(痙攣)、クローヌス性の